Broad Institute

DECEMBER 13, 2023

Hung Group, Infectious Disease and Microbiome Program Michael Bogaev Princeton University Molecular Biology (major), B.A., Neuroscience (minor) Lander Lab Nina Gonzalez Bates University Biological Sciences (major), B.A., Neuroscience (minor) Lander Lab Nina Gonzalez Bates University Biological Sciences (major), B.A.,

Molecular Biology 52

Molecular Biology Cell Biology Science Engineering 52

Drug Target Review

APRIL 19, 2024

Sibylla’s scientific founders come from very different scientific fields that do not usually speak to each other, such as theoretical physics, molecular biology and pharmaceutical chemistry. Our ongoing research and development are poised to explore these avenues, aiming to address complex diseases with novel therapeutics.

Molecular Biology 111

Molecular Biology Research Pharmaceuticals Small Molecule 111

LifeSciVC

AUGUST 5, 2024

In fact, drug discovery scientists today would be hard pressed to do their jobs without access to a wealth of well-annotated human genome sequences and their association with specific diseases for target selection through to translational medicine. One final parallel to 2001.

Molecular Biology 85

Molecular Biology Production Drug Development Small Molecule 85

Drug Target Review

SEPTEMBER 22, 2023

Moreover, their intricate 3D structure and cellular diversity offer a more precise replication of specific structures and functions, making them promising candidates in disease modelling and drug testing. CRISPR engineering in organoids for gene repair and disease modelling. at Southern Medical University in Guangdong, China.

Clinical Research 116

Clinical Research Research Drug Development Molecular Biology 116

Broad Institute

JUNE 21, 2023

With further development, the findings could inform a potential treatment that lowers oxygen levels in certain tissues in humans to reverse advanced disease. The study appeared recently in Human Molecular Genetics. “If Mootha’s lab has been studying hypoxia as a potential treatment for rare neurological diseases since 2016.

Treatment 98

Treatment Disease Molecular Biology Medical Schools 98

Drug Target Review

OCTOBER 30, 2024

Imagine being able to create an in vitro replica of a diseased organ to study the molecular mechanism underlying the illness. Now take a step further: envision testing drugs in these organoids to identify the ones that can treat disease safely and effectively without needing to run expensive clinical trials first.

Treatment 105

Treatment Disease Clinical Trials Molecular Biology 105

Science Daily: Pharmacology News

OCTOBER 16, 2024

Using innovative spatial proteomics -- one of the most advanced molecular biology tools -- the team identified the inflammatory JAK/STAT pathway as the main driver of disease. This rare but often fatal reaction to common medications causes widespread detachment of the skin.

Molecular Biology 59

Molecular Biology Treatment Disease Research 59

Broad Institute

AUGUST 7, 2023

MIT biology PhD student Bingxu Liu and Rebecca Carlson PhD ’23, a recent graduate of the Medical Engineering and Medical Physics program through the Harvard-MIT Division of Health Sciences and Technology, are the lead authors of the paper, which appears in Science. Paper Cited Liu B, Carlson R, et al. Online August 3, 2023.

Regulations 91

Regulations Clinical Trials Engineering DNA 91

Broad Institute

AUGUST 16, 2023

The mitochondrial genome, which encodes just 13 proteins, is smaller and comparatively less well studied than the genome in the cell’s nucleus, even though mutations in mitochondrial DNA can cause a number of rare diseases. They found that copy number declines consistently with age, which is in line with previous studies.

DNA 98

DNA Molecular Biology Disease Regulations 98

Drug Target Review

NOVEMBER 8, 2023

Cell therapies hold immense promise for revolutionising the treatment of some of the most challenging diseases, but several technological and logistical hurdles stand in the way of unlocking their full potential. By harnessing the fundamental biology of T cells, Senza5 can be used to improve the efficacy of almost any CAR-T therapy.

Therapies 116

Therapies Engineering Treatment Molecular Biology 116

Broad Institute

APRIL 25, 2024

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132

Virus Hospitals Disease Government 132

Drug Target Review

AUGUST 29, 2023

It’s also where I got exposed to career options beyond academia and learned about Flagship Pioneering, a venture creation firm that conceives, resources, and builds life science bio platform companies in health care and sustainability. One of my mentors asked me if I was ready to fail 90 percent of the time.

Science 98

Science Disease Molecular Biology Therapies 98

The Pharma Data

JANUARY 21, 2021

NASDAQ: REGN) and Society for Science (the Society) today named 40 finalists in the Regeneron Science Talent Search 2021, the nation’s oldest and most prestigious science and math competition for high school seniors. ” Regeneron Science Talent Search 2021 Fast Facts. Regeneron Pharmaceuticals, Inc.

Science 40

Science Engineering Molecular Biology Bioinformatics 40

Drug Target Review

FEBRUARY 28, 2024

from 2003 to 2006, covering the biotechnology and life-science tools sectors. Mr. Ho was an inductee into the McMaster University Alumni Gallery in 2020 and currently serves as a member of their Dean’s Advisory Board for the Faculty of Science. Human γδ TCR repertoires in health and disease. Science 294(5542):605-609 (2001).

Therapies 105

Therapies Engineering Molecular Biology Science 105

The Pharma Data

JANUARY 6, 2021

. Supports the Development of New Approaches to Treat Multiple Neurological Diseases. CytoDel” or “the Company”), a privately-held corporation, today announces the publication of preclinical data on the Company’s lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. NEW YORK, Jan.

Science 52

Science Molecular Biology Treatment Production 52

The Pharma Data

JANUARY 18, 2021

The funds will be used to advance its nose-on-chip platform to detect the characteristic smell linked to Parkinson’s disease (PD). Yesse Technologies scientists recently validated the presence of a distinctive smell, arising from an oily skin secretion called sebum, in patients diagnosed with Parkinson’s disease.

Disease 40

Disease Molecular Biology Licensing Licensing 40

The Pharma Data

MARCH 16, 2022

Johnsson has been Director of the Chemical Biology Department at the Max Planck Institute for Medical Research in Heidelberg since 2017. Johnsson has been Director of the Chemical Biology Department at the Max Planck Institute for Medical Research in Heidelberg since 2017. Early Excellence in Science Awards 2020.

Cell Biology 52

Cell Biology Molecular Biology Science Laboratories 52

Drug Target Review

JUNE 11, 2024

When choosing my bachelor’s degree, the choice was between pursuing a career in biology or in computer science. Biology won that battle, and I pursued a bachelor’s and master’s degree in biochemistry and molecular biology. In math and life and physical sciences, women now make up nearly half of the workforce.

Engineering 64

Engineering Science Molecular Biology Doctors 64

The Pharma Data

JANUARY 25, 2021

“The establishment of an Advisory Board focusing on Alzheimer’s disease, and the recruitment of such an impressive group of scientific and clinical leaders in this field is an extremely important step forward for the Company,” stated Paul Brennan, NervGen’s President & CEO. Dr.

Disease 40

Disease Clinical Development Molecular Biology Treatment 40

DrugBank

FEBRUARY 9, 2023

1 Present address: Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark. They selected the most promising drugs that targeted the deregulated signaling axes in obese-diabetic individuals and reversed their disease signatures. Dutta et al.

Clinical Pharmacology 52

Clinical Pharmacology Molecular Biology DNA Licensing 52

The Pharma Data

SEPTEMBER 15, 2020

The companies will receive priority admission or renewal for one year of lab bench space with access to core facilities at the MBC BioLabs life sciences incubator, including access to Amgen ‘s scientific experts and business leaders to help advance their scientific programs.

Targeted Protein Degradation 52

Targeted Protein Degradation Molecular Biology Small Molecule Science 52

The Pharma Data

FEBRUARY 22, 2021

Born in 1970, the British and American research scientist has been Director of the Department of Microbiome Research at the Max Planck Institute for Developmental Biology in Tübingen since 2016. Before, she was associate professor at Cornell University in the Department of Molecular Biology and Genetics.

Molecular Biology 40

Molecular Biology Science Vaccine Laboratories 40

Elrig

APRIL 29, 2024

My role involved generating and characterizing complex proteins critical for biological assay development, hit discovery, and structural biology. During this time, I had the opportunity to step in as an interim Discovery Sciences project lead, sparking my interest in project leadership.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

PLOS: DNA Science

AUGUST 22, 2024

Unforgettably, my daughter Heather threw up on the volcano, an early sign of gallbladder disease and to this day, her claim to fame. Not Just a Volcanic Eruption – Sinister Science, Too Spoiler alert! And for some reason Patterson reverts to longish paragraphs, perpetuating the “science as unfamiliar” stereotype.

DNA 64

DNA Virus Organic Chemistry Science 64

Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 118

Therapies DNA Virus Clinical Trials 118

Vial

MARCH 1, 2024

’s services include supporting life sciences research, analytical solutions, and diagnostics or developing and manufacturing therapeutic interventions. It ensures regulatory compliance for over 15 long-term post-authorization safety studies across eight disease indications. Based in Massachusetts, Thermo Fisher Scientific Inc.

Clinical Trials 52

Clinical Trials Clinical Research Trials Laboratories 52

The Pharma Data

NOVEMBER 9, 2021

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma. What’s more, chitinase 3-like-1 augments SARS CoV-2 infection.”

Small Molecule 52

Small Molecule Virus Molecular Biology Disease 52

Drug Target Review

FEBRUARY 26, 2024

Her research focus is on epigenetic regulation of melanoma and other cancers as well as wound healing, ageing biology and the development of novel epigenetic therapies targeting cancers and skin diseases and she is the owner of 15 issued and pending patents relevant to her research.

Therapies 59

Therapies Molecular Biology Regulations Medical Schools 59

Drug Target Review

AUGUST 29, 2024

MR : We started by focusing on T-cell lymphoma because it is an orphan disease with very limited effective therapies, but, importantly, we think that CD5 deletion enhances any type of CAR T cell treatment. He is also the president of the College of Sciences Alumni Board at Thomas Jefferson University.

Therapies 59

Therapies Treatment Engineering Molecular Biology 59

Drug Target Review

JUNE 19, 2024

There are many opportunities to address conditions of the eye, such as retinitis pigmentosa, dry age-related macular degeneration or any of the hundreds of inherited retinal diseases. Mr Culley has more than 30 years of business and scientific experience in the life sciences industry. from May 2017 until December 2022.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Broad Institute

OCTOBER 16, 2024

It is so important to recognize groundbreaking science and the remarkable individuals who have made a difference so more people are aware of these achievements," said Edythe Broad. "If Chan School of Public Health, lauded Studier for how the technology has enabled strategies for infectious disease control.

Vaccine 64

Vaccine RNA Laboratories Molecular Biology 64

Alta Sciences

MARCH 1, 2024

Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies pmjackson Fri, 03/01/2024 - 22:20 Recent advances in gene therapy have allowed for diseases to be approached differently. Gene therapy was first discovered in the 1960s, but only gained commercial interest in the 1980s.

Therapies 52

Therapies Laboratories Molecular Biology RNA 52

Elrig

APRIL 6, 2023

Ron discussed three major challenges when developing an organoid model for drug discovery work, as well as taking Artificial Intelligence and neuronal networks full circle, using molecular biology to engineer logic switches in hiPSCs. Congratulations to all our award winners.

Research 40

Research Molecular Biology Science Drugs 40

Alta Sciences

AUGUST 21, 2024

I have also learned a lot about the nuances of micropipettes that I would have never learned at school.” — Sheridan Moore , Research Associate Intern, Laboratory Sciences “My favorite part about interning at Altasciences is the potential for creating a long, meaningful career that I would be passionate about.

International 40

International Laboratories Science Molecular Biology 40

BMG Labtech

MARCH 8, 2023

In biology , scientific research on cell metabolism focuses on different topics such as understanding the fundamental metabolic processes, metabolic changes and their role in diseases (including cancer cell and tumor metabolism), the development of therapies, the identification of unknown metabolic processes and metabolites, etc.

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

The Pharma Data

SEPTEMBER 17, 2020

Currently, this portfolio includes molecular, serology and digital solutions which help diagnose and manage COVID-19 during the initial stages of infection, during the recovery phase, as well as following the resolution of infection. The molecular biology of coronaviruses. Science 369:77-81; DOI: 10.1126/science.abc1932.

Vaccine 52

Vaccine Virus Clinical Trials Immune Response 52

The Pharma Data

NOVEMBER 19, 2020

The program is being led by Sosei Heptares and progressed in collaboration with multiple companies including Syngene International, Domainex, Fidelta, o2h Discovery, Piramal, WuXi AppTec and the MRC Laboratory of Molecular Biology. Zhang, et al, Science (2020) DOI: 10.1126/science.abb3405. References. Hilgenfeld, Febs J.

Small Molecule 40

Small Molecule Structure Based Drug Design (SBDD) Molecular Biology International 40