New Drug Approvals
MARCH 26, 2025
Institute of Organic Chemistry and Biochemistry of the AS CR, v.v.i. Bavtavirine can be used for HIV disease research. Benzonitrile, 4-[[4-amino-8-[4-[(1 E )-2-cyanoethenyl]-2,6-dimethylphenyl]-2-quinazolinyl]amino]- Gilead Sciences, Inc.; Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Drug Target Review
SEPTEMBER 28, 2023
I started my journey in chemistry – first as an undergraduate and then in my PhD programme at the University of Houston, where I focused on organic chemistry and nucleic acids chemistry. They needed reference materials for the disease in order to develop and validate diagnostic tests.
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Drug Target Review
JULY 4, 2023
In practice, some patients may be left managing a syndrome associated with the therapy along with the disease. In the ADC trial, the objective response rate (ORR) – defined as the percentage of patients whose disease decreased or disappears – was 42 percent whilst the ORR in the small molecule trial was 12.5
The Open Targets Blog
SEPTEMBER 21, 2023
After completing my PhD in organic chemistry at the University of Cambridge, I went to Canada as a Leverhulme Trust postdoctoral fellow. It’s a multi-dimensional, cross-disciplinary problem, requiring an understanding of genetics, of disease biology, and of drug discovery factors. I’m a chemist by training.
Drug Hunter
AUGUST 21, 2023
Obtaining adequate drug exposure in the brain is key to treating CNS diseases effectively. Prodrugs Remain in “Proof-of-Concept” Stages Prodrug strategies for CNS deliver have also been applied with varying success , with the most famous example being L-Dopa for Parkinson’s disease. Figure 18.
The Pharma Data
OCTOBER 23, 2020
Elmaleh’s research has yielded compounds with potential in oncology, heart disease and neurodegenerative conditions, BOSTON, MA, October 23, 2020 /24-7PressRelease/ — Marquis Who’s Who, the world’s premier publisher of biographical profiles, is proud to honor David.
Broad Institute
NOVEMBER 17, 2023
He studies the genetics of numerous common diseases, particularly neuropsychiatric genetics especially schizophrenia, autism, and ADHD. His research focuses on the function of synapses and their disruption in animal models (especially non human primate models) of neurodevelopmental and psychiatric disease.
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