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SARS-CoV-2: advancing the production of the ACE2 protein

Drug Target Review

Researchers from Columbia University and the US Department of Energy (DOE)’s Brookhaven National Laboratory have elucidated a method to produce large quantities of the receptor that the SARS-CoV-2 spike protein uses to bind to the surface of human cells.

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Addressing increasingly resistant drugs by infectious agents

Drug Target Review

Infectious agent includes bacteria, virus, fungi, and parasites, and they are capable of causing disease in a living organism. I had earlier proposed the use of Palmatine and Silver Nitrate in the efficacy against the RNA structure of the COVID-19 virus. He has over two years of experience in research and laboratory work.

Drugs 111
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A therapy candidate for fatal prion diseases turns off disease-causing gene

Broad Institute

By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. They used an engineered adeno-associated virus (AAV) that crosses the blood-brain barrier after intravenous administration. Credit: Neumann EN, Bertozzi TM, et al.

Disease 142
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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. They will present on expression and characterisation of novel GCN-related N-acetyltransferases by Nucleras rapid protein assess system. The session ends with two presentations and two luncheon presentations.

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Codon Digest: CAR-T Therapy for Neuroblastoma

Codon

Marine sponges were cultured in the laboratory continuously for the first time. ” This technology could be used to design protein therapeutics that can bind to, and “shut down,” harmful or misfolded proteins in living cells. The RNA strands shut down a specific gene in the insects, and killed half after 7 days.