Remove Disease Remove Molecular Biology Remove Protein Expression
article thumbnail

The mechanism of Semen Persicae?Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments

Chemical Biology and Drug Design

Therefore, this study is intended to explore the mechanism and target of SP-FC in the treatment of HS through network pharmacology combined with in vitro cell and molecular biology experiments. Based on the targets searched and obtained, a Venn diagram was plotted to acquire common targets of SP-FC-HS.

article thumbnail

Women in Stem with Dr Beate Mueller-Tiemann

Drug Target Review

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. Biochemistry and molecular biology fascinated me in school. Can you tell us about your journey in the field of STEM and the challenges you encountered along the way?

article thumbnail

Enhancing gene therapy with Circio

Drug Target Review

Secondly, circRNAs can be engineered for more efficient protein expression by carefully selecting and optimising the IRES element, a sequence motif derived from viruses and used to initiate cap-independent translation from circRNA. What improvements in protein expression and durability have been demonstrated by the circVec 2.1

article thumbnail

BioSpace Global Roundup: Cevec Licenses AAV Program to Biogen

The Pharma Data

Sepofarsen has been granted orphan drug designation in the United States and the European Union and received fast-track designation and rare pediatric disease designation from the FDA as well as access to the PRIME scheme by the EMA. based Mogrify Limited expanded its research collaboration with MRC Laboratory of Molecular Biology.