ASPET

APRIL 2, 2024

Bromine domain protein 2 (BRD2), a member of the Bromodomain and extraterminal domain (BET) protein family, is a crucial epigenetic regulator with significant function in various diseases and cellular processes. Notably, the potential role of BRD2 as a diagnostic marker and therapeutic target is discussed in the context of various diseases.

Disease 100

Disease Regulations Virus Research 100

addgene Blog

JUNE 22, 2023

Some of these viruses are completely inert, but others can cause diseases. Viruses have become a regular part of basic biological research as well as clinical therapy. These biological tools are useful because they ’ re derived from viruses that can infect people, cells, and animals. Nervous about handling viruses? That ’ s okay!

Virus 68

Virus Therapies Disease Research 68

Chemical Biology and Drug Design

DECEMBER 13, 2023

These strategies act by taking advantage of the weakness points of this attractive bioweapon to disable or attack it (itself), accordingly stop the entire viral reproduction, and effectively end the severe microbial infections such as the coronavirus disease 2019 (COVID-19). SARS-CoV-2) to infect humans and spread infections.

RNA 100

RNA Disease Virus Drugs 100

Chemical Biology and Drug Design

NOVEMBER 10, 2024

Combined with network pharmacology and experimental verification, this study found that platycodin D and luteolin in Jiegeng ( Platycodonis Radix ) may regulate inflammation through the IL-17 signaling pathway to treat influenza virus pneumonia.

Virus 100

Virus Treatment Regulations Disease 100

SCIENMAG: Medicine & Health

DECEMBER 21, 2023

Researchers have identified a previously unrecognized class of antibodies—immune system proteins that protect against disease—that appear capable of neutralizing multiple forms of flu virus.

Virus 77

Virus Vaccine Disease Research 77

Chemical Biology and Drug Design

APRIL 18, 2023

The severity of chagas disease remains a major concern in endemic areas and an emerging public health hazard in nonendemic countries. Abstract Twenty different infectious disorders induced by bacteria, viruses, and parasites are categorized as neglected tropical diseases (NTDs) by WHO.

Treatment 100

Treatment Disease Virus Therapies 100

Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

Virus 144

Virus RNA Laboratories Medical Schools 144

Science Daily: Pharmacology News

AUGUST 22, 2024

One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika and other diseases every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal. Another, Anopheles gambiae, spreads the parasite that causes malaria.

Virus 133

Virus Disease 133

SCIENMAG: Medicine & Health

DECEMBER 14, 2023

An international team of scientists led by geneticists and disease biologists from the University of Oxford and LMU Munich have used ancient DNA to trace the evolution of Marek’s Disease Virus (MDV). The findings, published today […]

DNA 67

DNA Virus International Disease 67

BioPharma Drive: Drug Pricing

JUNE 6, 2023

The biotech has raised about $65 million to test two ways to deliver larger genes into the body, each of which could help gene therapy treat more diseases.

Virus 104

Virus Therapies Disease 104

Drugs.com

MAY 8, 2024

WEDNESDAY, May 8, 2024 -- The virus behind COVID has mutated again, this time producing variants nicknamed FLiRT, the U.S. Centers for Disease Control and Prevention (CDC) has reported.The variants are appearing in wastewater sampling, the CDC.

Virus 130

Virus Disease 130

Broad Institute

JANUARY 8, 2024

Williams January 8, 2024 Credit: Susanna Hamilton, Broad Communications Researchers have developed virus-like particles that can deliver gene-editing cargo to cells, including those in the mouse brain. Delivery dilemma Gene editing approaches promise to treat a range of diseases by precisely correcting genetic mutations that cause disease.

Engineering 144

Engineering Research Virus DNA 144

addgene Blog

AUGUST 18, 2023

Yet these simple, small particles have quite the outsized impact – and not just on the disease front. Viruses are simple – a genome packaged in a protein shell (Taylor, 2014). They’re so simple that we can’t even decide if they’re alive or not.

Virus 70

Virus Packaging Disease 70

Science Daily: Pharmacology News

DECEMBER 4, 2023

While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins.

Disease 90

Disease Research Virus Government 90

Drug Target Review

JULY 7, 2023

Approximately three percent of the global population — 240 million people — experience autoantibody diseases, which occur when one’s own body attacks critical organs and tissues. This can create an abnormal immune response that attacks the cells of our bodies and contributes to the development of autoantibody diseases.

Disease 98

Disease Immune Response Therapies Treatment 98

Broad Institute

JUNE 25, 2024

If you only study a small, homogeneous population, you will probably miss something," said co-corresponding author Daniel (Dong) Wang, an assistant professor of medicine at Brigham and Women's Hospital and of nutrition at Harvard Chan School, and an associate member of Broad's Infectious Disease and Microbiome Program (IDMP).

Virus 135

Virus Hospitals Disease Nurses 135

Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

Marketing 132

Marketing Virus Disease 132

PLOS: DNA Science

JANUARY 25, 2024

A recent report in PLOS ONE analyzes DNA from an adenovirus and a herpes virus discovered in preserved feces – coprolites – from 5,500 to 7,000 years ago at an archaeological site in Japan. The post Chewing Gum Reveals Stone Age Diet and Disease appeared first on DNA Science.

Disease 95

Disease DNA Science Virus 95

Drugs.com

DECEMBER 1, 2023

Centers for Disease Control and Prevention said that a surge in respiratory illnesses in China is not being fueled by a new. FRIDAY, Dec. 1, 2023 (Healthday News) -- In testimony provided Thursday to members of Congress, the head of the U.S.

Testimonials 98

Testimonials Virus Disease 98

SCIENMAG: Medicine & Health

JANUARY 5, 2024

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader. Credit: UofL photo. When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader.

Virus 84

Virus Disease Research 84

Broad Institute

APRIL 25, 2024

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132

Virus Hospitals Disease Government 132

SCIENMAG: Medicine & Health

AUGUST 10, 2023

Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia. CHAPEL HILL, N.C. Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Platelets, or […]

Virus 83

Virus Disease 83

PLOS: DNA Science

JULY 27, 2023

That information led, thanks to vaccine shelved from the first SARS circa 2003, to the rapid development and deployment of mRNA vaccines against the new infectious disease. The owners of the felines all reported feeding their pets raw meat, and samples of the meat revealed not only flu virus genetic material, but also infectious virus.

Disease 88

Disease DNA Virus RNA 88

Drugs.com

JUNE 29, 2023

THURSDAY, June 29, 2023 -- Americans ages 60 and up can get their vaccine for respiratory syncytial virus (RSV) this fall, the U.S. Centers for Disease Control and Prevention announced Thursday. On Thursday, Dr. Rochelle Walensky, the outgoing CDC.

Vaccine 116

Vaccine Virus Disease 116

Drugs.com

OCTOBER 2, 2023

2, 2023 -- New research shows the COVID-19 virus can directly infect coronary arteries, inflaming fatty plaque inside them, which can increase the risk of heart disease and stroke. MONDAY, Oct. This may explain why some people who get COVID-19 have.

Virus 112

Virus Disease Research 112

Broad Institute

MAY 16, 2024

The enormous challenge of getting therapies past this barrier — a highly selective membrane separating the blood from the brain — has stymied the development of safer and more effective gene therapies for brain diseases for decades.

Therapies 137

Therapies FDA Approval Engineering Disease 137

PLOS: DNA Science

MAY 16, 2024

These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and Infectious Diseases in Frontiers in Science. COVID clearly caught us off guard.

Virus 97

Virus DNA RNA Vaccine 97

Drugs.com

NOVEMBER 12, 2024

12, 2024 -- A cutting-edge genetic test can rapidly detect and identify almost any kind of disease-causing microorganism in the human body, whether it’s a virus, bacteria, fungus or parasite, researchers say.Doctors have been using t. TUESDAY, Nov.

Virus 98

Virus Disease Research 98

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- In a new study, people living with HIV who got standard meds to keep the virus at bay also had much lower rates of Alzheimer's disease -- suggesting the drugs might also lower risks for the brain illness.It's.

Virus 98

Virus Disease Drugs 98

The Pharma Data

MARCH 23, 2022

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase. Polymerase is a viral protein that directs how Ebola virus replicates its genome as it infects new hosts. Drugs that target polymerase could potentially treat Ebola virus infections and save lives.

Virus 52

Virus Small Molecule Protein Production Research 52

The Pharma Data

APRIL 8, 2022

Using a Human Lung Chip that replicates the structures and functions of the lung air sac, or “alveolus,” the research team discovered that applying mechanical forces that mimic breathing motions suppresses influenza virus replication by activating protective innate immune responses. During his Ph.D.

Virus 52

Virus Immune Response Disease Clinical Trials 52

Drugs.com

DECEMBER 26, 2023

Now, a case involving a rare but fatal brain disease caused by the measles virus may make some rethink. TUESDAY, Dec. 26, 2023 -- Measles is incredibly contagious, and outbreaks are more common now as people decide against vaccinating their kids.

Virus 106

Virus Vaccine Disease 106

SCIENMAG: Medicine & Health

JULY 27, 2023

OVX836 demonstrated positive safety and immunogenicity data across three dose levels A notable signal of protection of 84% was observed against symptomatic influenza infection Lyon, France – July 28, 2023 – Osivax, a biopharmaceutical company developing vaccines to provide broad-spectrum protection against highly mutating infectious viruses, today (..)

Vaccine 65

Vaccine Disease Virus 65

Drugs.com

AUGUST 15, 2023

15, 2023 -- Mosquitoes can be a big pest, leaving behind itchy bumps on skin and potentially spreading serious diseases, such as West Nile virus. Sam Telford III is a professor of infectious disease and global health at Cummings School. TUESDAY, Aug.

Virus 98

Virus Disease 98

ProRelix Research

SEPTEMBER 7, 2023

Autoimmune disorders comprise several diseases in which the immune system mistakenly attacks and destroys the body’s own healthy cells instead of destroying bacteria and viruses to keep the body healthy. […] The post Autoimmune disorders and current developments of novel treatments under clinical trials appeared first on ProRelix Research.

Clinical Trials 105

Clinical Trials Trials Treatment Virus 105

The Pharma Data

SEPTEMBER 30, 2021

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a replacement treatment that would keep metastatic cancers cornered from the lungs. It involves a bodily injection of a virus called the cowpea mosaic virus. The research was published Sept.

Virus 52

Virus Engineering Treatment Research 52

SCIENMAG: Medicine & Health

NOVEMBER 13, 2023

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide. Despite the availability of a safe and effective vaccine for over 40 years, HBV remains a leading cause of liver disease and death.

Virus 93

Virus Vaccine Disease 93