LifeSciVC

APRIL 26, 2024

Beyond simply backing great science (separating the wheat from the chafe), setting a company up properly is critical, and early choices can get locked into the DNA of the company. Some continue to do so today, unfortunately, but there appears to be less of it happening.

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DNA Science Marketing Clinical Trials 117

The Pharma Data

DECEMBER 23, 2020

” Dr. Stanley Plotkin , Professor Emeritus at The Wistar Institute, said, “INOVIO’s DNA vaccine appeared to be quite safe with few significant reactions but yet induced both antibody and T cell responses to SARS-CoV-2.” About INOVIO’s DNA Medicines Platform. mg and 2.0

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DNA Vaccine Clinical Trials Immune Response 40

The Pharma Data

SEPTEMBER 1, 2020

The mass surveillance fears come from activists who believe that the DNA samples from the test will be harvested along with a citizen’s personal data to help China expand their surveillance programme from the mainland to the largely self-governing region. million. .

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DNA Virus Government Hospitals 52

The Pharma Data

DECEMBER 20, 2020

SN14 works by targeting the coronavirus’ nucleocapsid and spike proteins to prevent viral replication using the company’s ImmunoBody DNA vaccine technology. The company, along with partners University of Nottingham and Trent University, received a British government grant to support the study. .

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Clinical Trials Vaccine Pharma Companies Trials 52

Drug Target Review

APRIL 17, 2024

His lab applies approaches from computational biology and machine learning to unravel the molecular determinants of response to immune checkpoint blockade therapy, understand the co-evolution of tumour cells and the human immune system during cancer evolution, and learn the complex rules that govern T cell epitope recognition and immune escape.He

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Immune Response Laboratories DNA Virus 106

The Pharma Data

SEPTEMBER 3, 2020

One example of current technology is CRISPR, a biological system for altering DNA discovered in 2012. CRISPR scans the genome looking for the right location, and then uses “molecular scissors” to snip through the faulty DNA. While effective in the lab, the process is less than perfect and can cut out too much DNA.

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DNA International Science Disease 52

Codon

APRIL 17, 2025

Plastic leaves do not emit organic signals and contain no DNA, so any mimicry could imply some kind of primitive vision. Such vascular differences are governed by auxin, a plant hormone that regulates leaf venation and shape.

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Research DNA Engineering Government 58

PLOS: DNA Science

JUNE 8, 2023

That was so in 1977, when “intervening DNA sequences” – aka “introns” – were discovered to interrupt protein-encoding genes. Because the edits are in RNA, and not DNA, they are fleeting. The post How (and Why) the Octopus Edits its RNA appeared first on DNA Science.

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RNA DNA Science Laboratories 52

The Open Targets Blog

APRIL 25, 2023

Right: Wellcome Genome Campus, photo by Olesya Razuvayevskaya A sense of place Bletchley Park consists of a mansion built in the 19th century set in a large estate and was purchased in 1938 by the Head of the Secret Intelligence Service, Admiral Sir Hugh Sinclair, to house the UK Government Code and Cypher School 3.

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DNA Government Engineering Laboratories 52

FDA Law Blog: Biosimilars

APRIL 4, 2023

The South Korean government has recently announced its plan to provide support for the growth of the nation’s biohealth industry, aiming to establish it as a significant and strategic sector in the nation, similar to the semiconductor industry.

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Production DNA Pharmaceuticals Government 52

DrugBank

JANUARY 29, 2025

Gene Therapy Gene therapy operates on the principle of modulating the DNA blueprint of cells to induce a therapeutic response. The AAV genome, comprising single-stranded DNA, can persist in the host cell nucleus as an episome or integrate into the host genome at a specific site on chromosome 19.

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Therapies DNA RNA Disease 52

Drug Target Review

APRIL 3, 2024

Everything started in school with an experiment on isolating DNA from bananas. Making a little tangle of DNA visible to the eye and understanding that this is the basis of complex organisms, which might be altered in disease, was the defining moment for my future path in life sciences.

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Science Clinical Development Treatment DNA 106

The Pharma Data

OCTOBER 18, 2020

(NASDAQ:CDXC) today highlighted a new study published in The European Molecular Biology Organization Journal looking at the effect of nicotinamide riboside (NR) on maintaining telomeres, the protective regions at the end of DNA strands. Telomeres are “caps” at the end of chromosomes that protect DNA from getting worn away as cells replicate.

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DNA Molecular Biology Disease Trials 52

Perficient: Drug Development

AUGUST 31, 2024

In fact, some of these improvements might be easier to fund than a straight governance play. In fact, Unity Catalog provides performance benefits in addition to governance advantages. This is why monitoring needs to be built onto your development DNA. Take advantage of Databricks pools’ ability to prewarm clusters.

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Government DNA Engineering 52

The Pharma Data

JANUARY 7, 2021

OraSure, together with its wholly-owned subsidiaries, DNA Genotek, Diversigen, and Novosanis, provides its customers with end-to-end solutions that encompass tools, services and diagnostics. OraSure Technologies empowers the global community to improve health and wellness by providing access to accurate, essential information.

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DNA Laboratories Government Hospitals 40

Codon

OCTOBER 13, 2024

The chefs at Farma know that by embracing food technologies such as recombinant DNA, precision fermentation, and cell culture, food can become more nutritious and better for the planet. is just over $3 billion dollars — profitable enough that the federal and Florida state government spent over $1.3 The citrus industry in the U.S.

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Engineering Virus Production DNA 104

The Pharma Data

MARCH 30, 2021

Targeted radioligand therapy is a type of precision medicine combining two key elements: a targeting compound, or ligand, and a radioactive isotope, causing DNA damage that inhibits tumor growth and replication. We believe this technology has the potential to transform many patients’ lives.”.

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Drug Target Review

JANUARY 9, 2024

This discovery begins to solve a wider question posed by the lab: what governs how cells assemble and work together in the body, and can the cells be taken out of their natural context and recombined into different ‘body plans’ to do other functions by design?

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Laboratories Immune Response DNA Science 59

The Pharma Data

JANUARY 24, 2021

OraSure, together with its wholly-owned subsidiaries, DNA Genotek, Diversigen, and Novosanis, provides its customers with end-to-end solutions that encompass tools, services and diagnostics. OraSure Technologies empowers the global community to improve health and wellness by providing access to accurate, essential information.

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Research Bioinformatics Laboratories International 40

The Pharma Data

NOVEMBER 23, 2020

24, 2020 /PRNewswire/ — United Therapeutics Corporation (Nasdaq: UTHR) today announced the release of its initial Corporate Responsibility Report with primarily 2019 data and selected 2020 highlights, providing stakeholders important information regarding the company’s commitment to environmental, social, and governance (ESG) priorities.

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Bioinformatics Pharmaceutical Companies DNA Government 40

The Pharma Data

JANUARY 13, 2021

” The Johnson & Johnson vaccine also would be hardier than either of the already approved vaccines because it relies on DNA technology rather than messenger RNA to prompt an immune system response. If you only have to give one dose, that would be great.” The pharmaceutical giant pledged in its $1 billion contract with the U.S.

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Vaccine Trials Clinical Trials Immune Response 40

Drug Target Review

JUNE 11, 2024

My PhD work was focused on understanding how different helicases – small machines that unwind DNA and RNA – work and characterise them using biochemistry and biophysics tools. Governments could also work on educating parents to overcome some unconscious biases, for instance when choosing the toys their kids play with.

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Engineering Science Molecular Biology Doctors 65

LifeSciVC

FEBRUARY 16, 2024

Choosing the wrong candidate from an artificially limited pool is ultimately disruptive and risks imprinting the wrong habits in the company’s DNA. Pushing for a CEO too early may mean constraining your options. Second, at a certain phase of the company, there may not be enough outside leadership required to justify the investment.

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DNA Science Government Production 71

The Pharma Data

OCTOBER 14, 2020

Assistant Professor of Medical Sciences at Columbia University Vagelos College of Physicians and Surgeons, is designed to generate DNA aptamer-based anti-idiotypes to selected monoclonal antibodies identified in Dr. Ilya Trakht’s study. The study led by Dr. Sergei Rudchenko, Ph.D.,

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Vaccine Pharmaceuticals Small Molecule Virus 40

The Pharma Data

SEPTEMBER 1, 2020

In general, antigen tests have a high specificity, though are not as sensitive as molecular tests that amplify the target viral DNA or RNA sequence in order to generate a quantifiable signal to indicate the presence of the virus in a sample.

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Virus Laboratories Clinical Trials Treatment 52

Agency IQ

OCTOBER 12, 2023

In particular, they discussed the potential for genotoxicity, or the potential to damage human DNA, and developmental neurotoxicity, or the negative effect on the developing human nervous system. These experts concluded that there were real concerns regarding the human health risk of chlorpyrifos and CHP-methyl.

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Regulations Animal Testing Government Production 40

The Pharma Data

APRIL 30, 2021

Under the multi-year agreement, AbbVie will utilize Caribou’s next-generation Cas12a CRISPR hybrid RNA-DNA genome editing and cell therapy technologies to research and develop two new CAR-T cell therapies directed to targets specified by AbbVie. AbbVie and Caribou Biosciences, Inc., Full-Year 2021 Outlook.

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FDA Production Treatment International 40

Broad Institute

OCTOBER 4, 2023

Related links Merkin Prize Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Caruthers was announced as the winner in June for his development, in 1981, of an efficient, automated technology for synthesizing DNA.

DNA 52

DNA RNA Science Protein Expression 52

Codon

JULY 10, 2024

In 1952, when the famous Hershey-Chase experiment indicated that DNA—and not protein—was the source of genetic material, just 285 papers mentioned E. But most discoveries today are made by transforming cells—literally coaxing microbes to take up foreign DNA—to add, remove, or edit genes.

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Laboratories DNA Molecular Biology Engineering 86

PLOS: DNA Science

AUGUST 22, 2024

It might seem minor, just a few pages, but the entire subplot of a nefarious government cover-up of a biotech disaster unfurls from it. In the 1940s, army scientists at a government facility in Fort Detrick, Maryland, began testing chemicals for use as defoliants. The DNA double helix is exquisitely symmetrical. BUT WAIT!!!

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DNA Virus Organic Chemistry Science 68

The Pharma Data

AUGUST 3, 2020

Thousands of DNA test machines will be rolled out in hospitals from September. The “on-the-spot” swab and DNA tests will help distinguish between Covid-19 and other seasonal illnesses, the government said. The government has also not published full details on the accuracy of the tests. Image caption.

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Government DNA Hospitals Laboratories 52

PLOS: DNA Science

SEPTEMBER 21, 2023

Speakers hail from biobanks, industry, academia, government, health care systems, and tech centers and institutes. What steps should researchers take when attempting to acquire DNA samples from modern descendants? The post The Festival of Genomics and Biodata 2023 Comes to Boston appeared first on DNA Science.

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DNA Science Medical Schools Government 52

Codon

APRIL 19, 2023

government found out about it. A lawsuit alleged that Black’s company had failed “to disclose substantial payments to officials of foreign governments in order to secure favorable treatment.” deposed a democratically-elected government in Guatemala at the behest of the same company.) has a genome made of DNA.

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DNA RNA Engineering Regulations 52

Codon

APRIL 19, 2023

government found out about it. A lawsuit alleged that Black’s company had failed “to disclose substantial payments to officials of foreign governments in order to secure favorable treatment.” deposed a democratically-elected government in Guatemala at the behest of the same company.) has a genome made of DNA.

DNA 52

DNA RNA Engineering Regulations 52

The Pharma Data

AUGUST 3, 2021

price performance in the second quarter of 2021, as increased utilization in more highly-rebated government segments was offset by lower utilization in the 340B segment, primarily for the diabetes portfolio. and international governments and near-term expiry dates of COVID-19 antibodies. The increase in U.S. Revenue outside the U.S.

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Production Marketing Research DNA 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

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DNA Therapies Engineering Clinical Trials 52