Remove Disease Remove Medical Schools Remove Molecular Biology
article thumbnail

Advancements in upstream CLD for enhanced biotherapeutics production

Drug Discovery World

As the significance of large molecules continues to broaden across diverse modalities, emphasis on bispecific and multispecific antibodies to treat various disorders such as rheumatologic diseases, cancer, diabetes, anaemia, and infectious diseases becomes paramount.

article thumbnail

Advancing CAR-T therapy: how CD5 modulation is shaping cancer treatment

Drug Target Review

MR : We started by focusing on T-cell lymphoma because it is an orphan disease with very limited effective therapies, but, importantly, we think that CD5 deletion enhances any type of CAR T cell treatment. How might the CD5 knockout approach impact the treatment of other types of cancers beyond T-cell lymphoma?

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

A surprising new role for a major immune regulator

Broad Institute

Now, a team of MIT, Massachusetts General Hospital (MGH), Broad Institute of MIT and Harvard, and Harvard Medical School (HMS) researchers has discovered how STING activates those two pathways. Food and Drug Administration has not approved any STING agonist thus far, although multiple clinical trials are currently underway.

article thumbnail

Mediating BRAF-mutant melanoma resistance

Drug Target Review

Her research focus is on epigenetic regulation of melanoma and other cancers as well as wound healing, ageing biology and the development of novel epigenetic therapies targeting cancers and skin diseases and she is the owner of 15 issued and pending patents relevant to her research. Dr Alani received her M.D.

article thumbnail

A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Ozonoff is also an associate professor of pediatrics at Harvard Medical School and a scientist at Boston Children’s Hospital.

Virus 132
article thumbnail

GSK announces Dr Harry (Hal) C. Dietz MD to join the Board as Non-Executive Director

The Pharma Data

The appointment also builds on other recent Non-Executive Director appointments, including Charles (Charlie) Bancroft, former Executive Vice President at Bristol Myers Squibb (BMS), and Dr Anne Beal, former instructor in paediatrics at Harvard Medical School and Massachusetts General Hospital, and Chief Patient Officer at Sanofi.

article thumbnail

The use-case for NGS

Drug Discovery World

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development.