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Machine learning guides researchers to new synthetic genetic switches

Broad Institute

What is special about these synthetically designed elements is that they show remarkable specificity to the target cell type they were designed for," said Ryan Tewhey, an associate professor at The Jackson Laboratory and co-senior author of the work with Steven Reilly of Yale, and Pardis Sabeti of the Broad. In a paper published in Oct.

Research 136
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Logistics in Focus: Orchestrating the Challenges of Cell Therapy

Conversations in Drug Development Trends

For example, once considered incurable and terminal, patients with sickle cell disease may reach new summits in their lives with gene editing technologies such as CRISPR to repair affected DNA and, in some cases, functionally cure the condition. These advanced therapeutics harness the power of molecular biology to improve human health.

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Empowering scientists in the genomic revolution

sptlabtech

However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space. Enter firefly ®. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

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Liquid Handling - Empowering scientists in the genomic revolution

sptlabtech

However, with so many individual processes involved in NGS library preparation, you might think that automating this workflow requires several instruments costing large amounts of laboratory space. What benefits can you expect to see from making the switch to automated liquid handling with firefly?

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Phages could help to tackle antimicrobial resistance

Drug Target Review

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. Its presence elsewhere would indicate something is wrong. But what, exactly?”

RNA 59
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Q&A With Dr. Norbert Makori and Pierre Jolicoeur: The Benefits of Combining Preclinical and Bioanalytical for Your Gene Therapy Studies

Alta Sciences

PJ: At Altasciences, we have a range of leading-edge platforms that include ligand binding assays (LBA), NAb, TAb, flow cytometry, and ELISpot, as well as on-site molecular biology instrumentation such as Bio-Rad’s ddPCR system, the NanoDropTM One spectrophotometer, and dedicated polymerase chain reaction (PCR) chambers.

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Trends & Insights: Spotlight Winter Edition

DrugBank

Check out previous Trends & Insights Spotlights Academic User Spotlight Subhajit Dutta 1,2 & Ted Natoli 3 Laboratory of Cellular Differentiation & Metabolic Disorder, Department of Biotechnology, National Institute of Technology Durgapur, India. 2 Cancer Program, Broad Institute of MIT and Harvard, USA.