The Pharma Data

NOVEMBER 22, 2021

Located within the Cambridge Biomedical Campus1, the physical propinquity of the structure’s m2 laboratories to leading hospitals, the University of Cambridge, other exploration institutions and a number of biotech companies will promote a culture of open cooperation and invention in its inviting open spaces.

Molecular Biology 52

Molecular Biology Laboratories Engineering Hospitals 52

Broad Institute

MAY 14, 2024

William Studier for development of widely used protein- and RNA-production platform The $400,000 award recognizes the far-reaching medical impacts of Studier’s development, in the 1980s, of an efficient and scalable technology to produce mass amounts of RNA and proteins in laboratories that is widely used today all over the world.

RNA 84

RNA Production Molecular Biology Laboratories 84

Drug Discovery World

AUGUST 3, 2023

Susan Audino is ISO Assessor and Instructor, Scientific Advisor at AOAC International CASP, and Chemistry Laboratory Consultant at SA Audino & Associates, LLC. 12 Cristina Sanchez, Associate Professor of Biochemistry and Molecular Biology, School of Biology, Complutense University, was featured as a Plant Science Pioneer.

Clinical Trials 130

Clinical Trials Regulations Production FDA 130

Drug Discovery World

NOVEMBER 15, 2022

Here we outline four synthetic biology approaches that are improving and accelerating drug discovery: . Rapid and accurate DNA synthesis . As such, the synthesis of DNA oligonucleotides for routine molecular biology applications is often outsourced to service provider companies that operate DNA synthesisers to meet these demands.

DNA 246

DNA Engineering Drugs Vaccine 246

Codon

JUNE 25, 2024

However, they plod along as they clone plasmids—the loops of DNA that biologists use to manipulate and study organisms—because propagating them relies, in part, on the pace at which cells grow and divide. Most medicines, including insulin and semaglutide (the weight loss drug), are made using DNA cloning. However, E.

DNA 70

DNA RNA Laboratories Engineering 70

sptlabtech

JUNE 9, 2023

However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space. Enter firefly ®. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Laboratories 89

Laboratories Molecular Biology DNA Engineering 89

sptlabtech

JUNE 9, 2023

However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

Molecular Biology 52

Molecular Biology DNA Laboratories Production 52

The Open Targets Blog

APRIL 25, 2023

Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. Only later were the first computers established to automate intelligence gathering.

DNA 52

DNA Government Engineering Laboratories 52

Codon

JULY 11, 2023

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 64

RNA DNA Engineering Laboratories 64

Codon

JULY 11, 2023

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 52

RNA DNA Engineering Laboratories 52

Drug Discovery World

NOVEMBER 9, 2023

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. Phil Leighton, PhD, Senior Director, Molecular Biology, OmniAb, on: ‘Heavy chain-only transgenic chickens produce human antibodies with robust immune repertoires and high-affinity binding’.

Engineering 130

Engineering Therapies Protein Production Science 130

Drug Discovery World

OCTOBER 25, 2023

However, the ligation step is biased and inefficient because the enzymes that ligate the adapters, which are DNA and RNA sequences, prefer some sRNAs that the adapters are ligated to. DDW Volume 24 – Issue 4, Fall 2023 Biography: Darrell Green is a lecturer and Group Leader in RNA Biology at Norwich Medical School, University of East Anglia.

Bioinformatics 287

Bioinformatics Pharmacogenetics RNA Medical Schools 287

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here. From Ling B et al.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. billion units of DNA code are transcribed into more than a hundred volumes, each a thousand pages long, in type so small as to be barely legible.” You can read all of them here. From Ling B et al.

Therapies 52

Therapies RNA DNA Engineering 52

Drug Discovery World

OCTOBER 11, 2023

Additionally, drugs like quinolones and rifampin disrupt the synthesis of nucleic acids, which are essential for bacterial DNA replication. Dr Clifton has developed novel bio-membrane sample systems which have been used to answer applied questions of membrane biology.

Protein Production 147

Protein Production Pharmaceutical Companies Production DNA 147

Codon

APRIL 2, 2024

in physics at Princeton University, he had a remarkable idea: What if it were possible to build a circuit out of DNA, rather than electronics, and use it to “program” a living cell? But in those early years, everything in the laboratory was so slow and difficult. In 1997, as Michael Elowitz was studying for a Ph.D.

RNA 56

RNA Engineering Molecular Biology Synthetic Chemistry 56

Codon

JUNE 18, 2024

These algae are “one of the most interesting, at least one of the most striking, of the plankton,” wrote Klebahn, who transported the cells back to his laboratory in Hamburg, one hundred kilometers to the south. Light and Sound Progress in biology has long been driven by light. ” During his Ph.D., up to 17 MHz.

Engineering 66

Engineering Laboratories International Clinical Trials 66

BMG Labtech

MARCH 8, 2023

DNA, proteins, polysaccharides, etc.). They are strongly oxidizing and, at high concentrations, are deleterious to cells damaging DNA, proteins and lipids, and eventually leading to cell death. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press. nucleotides, monosaccharides, etc.), doi:10.1101/glycobiology.3e.005

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

Codon

JULY 10, 2024

But in the 1950s, at the dawn of molecular biology, scientists gained a new appreciation for it after searching for organisms that were easy to work with and quick to grow. In 1952, when the famous Hershey-Chase experiment indicated that DNA—and not protein—was the source of genetic material, just 285 papers mentioned E.

Laboratories 76

Laboratories DNA Molecular Biology Engineering 76

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52