Disease, Screening Hits and Small Molecule

Advancements in hit identification for membrane protein drug discovery

Drug Target Review

APRIL 7, 2025

The challenge of GPCR drug discovery G protein-coupled receptors (GPCRs) are one of the most desirable and challenging target classes in drug discovery, as their mutation can lead to a wide range of diseases such as cancer, cardiovascular disorders and neurological conditions.

Fragment Screening

Fragment Screening Drugs Small Molecule Biophysical Assays

Pathogen data in ChEMBL

The ChEMBL-og

SEPTEMBER 1, 2021

Infectious disease is a leading cause of death globally and bioactivity data against pathogens (fungi, bacteria, viruses, and parasites) is an important category in ChEMBL, especially in light of the ongoing pandemic. In the full database, the organism_classification table holds the underlying data and can be used in bespoke SQL queries.

Cell Based Assays

Cell Based Assays Screening Hits Small Molecule Virus

Drug Discovery Digest

Advancements in hit identification for membrane protein drug discovery

Pathogen data in ChEMBL

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