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A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers have identified a molecule that helps more mitochondria function properly.
The discovery could lead to more targeted treatments, with fewer side-effects, for issues from lengthy COVID infections to autoimmune diseases like multiple sclerosis. Current anti-inflammatory drugs used for this purpose suppress the body's whole immune system, making patients more vulnerable to infection.
Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves neuron health in animal models of Alzheimer's disease, according to a new study. Experimental drug NU-9 -- a small molecule compound approved by the U.S.
THURSDAY, May 16, 2024 -- For anyone newly diagnosed with blood cancers known as lymphomas, their first question might be: What treatments can help?Of Of course, there have been big advances in chemotherapy against the disease, but treatments now go.
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The findings demonstrate the potential of this technology to pave the way for future treatments for a wide range of conditions such as Alzheimer's disease, amyotrophic lateral sclerosis, brain cancer, and drug addiction.
Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- approach: using Xenon gas. A phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.
Engineers have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice. It significantly reduced IBD symptoms and promoted the healing of damaged colon tissue without causing toxic side effects.
a new Italian incubator dedicated to the discovery and development of small molecule-based treatments for neurodegenerative diseases, announced today that it has adopted Collaborative Drug Discovery’s CDD Vault as its platform of choice for managing drug discovery data.
Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.
THURSDAY, July 20, 2023 (American Heart Association News) -- New guidelines detailing how to care for people with heart disease come with some easy-to-grasp warnings for patients. The chronic coronary disease guidelines from the American Heart.
2, 2024 -- Mpox cases have soared by 160% in Africa this year, as a lack of both vaccines and treatments hamper efforts to slow the spread of the virus.In a report released by the Africa Centers for Disease Control and Prevention on. FRIDAY, Aug.
WEDNESDAY, June 14, 2023 -- Celiac disease is a chronic disease that can’t be cured, but treatment can help with symptoms. This guide will break down what you need to know about celiac disease, including its causes and symptoms, along with.
THURSDAY, April 11, 2024 -- The discovery of a gene variant that rids the brain of toxic plaques linked to Alzheimer's might lead to new treatments for the disease, researchers report.The variant arises naturally in people who don't seem to get.
THURSDAY, April 4, 2024 -- There's a glimmer of hope for people afflicted by a rare artery-hardening disease than can lead to amputation.An existing medication called etidronate appears to help slow the buildup of calcium in arteries that's a.
4, 2024 -- Huntington's disease is a devastating, fatal neurological illness with little means of treatment, but a new study in mice offers a glimmer of hope. MONDAY, Nov. Huntington's occurs when inherited genes cause key proteins to fold and.
FRIDAY, June 14, 2024 -- Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies. Only 5% of therapies tested.
Still, the complexities of the disease and of drug development have brought hard-felt losses. The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists.
Centers for Disease Control and Prevention estimates that there were nearly 68,000 new cases of acute hepatitis C in 2020 and over 107,000 newly reported cases of chronic hepatitis C? THURSDAY, July 6, 2023 -- Did you know the U.S. To help you.
Researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.
THURSDAY, July 13, 2023 -- A preclinical study offers a potential new therapy for treatment-resistant prostate cancer, offering new hope for men with the disease. The study used the chemotherapy drug cisplatin, administered orally, to disrupt the.
The medicine will join Intercept’s Ocaliva as a treatment option for primary biliary cholangitis. Another drug, from the now Gilead-owned CymaBay, could be cleared for the condition by August.
Sales of the transthyretin amyloidosis treatment widely beat Wall Street forecasts in the first quarter. The company aims to extend its patent exclusivity.
Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with. THURSDAY, Feb. 6, 2025 -- The U.S.
THURSDAY, March 21, 2024 -- People with heart disease can stay healthier if they address their emotional problems as well as their physical ailments, a new study says.Treating anxiety and depression reduced ER visits and hospitalizations among.
Obesity drugs like Wegovy are proving useful in many other diseases. Polycystic ovary syndrome, a chronic condition that can cause infertility, may be one.
Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.
Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurodegenerative conditions.
A gene encoding a protein linked to tau production -- tripartite motif protein 11 (TRIM11) -- was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research.
Wherein JNK3 is specifically expressed in brain and emerges as therapeutic target, especially for neurodegenerative diseases. However, developing JNK3 selective inhibitors as chemical probes to investigate its therapeutic potential in diseases remains challenging.
However, new research suggests that a less aggressive approach to treating the disease has helped an increasing. MONDAY, Feb. 5, 2024 -- Rectal cancer often involves surgeries that can lead to a debilitating loss of bowel function for patients.
The figure depicts the neuroprotective role of exendin-4 in Alzheimer's disease and Parkinson's disease. Exendin-4's diverse therapeutic targets suggest its potential therapeutic uses in neurodegenerative ailments like Alzheimer's disease and Parkinson's disease and have garnered an increasing amount of attention.
23, 2024 -- Two new strategies using deep brain stimulation can improve symptoms of Parkinson’s disease, Duke University researchers have found.Doctors can efficiently improve symptoms of Parkinson’s by simultaneously targeting to. TUESDAY, Jan.
Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.
According to the company, FDA officials have signaled openness to using a surrogate endpoint for assessing accelerated approval of a treatment for limb-girdle muscular dystrophy.
An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study.
has a long history of medicinal use, particularly for gastrointestinal diseases. Patients with inflammatory bowel disease (IBD) report using cannabis to manage their symptoms, despite little data to support the use of cannabis or cannabis products to treat the disease. Cannabis sativa L.
The startup believes T cell engagers, rather than cell therapies, will prove the “right horse to bet on” in the race to develop new inflammatory diseasetreatments, its CEO said.
With new medications on the market or in the works for Alzheimer's disease and other kinds of dementia, a new study suggests that getting the diagnosis needed to access these new treatments may depend on where you live.
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