BioPharma Drive: Drug Pricing

JUNE 6, 2023

The biotech has raised about $65 million to test two ways to deliver larger genes into the body, each of which could help gene therapy treat more diseases.

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Drugs.com

MAY 8, 2024

WEDNESDAY, May 8, 2024 -- The virus behind COVID has mutated again, this time producing variants nicknamed FLiRT, the U.S. Centers for Disease Control and Prevention (CDC) has reported.The variants are appearing in wastewater sampling, the CDC.

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Science Daily: Pharmacology News

DECEMBER 4, 2023

While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins.

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Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).

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Drugs.com

DECEMBER 1, 2023

Centers for Disease Control and Prevention said that a surge in respiratory illnesses in China is not being fueled by a new. FRIDAY, Dec. 1, 2023 (Healthday News) -- In testimony provided Thursday to members of Congress, the head of the U.S.

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Drugs.com

JUNE 29, 2023

THURSDAY, June 29, 2023 -- Americans ages 60 and up can get their vaccine for respiratory syncytial virus (RSV) this fall, the U.S. Centers for Disease Control and Prevention announced Thursday. On Thursday, Dr. Rochelle Walensky, the outgoing CDC.

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Drugs.com

OCTOBER 2, 2023

2, 2023 -- New research shows the COVID-19 virus can directly infect coronary arteries, inflaming fatty plaque inside them, which can increase the risk of heart disease and stroke. MONDAY, Oct. This may explain why some people who get COVID-19 have.

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Drugs.com

NOVEMBER 12, 2024

12, 2024 -- A cutting-edge genetic test can rapidly detect and identify almost any kind of disease-causing microorganism in the human body, whether it’s a virus, bacteria, fungus or parasite, researchers say.Doctors have been using t. TUESDAY, Nov.

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Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- In a new study, people living with HIV who got standard meds to keep the virus at bay also had much lower rates of Alzheimer's disease -- suggesting the drugs might also lower risks for the brain illness.It's.

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Drugs.com

DECEMBER 26, 2023

Now, a case involving a rare but fatal brain disease caused by the measles virus may make some rethink. TUESDAY, Dec. 26, 2023 -- Measles is incredibly contagious, and outbreaks are more common now as people decide against vaccinating their kids.

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BioPharma Drive: Drug Pricing

MAY 7, 2024

The company is using what it claims is the largest database of viral protein structures to unearth medicines for a range of diseases, said CEO and Flagship origination partner Lovisa Afzelius.

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Broad Institute

JANUARY 14, 2025

By Allessandra DiCorato January 14, 2025 Credit: Maria Nemchuk, Broad Communications Eric Minikel and Sonia Vallabh run a lab with a singular focus: preventing and treating prion disease within their lifetime. Its a huge privilege to have the opportunity to point these powerful new tools at our disease.

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Drugs.com

AUGUST 15, 2023

15, 2023 -- Mosquitoes can be a big pest, leaving behind itchy bumps on skin and potentially spreading serious diseases, such as West Nile virus. Sam Telford III is a professor of infectious disease and global health at Cummings School. TUESDAY, Aug.

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Broad Institute

JUNE 27, 2024

Science (2024) Related content New gene delivery vehicle shows promise for human brain gene therapy My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED Prion diseases lead to rapid neurodegeneration and death and are caused by misshapen versions of the prion protein in the brain.

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Drugs.com

SEPTEMBER 7, 2023

7, 2023 -- While it doesn't prevent infection altogether, new research shows the mpox vaccine does reduces the severity of disease in those who fall ill from the virus. THURSDAY, Sept. An international team of scientists found that those people who.

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addgene Blog

JUNE 22, 2023

Some of these viruses are completely inert, but others can cause diseases. Viruses have become a regular part of basic biological research as well as clinical therapy. These biological tools are useful because they ’ re derived from viruses that can infect people, cells, and animals. Nervous about handling viruses? That ’ s okay!

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Drugs.com

AUGUST 4, 2023

Centers for Disease Control and Prevention on Thursday recommended that all infants under the age of 8 months be given a new antibody shot to help guard against severe respiratory syncytial virus (RSV). FRIDAY, Aug. 4, 2023 – The U.S. The antibody.

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Science Daily: Pharmacology News

AUGUST 9, 2023

The drug tecovirimat is currently in use for the treatment of mpox -- the disease caused by monkeypox virus -- that spread worldwide in 2022. Tecovirimat is an anti-poxviral drug, and its use is driving the emergence of drug-resistant variants of the monkeypox virus.

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Drugs.com

JANUARY 7, 2025

7, 2025 -- That cold sore on your lip might be painful and unsightly, but it could also be a harbinger of debilitating brain aging.The oral herpes virus appears to be linked with Alzheimers disease, suggesting that the common i. TUESDAY, Jan.

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ASPET

APRIL 2, 2024

Bromine domain protein 2 (BRD2), a member of the Bromodomain and extraterminal domain (BET) protein family, is a crucial epigenetic regulator with significant function in various diseases and cellular processes. Notably, the potential role of BRD2 as a diagnostic marker and therapeutic target is discussed in the context of various diseases.

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Chemical Biology and Drug Design

DECEMBER 13, 2023

These strategies act by taking advantage of the weakness points of this attractive bioweapon to disable or attack it (itself), accordingly stop the entire viral reproduction, and effectively end the severe microbial infections such as the coronavirus disease 2019 (COVID-19). SARS-CoV-2) to infect humans and spread infections.

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addgene Blog

AUGUST 18, 2023

Yet these simple, small particles have quite the outsized impact – and not just on the disease front. Viruses are simple – a genome packaged in a protein shell (Taylor, 2014). They’re so simple that we can’t even decide if they’re alive or not.

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SCIENMAG: Medicine & Health

DECEMBER 21, 2023

Researchers have identified a previously unrecognized class of antibodies—immune system proteins that protect against disease—that appear capable of neutralizing multiple forms of flu virus.

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Chemical Biology and Drug Design

APRIL 18, 2023

The severity of chagas disease remains a major concern in endemic areas and an emerging public health hazard in nonendemic countries. Abstract Twenty different infectious disorders induced by bacteria, viruses, and parasites are categorized as neglected tropical diseases (NTDs) by WHO.

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Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.

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Covalent Modifiers

JANUARY 14, 2024

Piedra, and Yongcheng Song ACS Infectious Diseases 2023 DOI: 10.1021/acsinfecdis.3c00565 Chloroacetamide inhibitor 13 and epoxide inhibitor 30 were found to inhibit cellular SARS-CoV-2 replication with an EC68 (half-log reduction of virus titer) of 3 and 5 μM.

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SCIENMAG: Medicine & Health

DECEMBER 14, 2023

An international team of scientists led by geneticists and disease biologists from the University of Oxford and LMU Munich have used ancient DNA to trace the evolution of Marek’s Disease Virus (MDV). The findings, published today […]

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Broad Institute

JANUARY 8, 2024

Williams January 8, 2024 Credit: Susanna Hamilton, Broad Communications Researchers have developed virus-like particles that can deliver gene-editing cargo to cells, including those in the mouse brain. Delivery dilemma Gene editing approaches promise to treat a range of diseases by precisely correcting genetic mutations that cause disease.

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Drug Target Review

JULY 7, 2023

Approximately three percent of the global population — 240 million people — experience autoantibody diseases, which occur when one’s own body attacks critical organs and tissues. This can create an abnormal immune response that attacks the cells of our bodies and contributes to the development of autoantibody diseases.

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PLOS: DNA Science

JANUARY 25, 2024

A recent report in PLOS ONE analyzes DNA from an adenovirus and a herpes virus discovered in preserved feces – coprolites – from 5,500 to 7,000 years ago at an archaeological site in Japan. The post Chewing Gum Reveals Stone Age Diet and Disease appeared first on DNA Science.

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Broad Institute

JUNE 25, 2024

If you only study a small, homogeneous population, you will probably miss something," said co-corresponding author Daniel (Dong) Wang, an assistant professor of medicine at Brigham and Women's Hospital and of nutrition at Harvard Chan School, and an associate member of Broad's Infectious Disease and Microbiome Program (IDMP).

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Drugs.com

JUNE 29, 2023

THURSDAY, June 29, 2023 -- Americans ages 60 and up can get their vaccine for respiratory syncytial virus (RSV) this fall, the U.S. Centers for Disease Control and Prevention announced Thursday. On Thursday, Dr. Rochelle Walensky, the outgoing CDC.

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SCIENMAG: Medicine & Health

JANUARY 5, 2024

When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader. Credit: UofL photo. When the body encounters bacteria, viruses or harmful substances, its innate immune cells, neutrophils, assemble at the site to combat the invader.

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Broad Institute

APRIL 25, 2024

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

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PLOS: DNA Science

JULY 27, 2023

That information led, thanks to vaccine shelved from the first SARS circa 2003, to the rapid development and deployment of mRNA vaccines against the new infectious disease. The owners of the felines all reported feeding their pets raw meat, and samples of the meat revealed not only flu virus genetic material, but also infectious virus.

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SCIENMAG: Medicine & Health

AUGUST 10, 2023

Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia. CHAPEL HILL, N.C. Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Platelets, or […]

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Drugs.com

SEPTEMBER 6, 2023

6, 2023 -- Doctors are seeing a spike in severe cases of respiratory syncytial virus (RSV) among young children in Florida and Georgia, U.S. The Centers for Disease Control and Prevention sent an. WEDNESDAY, Sept. health officials warned Tuesday.

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