Codon

JUNE 25, 2024

However, they plod along as they clone plasmids—the loops of DNA that biologists use to manipulate and study organisms—because propagating them relies, in part, on the pace at which cells grow and divide. Most medicines, including insulin and semaglutide (the weight loss drug), are made using DNA cloning. However, E.

DNA 75

DNA RNA Laboratories Research 75

DrugBank

FEBRUARY 9, 2023

1 Present address: Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark. 3 Research Focus: Network-based drug repositioning strategy to identify drugs targeting obesity and type 2 diabetes. Dutta et al.

Clinical Pharmacology 52

Clinical Pharmacology Molecular Biology DNA Licensing 52

The Pharma Data

NOVEMBER 22, 2021

It’ll support AstraZeneca’s focus on specialised and perfection drugs and foster the discovery and development of coming generation rectifiers, including nucleotide- grounded, gene-editing and cell curatives. Over the once century, roughly 50 Nobel Prize winners in chemistry and physiology or drug have been associated with Cambridge.

Molecular Biology 52

Molecular Biology Laboratories Engineering Hospitals 52

DrugBaron

NOVEMBER 22, 2022

As a commercial drug discovery company, much of their progress has been shielded from public gaze, even as they made ground-breaking advances to the technology platform. Over the next seven years, we will see just how much impact these advances can make for drug discovery and development.

Bioinformatics 100

Bioinformatics Regulations Molecular Biology Engineering 100

Drug Target Review

JUNE 19, 2024

The other powerful benefit is that our cell lines can become any of the cell types of the human body – these cells have within their DNA the capability to become any of the more than 200 human cell types which you might want to manufacture. This provides some regulatory advantages, and of course, significant cost advantages.

Therapies 84

Therapies Small Molecule Pharmaceutical Companies Molecular Biology 84

Dark Matter Blog

JULY 16, 2021

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. Last stops at RNA My last roles in biotech were where my original passion began: DNA and RNA.

Small Molecule 52

Small Molecule RNA Clinical Trials DNA 52

Drug Target Review

JUNE 11, 2024

When choosing my bachelor’s degree, the choice was between pursuing a career in biology or in computer science. Biology won that battle, and I pursued a bachelor’s and master’s degree in biochemistry and molecular biology.

Engineering 64

Engineering Science Molecular Biology Doctors 64

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here. From Moazami et al.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here. From Moazami et al.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

MARCH 12, 2023

Notes on Progress is a monthly roundup of papers and ideas about biology and the future. “The recombinant DNA breakthrough has provided us with a new and powerful approach to the questions that have intrigued and plagued man for centuries. Biology is a Burrito. A new base editor to edit mitochondrial DNA.

DNA 52

DNA Engineering Therapies RNA 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

DECEMBER 17, 2023

Molecular biology, as the field came to be called 3 , pushed biology from an object of study, driven forward by gentleman scientists and precocious country clergymen, into a tool with which to solve urgent problems. Recombinant DNA technologies were invented in the 1970s.

Engineering 52

Engineering Molecular Biology Doctors DNA 52

BMG Labtech

MARCH 8, 2023

DNA, proteins, polysaccharides, etc.). They are strongly oxidizing and, at high concentrations, are deleterious to cells damaging DNA, proteins and lipids, and eventually leading to cell death. In anti-tumor therapy development, this effect is a main focus of drug discovery. These readouts also play a role in drug discovery.

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

Alta Sciences

AUGUST 21, 2024

Internships at Altasciences: Q&A With Our Summer Interns nbartlett Thu, 08/22/2024 - 04:44 Internships at Altasciences are more than just a stepping stone—they’re a gateway to real-world-experience and professional growth, giving the next generation opportunities to help shape progress in the drug development industry.

International 40

International Laboratories Science Molecular Biology 40

Drug Target Review

FEBRUARY 20, 2025

Throughout her career, she has focused on advancing therapeutic drug discovery and developing genetic therapies, making significant contributions to the field. Sabin earned her PhD in cellular and molecular biology from the University of Pennsylvania.

Virus 52

Virus Therapies Molecular Biology Treatment 52

Drug Target Review

DECEMBER 12, 2024

As a result, patients receiving ESC-derived therapies must also take immunosuppressive drugs potentially for life. Enter epigenetics Broadly speaking, epigenetics refers to the system of proteins and marks that sits atop our genome a system that modifies gene expression, guides cell differentiation, and functionally organises our DNA.

Therapies 59

Therapies DNA Molecular Biology Immune Response 59

Broad Institute

JANUARY 7, 2025

These stories and diagnoses, made possible by clinical genomics labs around the world analyzing DNA from patients and sharing their findings with each other to improve medical care, werent always so common. In 2002, when Rehm was building such a lab at Mass General Brigham, she quickly realized how siloed these labs were.

Disease 121

Disease Science Laboratories Medical Schools 121

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Link Mathematical modeling and synthetic biology , by Chandran D. Drug Discovery Today: Disease Models (2008). Link Graphic Notations →Synthetic Biology Open Language Visual: An Open-Source Graphical Notation for Synthetic Biology , by Quinn J. . & Xie X.S.

DNA 95

DNA Cell Biology Molecular Biology Engineering 95

Codon

AUGUST 10, 2023

Journal of Molecular Biology (1961). Link Mathematical modeling and synthetic biology , by Chandran D. Drug Discovery Today: Disease Models (2008). Link Graphic Notations →Synthetic Biology Open Language Visual: An Open-Source Graphical Notation for Synthetic Biology , by Quinn J. . & Xie X.S.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

NOVEMBER 1, 2024

I’ve chosen these two because I think they are the linchpin by which we’ll be able to build broadly useful AI models for cell and molecular biology. Synthesizing a single human protein-coding gene costs several hundred dollars and even a simple PCR machine (used for amplifying DNA) costs between $1,500 and $50,000.

DNA 114

DNA RNA Molecular Biology Laboratories 114