LifeSciVC

AUGUST 5, 2024

In fact, drug discovery scientists today would be hard pressed to do their jobs without access to a wealth of well-annotated human genome sequences and their association with specific diseases for target selection through to translational medicine. One final parallel to 2001.

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Molecular Biology Production Small Molecule Drug Development 90

Drug Discovery World

JANUARY 26, 2023

Atomic AI is oriented at the cutting edge of AI, RNA, and structural biology. “We The post $35 million to advance AI-driven RNA structure platform appeared first on Drug Discovery World (DDW).

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Drug Discovery World

FEBRUARY 27, 2023

RT : A key challenge that has emerged is targeting a known RNA transcript associated with an “undruggable disease” with no knowledge of where to start on the transcript, more specifically, which parts of the transcript are even targetable through various therapeutic modalities. By Is there anything currently in the pipeline?

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Drug Discovery World

APRIL 3, 2023

AT : The major interest we see is in the targeted delivery of therapeutic molecules. We are working with partners to develop delivery vehicles for small molecule payloads as next-generation precision chemotherapy and supporting partners with targeted delivery and cell penetration for gene therapies.

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Science Molecular Biology Therapies Disease 130

Drug Target Review

JUNE 19, 2024

There are many opportunities to address conditions of the eye, such as retinitis pigmentosa, dry age-related macular degeneration or any of the hundreds of inherited retinal diseases. Just like small molecules and antibodies, cell therapies are changing how we treat patients.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

The Pharma Data

NOVEMBER 9, 2021

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma. What’s more, chitinase 3-like-1 augments SARS CoV-2 infection.”

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Drug Discovery World

NOVEMBER 17, 2022

Lu Rahman selects some recent synthetic biology innovations and the potential they hold to benefit drug discovery. . The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape.

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Engineering Molecular Biology Synthetic Chemistry DNA 130

Dark Matter Blog

JULY 16, 2021

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. My last stop at Arrakis Therapeutics is with a company targeting RNA with small molecules.

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Drug Discovery World

OCTOBER 16, 2023

Professor Henrik Daub , Founder and CSO, NEOsphere Biotechnologies looks at the advancements taking place in proteomics and how targeted protein degradation represents a promising approach for developing new treatments for life-threatening diseases. 1 The power of TPD stems from small molecules commonly referred to as degraders.

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Targeted Protein Degradation Small Molecule Molecular Biology Treatment 147

Drug Discovery World

APRIL 30, 2024

Whilst research into mRNA has been ongoing for decade, interest has sparked in recent years and research has begun to expand into areas of vaccinology, infectious diseases and other indications. If the body fails to make the right protein, diseases such as cancer, type II diabetes, neurological conditions, and metabolic diseases can occur.

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Therapies RNA Vaccine Small Molecule 130

Drug Target Review

APRIL 19, 2024

Sibylla’s scientific founders come from very different scientific fields that do not usually speak to each other, such as theoretical physics, molecular biology and pharmaceutical chemistry. Our ongoing research and development are poised to explore these avenues, aiming to address complex diseases with novel therapeutics.

Molecular Biology 111

Molecular Biology Pharmaceuticals Small Molecule Research 111

Elrig

APRIL 29, 2024

Fascinated by the potential of AI in medical research, I transitioned to BenevolentAI in early 2023 as a Biology Project Leader. There, I supported AI-enabled DD efforts in their small molecule portfolio. Bioinformatics is all about bringing together different areas of knowledge.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Finding promising antibodies against specific molecular targets, however, is no easy feat.

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The Pharma Data

SEPTEMBER 15, 2020

“ Amgen addresses important scientific questions to advance care and improve the lives of patients with serious diseases, including oncology, inflammation and cardiometabolic diseases, among others,” said Flavius Martin , vice president of Oncology, Inflammation and Site Head at Amgen South San Francisco.

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Targeted Protein Degradation Molecular Biology Small Molecule Science 52

Drug Target Review

FEBRUARY 15, 2024

Rising demand for animal protein has led to more factory farming, increasing the likelihood that diseases can spread among these animals then into humans. 5 Furthermore, ever larger numbers of humans are living in cities or travelling across borders, increasing the risk of diseases being transmitted person-to-person over a long range.

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