LifeSciVC

AUGUST 5, 2024

In fact, drug discovery scientists today would be hard pressed to do their jobs without access to a wealth of well-annotated human genome sequences and their association with specific diseases for target selection through to translational medicine. One final parallel to 2001.

Molecular Biology 90

Molecular Biology Production Drug Development Small Molecule 90

Drug Target Review

NOVEMBER 23, 2023

If so, the concepts we develop in simpler animals should help us understand the more complex systems in the human brain and make good hypotheses about how brain diseases arise and can be treated. He is also a Professor of Biology at the University of Leuven, a member of EMBO and a Fellow of the Academy of Medical Sciences.

Therapies 98

Therapies Molecular Biology Laboratories Government 98

Drug Target Review

FEBRUARY 19, 2024

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?

Molecular Biology 110

Molecular Biology Science Protein Expression Production 110

BMG Labtech

MARCH 11, 2024

This is reflected in scientific discoveries across many research disciplines including immunology , molecular biology , medicine, and diagnostics. Specific areas where they have had a wide impact include virology , bacteriology, biotechnology , fungal biology, cancer and oncology (e.g.

Vaccine 98

Vaccine Molecular Biology Laboratories Virus 98

The Pharma Data

JANUARY 26, 2021

Concomitant research in biomaterials, biomechanics, electrophysiology, and molecular biology has expanded the horizon of the orthopedics market. Rise in surgical practices pertaining to musculoskeletal systems such as healing of fractures and disease is expanding the growth of the orthopedics market.

Marketing 52

Marketing Disease Molecular Biology Research 52

Broad Institute

JUNE 21, 2023

With further development, the findings could inform a potential treatment that lowers oxygen levels in certain tissues in humans to reverse advanced disease. The study appeared recently in Human Molecular Genetics. “If Mootha’s lab has been studying hypoxia as a potential treatment for rare neurological diseases since 2016.

Treatment 98

Treatment Disease Molecular Biology Medical Schools 98

Drug Target Review

APRIL 19, 2024

Sibylla’s scientific founders come from very different scientific fields that do not usually speak to each other, such as theoretical physics, molecular biology and pharmaceutical chemistry. Our ongoing research and development are poised to explore these avenues, aiming to address complex diseases with novel therapeutics.

Molecular Biology 111

Molecular Biology Research Pharmaceuticals Small Molecule 111

Broad Institute

DECEMBER 13, 2023

Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A., Spanish (minor) Genetic Pertubation Platform (GPP) Mohammed Mutaher Harvard University Human Developmental and Regenerative Biology (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Science Engineering 52

Broad Institute

OCTOBER 24, 2024

He is currently interested in developing complex, high-throughput in vitro models of the heart using human stem cell derived cardiomyocytes to gain a better understanding of the underlying mechanisms of cardiac disease and identify new therapeutic targets to treat heart failure. Prior to joining Bayer and the PCL, DePalma earned his Ph.D.

Molecular Biology 52

Molecular Biology Engineering Laboratories Disease 52

Broad Institute

JANUARY 30, 2024

Bhattacharyya wears many coats today, splitting his time between the Broad and the infectious disease ward at MGH, where a diagnostic method he developed at Broad is now being tested to see if it helps patients quickly receive the best antibiotics for their infections. A combined MD/PhD program offered both opportunities.

Hospitals 137

Hospitals Virus Medical Schools Science 137

Broad Institute

AUGUST 16, 2023

The mitochondrial genome, which encodes just 13 proteins, is smaller and comparatively less well studied than the genome in the cell’s nucleus, even though mutations in mitochondrial DNA can cause a number of rare diseases. They found that copy number declines consistently with age, which is in line with previous studies.

DNA 98

DNA Molecular Biology Disease Regulations 98

Broad Institute

APRIL 25, 2024

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132

Virus Hospitals Disease Government 132

sptlabtech

JUNE 9, 2023

The field of genomics has witnessed a revolutionary transformation, leading to a better understanding of health and disease, as well the emergence of personalized medicine to improve therapeutic outcomes. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Laboratories 98

Laboratories Molecular Biology DNA Engineering 98

Fierce BioTech

JUNE 6, 2023

Harwell molecular biology spherical nucleic acid rare diseases Adaptive Biotechnologies Resource Type Whitepaper harwell logo.png Tue, 06/06/2023 - 09:31 Content Channel Devices Clinical Data Biotech Content Channel Fierce Biotech Homepage Landing Page Url More Info Byline Sponsored by: Harwell

Science 52

Science Therapies Molecular Biology Government 52

Drug Target Review

NOVEMBER 8, 2023

Cell therapies hold immense promise for revolutionising the treatment of some of the most challenging diseases, but several technological and logistical hurdles stand in the way of unlocking their full potential. By harnessing the fundamental biology of T cells, Senza5 can be used to improve the efficacy of almost any CAR-T therapy.

Therapies 116

Therapies Engineering Treatment Molecular Biology 116

Drug Target Review

NOVEMBER 27, 2023

This approach is highly targeted, as STRIs selectively inhibit the translation of a specific network of disease-causing proteins without affecting the broader cellular machinery. By directly inhibiting the translation of disease-causing proteins, STRIs offer a novel strategy to overcome resistance mechanisms. He received his B.S.

Molecular Biology 86

Molecular Biology Therapies Pharmaceuticals Treatment 86

The Pharma Data

NOVEMBER 10, 2021

“Targeting Shp2 as a remedy appears to actually worsen the complaint, at least in the case of Myc- driven hepatocellular melanoma (HCC) or liver cancer,” said Feng.

Disease 52

Disease Molecular Biology RNA Drugs 52

The Pharma Data

JANUARY 18, 2021

The funds will be used to advance its nose-on-chip platform to detect the characteristic smell linked to Parkinson’s disease (PD). Yesse Technologies scientists recently validated the presence of a distinctive smell, arising from an oily skin secretion called sebum, in patients diagnosed with Parkinson’s disease.

Disease 40

Disease Molecular Biology Licensing Licensing 40

Drug Target Review

SEPTEMBER 22, 2023

Moreover, their intricate 3D structure and cellular diversity offer a more precise replication of specific structures and functions, making them promising candidates in disease modelling and drug testing. CRISPR engineering in organoids for gene repair and disease modelling. Human organoids in basic research and clinical applications.

Clinical Research 116

Clinical Research Research Drug Development Molecular Biology 116

The Pharma Data

JANUARY 25, 2021

“The establishment of an Advisory Board focusing on Alzheimer’s disease, and the recruitment of such an impressive group of scientific and clinical leaders in this field is an extremely important step forward for the Company,” stated Paul Brennan, NervGen’s President & CEO. Dr.

Disease 40

Disease Clinical Development Molecular Biology Treatment 40

Broad Institute

AUGUST 7, 2023

In the context of inflammatory diseases where STING is overactivated, we can now start asking which of those molecular mechanisms is most important and contributes the most to the phenotype that we’re seeing.” Paper Cited Liu B, Carlson R, et al. Human STING is a proton channel. Online August 3, 2023.

Regulations 91

Regulations Clinical Trials Engineering Science 91

Drug Target Review

AUGUST 29, 2023

The implication of this work is that we have an unprecedented opportunity to advance a single tRNA medicine to unify treatment across a wide range of diseases with the same underlying genetic mutation, enabling us to provide medicines to patients, especially those with rare or ultra-rare diseases, with no or limited treatment options.

Science 98

Science Disease Molecular Biology Therapies 98

sptlabtech

JUNE 9, 2023

The field of genomics has witnessed a revolutionary transformation, leading to a better understanding of health and disease, as well the emergence of personalized medicine to improve therapeutic outcomes. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Molecular Biology 52

Molecular Biology DNA Laboratories Disease 52

DrugBank

FEBRUARY 9, 2023

1 Present address: Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark. They selected the most promising drugs that targeted the deregulated signaling axes in obese-diabetic individuals and reversed their disease signatures. Dutta et al.

Clinical Pharmacology 52

Clinical Pharmacology Molecular Biology DNA Licensing 52

The Pharma Data

MARCH 16, 2022

Johnsson has been Director of the Chemical Biology Department at the Max Planck Institute for Medical Research in Heidelberg since 2017. The methods he has developed for the targeted labeling of proteins in living cells have revolutionized cell biology. Early Excellence in Science Awards 2020.

Cell Biology 52

Cell Biology Molecular Biology Science Research 52

The Pharma Data

APRIL 28, 2021

Researchers are also using sophisticated machine learning and artificial intelligence to illuminate predictive relationships from highly complex and multi-modal data, including clinical, molecular, and digital data. These analytical tools are giving teams a look at diseases at a digital pathology level.

Molecular Biology 40

Molecular Biology Doctors Disease Treatment 40

Drug Target Review

FEBRUARY 28, 2024

Dr Rochlin earned a PhD in Molecular Biology and Genetics from Weill Cornell Medical College, conducting research at Sloan Kettering Institute, and a BA in Biology from the University of Pennsylvania. Human γδ TCR repertoires in health and disease. and MBA students with real-world consulting experiences.

Therapies 105

Therapies Engineering Molecular Biology Science 105

Elrig

APRIL 29, 2024

Jasmine has a background in neuroscience and genetic manipulation, with early works focused on using a combined structural and molecular biology approach to assess disease-associated proteins implicated in Alzheimer’s disease. Bioinformatics is all about bringing together different areas of knowledge.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

The Pharma Data

SEPTEMBER 15, 2020

“ Amgen addresses important scientific questions to advance care and improve the lives of patients with serious diseases, including oncology, inflammation and cardiometabolic diseases, among others,” said Flavius Martin , vice president of Oncology, Inflammation and Site Head at Amgen South San Francisco.

Targeted Protein Degradation 52

Targeted Protein Degradation Molecular Biology Small Molecule Science 52

Drug Target Review

JUNE 11, 2024

When choosing my bachelor’s degree, the choice was between pursuing a career in biology or in computer science. Biology won that battle, and I pursued a bachelor’s and master’s degree in biochemistry and molecular biology.

Engineering 64

Engineering Science Molecular Biology Doctors 64

The Pharma Data

FEBRUARY 22, 2021

Born in 1970, the British and American research scientist has been Director of the Department of Microbiome Research at the Max Planck Institute for Developmental Biology in Tübingen since 2016. Before, she was associate professor at Cornell University in the Department of Molecular Biology and Genetics.

Molecular Biology 40

Molecular Biology Science Vaccine Laboratories 40

The Pharma Data

NOVEMBER 9, 2021

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma. What’s more, chitinase 3-like-1 augments SARS CoV-2 infection.”

Small Molecule 52

Small Molecule Virus Molecular Biology Disease 52

Broad Institute

NOVEMBER 17, 2023

He studies the genetics of numerous common diseases, particularly neuropsychiatric genetics especially schizophrenia, autism, and ADHD. His research focuses on the function of synapses and their disruption in animal models (especially non human primate models) of neurodevelopmental and psychiatric disease.

Engineering 52

Engineering Organic Chemistry Molecular Biology Disease 52

Drug Target Review

JULY 1, 2024

As a non-NSAID, it reduces adverse effects associated with these pain relief drugs, including kidney injury, GI gastritis/ulceration and blood pressure elevation, which can affect patients with cardiovascular disease and the elderly. We set out to improve health by developing a novel non-opioid that avoids potential abuse.

Treatment 59

Treatment Clinical Trials Therapies Molecular Biology 59

The Pharma Data

OCTOBER 18, 2020

(NASDAQ:CDXC) today highlighted a new study published in The European Molecular Biology Organization Journal looking at the effect of nicotinamide riboside (NR) on maintaining telomeres, the protective regions at the end of DNA strands.

DNA 52

DNA Molecular Biology Disease Trials 52

Drug Target Review

AUGUST 29, 2024

MR : We started by focusing on T-cell lymphoma because it is an orphan disease with very limited effective therapies, but, importantly, we think that CD5 deletion enhances any type of CAR T cell treatment. How might the CD5 knockout approach impact the treatment of other types of cancers beyond T-cell lymphoma?

Therapies 59

Therapies Treatment Engineering Molecular Biology 59

Broad Institute

OCTOBER 16, 2024

Chan School of Public Health, lauded Studier for how the technology has enabled strategies for infectious disease control. He has a humble, self-effacing demeanor, and yet he is great at pushing people to make bold bets and to try to make the impossible possible." In a video message, Melissa J.

Vaccine 64

Vaccine RNA Laboratories Molecular Biology 64