Codon

DECEMBER 17, 2023

Recombinant DNA technologies were invented in the 1970s. Today we’re launching Asimov Press , a new publishing venture modeled on Stripe Press , that will produce a newsletter, magazine, and books that feature writing about biology. Newsletters and magazines will be free to read.

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Engineering Molecular Biology Doctors DNA 52

Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

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Therapies DNA Virus Clinical Trials 138

Codon

MARCH 12, 2023

“The recombinant DNA breakthrough has provided us with a new and powerful approach to the questions that have intrigued and plagued man for centuries. The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. Biology is a Burrito. 6 of 31.

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DNA Engineering RNA Therapies 52

PLOS: DNA Science

AUGUST 10, 2023

Ironically, while I was reading The Covenant of Water , the cover story of the July 23 New York Times magazine featured The Vanishing Family , by Robert Kolker. The post The Covenant of Water by Abraham Verghese: A Geneticist’s Review appeared first on DNA Science. It is an unforgettable book. Thank you, Dr. Verghese.

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Disease DNA Doctors Hospitals 74

Codon

MAY 30, 2023

This week: A way to measure a transgene’s expression in the brain using ultrasound, a DNA sequencing method that uses 1000x less reagents, and base editors get even smaller. An engineered version of this protein can convert DNA bases with efficiencies up to 92%. so this Digest will be published more irregularly.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

This week: A way to measure a transgene’s expression in the brain using ultrasound, a DNA sequencing method that uses 1000x less reagents, and base editors get even smaller. An engineered version of this protein can convert DNA bases with efficiencies up to 92%. so this Digest will be published more irregularly.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MARCH 24, 2024

Water accounts for 70 percent of a bacterium by mass; the other 30 percent includes everything else: proteins, RNA, DNA, lipids, and so on. If the technology proved successful in human beings, it would take Moderna weeks, not years, to make a new product,” wrote Catherine Elton in Boston Magazine.

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Engineering Vaccine Production RNA 87

Codon

MARCH 26, 2023

Link A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth. Link DNA storage in thermoresponsive microcapsules for repeated random multiplexed data access. Link Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency. Quanta Magazine.

DNA 52

DNA Engineering RNA Small Molecule 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

DNA sequences are designed on a computer, and it takes a dozen or more clicks to change a single nucleotide. DNA sequences are also checked by hand, so it’s easy to make a mistake. The tool outputs a DNA sequence that encodes all the required enzymes. Anyone who has tried to engineer a cell knows how tedious it can be.

DNA 52

DNA Therapies Engineering Clinical Trials 52

PLOS: DNA Science

MAY 2, 2024

Will an effort to determine the sex chromosome constitutions of nearly 600,000 men whose DNA is being analyzed in the Million Veteran Program provide helpful health information – or highlight another possible source of genetic judgment? appeared first on DNA Science. Of twelve men with unusual chromosomes, seven had an extra Y.

DNA 52

DNA Engineering Hospitals Disease 52

Codon

AUGUST 10, 2023

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

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DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 23, 2023

The country has now ruled that the gene-edited bananas are exempt from GMO regulations because they do not carry additional DNA sequences, and so they will not have to pass through strict safety testing. 📎 Papers Strands of DNA can be used to build molecular logic gates. ” Quanta Magazine. Nature Communications.

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Vaccine DNA Virus Engineering 52

Codon

APRIL 23, 2023

The country has now ruled that the gene-edited bananas are exempt from GMO regulations because they do not carry additional DNA sequences, and so they will not have to pass through strict safety testing. 📎 Papers Strands of DNA can be used to build molecular logic gates. ” Quanta Magazine. Nature Communications.

Vaccine 52

Vaccine DNA Virus Engineering 52

Codon

APRIL 16, 2023

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? coli DNA using a Retro-Cascorder.

Engineering 52

Engineering DNA RNA Science 52