Conversations in Drug Development Trends

NOVEMBER 12, 2024

For example, once considered incurable and terminal, patients with sickle cell disease may reach new summits in their lives with gene editing technologies such as CRISPR to repair affected DNA and, in some cases, functionally cure the condition. These advanced therapeutics harness the power of molecular biology to improve human health.

Therapies 72

Therapies Clinical Supply Clinical Trials Trials 72

LifeSciVC

AUGUST 5, 2024

We are constantly reminded how we are in the midst of an artificial intelligence revolution of the drug development process which promises to completely transform how we develop drugs with increases in productivity of an order of magnitude or more. One final parallel to 2001.

Molecular Biology 88

Molecular Biology Production Drug Development Small Molecule 88

DrugBank

MAY 15, 2024

But as molecular biology has advanced, so too has our approach to finding new drugs. Its structure makes it incredibly difficult for drugs to bind effectively, which has stymied drug development for decades. This method was more about serendipity than science.

Small Molecule 81

Small Molecule Molecular Biology Drugs Disease 81

Codon

FEBRUARY 13, 2024

Various algorithms, trained on data from enormous databases of phages and bacteria, have been developed to predict phage-host relationships in silico rather than find them experimentally with lab work. Left) A molecular structure of bacteriophage T4, which infects E. The tech for this process already exists.

Therapies 125

Therapies Virus DNA Clinical Trials 125

Drug Target Review

JUNE 19, 2024

The other powerful benefit is that our cell lines can become any of the cell types of the human body – these cells have within their DNA the capability to become any of the more than 200 human cell types which you might want to manufacture. This provides some regulatory advantages, and of course, significant cost advantages.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Elrig

APRIL 29, 2024

Srinivasan has led the development of multiple computational pipelines to process data from different next generation sequencing techniques with applications in oncology, genome editing systems including CRISPR-Cas mediated DNA editing, and ADAR-mediated RNA editing.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

Alta Sciences

AUGUST 21, 2024

Internships at Altasciences: Q&A With Our Summer Interns nbartlett Thu, 08/22/2024 - 04:44 Internships at Altasciences are more than just a stepping stone—they’re a gateway to real-world-experience and professional growth, giving the next generation opportunities to help shape progress in the drug development industry.

International 40

International Laboratories Science Molecular Biology 40