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Introduction to Pharmacogenetics

Broad Institute

Introduction to Pharmacogenetics By Rose Circeo May 30, 2024 Breadcrumb Home Introduction to Pharmacogenetics The Primer on Medical and Population Genetics is a series of weekly lectures on genetics topics related to human populations and disease.

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Open Targets Platform 24.03 has been released!

The Open Targets Blog

  We have implemented this analysis for eight sources of target-disease association evidence where there is enough information available to make an assessment. The assessment is tailored to each dataset; this is detailed in our target-disease evidence documentation. million evidence. is included as independent evidence.

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Open Targets Platform 23.12 has been released!

The Open Targets Blog

The new page can be accessed from the target-disease associations page when searching for targets associated with a disease, and clicking on the target prioritisation factors tab. Target prioritisation view for Crohn's Disease. Clicking on one of the cells will bring up the data informing the assessment.

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A personal touch: the role of bioprinting in drug discovery

Drug Discovery World

The company envisions that its bioprinting technologies will help replicate complex disease models with subjects’ own cell lines to be cultured and tested for individual treatment which it states are not currently possible with conventional bioprinting and organ-on-a-chip technologies. .

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Integrating pharmacogenetics data: a new lens for target prioritisation

The Open Targets Blog

In December 2023, we introduced the pharmacogenetics widget in the Open Targets Platform, which brings in data from PharmGKB on the influence of genetic variation on drug responses. Pharmacogenetics examines the link between genetics and drug response, helping in the prioritisation of drug targets that minimise the risk of adverse effects.

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The use-case for NGS

Drug Discovery World

We can use NGS to better understand so-called “pharmacogenetics” so that we can predict how an individual may respond to a given treatment. RA: Are there any disease areas NGS technologies are having a particular impact in? However, NGS will have impact in any genetic-based diseases. DG : For sure!

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Agena Bioscience Granted EUA for High-Throughput, Low-Cost SARS-CoV-2 Panel

The Pharma Data

The system is a highly sensitive, cost-effective, mass spectrometry-based platform for high-throughput genetic analysis and is used globally in diverse research fields such as cancer profiling for solid tumors and liquid biopsies, inherited genetic disease testing, pharmacogenetics, agricultural genomics, and clinical research.