Remove DNA Remove Immune Response Remove Targeted Protein Degradation
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Antibody-drug conjugates payloads: then, now and next

Drug Target Review

2 In response, DNA-damaging agents that could target the entire cell cycle received renewed attention as ADC payloads. More recently, researchers have begun to look at conjugating immunomodulatory agents to antibodies to directly activate an immune response against the tumour. Florian S, Mitchison TJ. Chang, P. &