LifeSciVC

OCTOBER 13, 2022

Ingredients for success When you think about it, success in gene therapy is not really dependent on patents and traditional drug development methodologies and functions. Revenue opportunities like this have never existed in the history of the pharmaceutical world — until now.

Therapies 40

Therapies Disease Treatment Marketing 40

Advarra

AUGUST 10, 2023

Given the relatively small populations affected by any one rare disease or condition, a pharmaceutical company developing an orphan drug may reasonably expect the final approved drug to generate relatively small sales (when compared with the drug development costs) and consequently incur a financial loss.

Drug Development 52

Drug Development Disease Therapies Engineering 52

Codon

FEBRUARY 13, 2024

The weakened dose of phages helped bacteria develop resistance, and the trial became yet another study that provided evidence phages are safe, but little more. Middle and Right) Once a bacteriophage lands on a cell, it injects its DNA through a tube (purple) into the unwilling host. The tech for this process already exists.

Therapies 135

Therapies Virus DNA Clinical Trials 135

Drug Target Review

JANUARY 5, 2024

Scientists from the Centre for Genomic Regulation and the Wellcome Sanger Institute have found the allosteric control sites in the KRAS protein, the highly sought after targets for drug development. In drug development, allosteric sites are preferred because they provide better specificity, reducing the likelihood of side effects.

Regulations 98

Regulations Pharmaceutical Companies DNA Drug Development 98

DrugBank

FEBRUARY 26, 2025

In response, researchers and pharmaceutical companies are exploring novel approaches to antibiotic development. The Growing Threat of Antibiotic Resistance Antibiotic resistance occurs when bacteria evolve mechanisms to evade the effects of drugs designed to kill them.

Therapies 52

Therapies Pharmaceutical Companies Pharmacokinetics Treatment 52

The Pharma Data

MARCH 22, 2021

We intend to submit these data to regulatory authorities as soon as possible,” said John Tsai, Head of Global Drug Development and Chief Medical Officer for Novartis. “We Novartis is the only pharmaceutical company which is pursuing four different cancer treatment platforms.

Therapies 52

Therapies Treatment Trials Pharmaceutical Companies 52

Codon

SEPTEMBER 29, 2024

mRNA was the intermediate stage between DNA and protein, a dynamic entity that shifted depending on the second-to-second needs of the cell, able to point out if a cell was cancerous or stressed, what kind of cell it was, and so on. It wasn’t a silver bullet to the hard problem of drug development, but it wasn’t too far off either.

Engineering 144

Engineering Virus DNA Therapies 144

DrugBank

NOVEMBER 4, 2024

While the demand for novel antibiotics is undeniable, the industry still struggles with the harsh realities of antibiotic drug development. This costly, high-risk development pipeline has high attrition rates and uncertain market returns.  

Pharmaceutical Companies 98

Pharmaceutical Companies Pharmaceuticals Government DNA 98

Codon

APRIL 24, 2025

We’re close to selling out of our second book —written in both text and DNA—and we recently launched a merchandise store. While China’s AI competitiveness may have blindsided the tech world, the pharmaceutical industry has already had quite a few “ DeepSeek Moments ” of its own.

Clinical Trials 100

Clinical Trials Trials Pharmaceutical Companies Licensing 100

Codon

NOVEMBER 3, 2024

As an undergraduate biology student, I spent some time in a TB lab working on antibiotic resistance — a growing concern for drug developers. The drug didn’t cure the animals at such low doses, but their health did improve, hinting at the drug’s efficacy. However, hope prevails.

Vaccine 106

Vaccine Trials Therapies Treatment 106