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Tech Focus: How is HTS accelerating early-stage drug discovery?

Drug Discovery World

For example, multiple RNA helicases are being targeted for cancer and viral infections before their catalytic properties are well understood. According to the company, the dual-recognition, DNA-coupled technology offers high specificity, reducing the risk of wrong targets. appeared first on Drug Discovery World (DDW).

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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This week: A way to measure a transgene’s expression in the brain using ultrasound, a DNA sequencing method that uses 1000x less reagents, and base editors get even smaller. An engineered version of this protein can convert DNA bases with efficiencies up to 92%. so this Digest will be published more irregularly.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This week: A way to measure a transgene’s expression in the brain using ultrasound, a DNA sequencing method that uses 1000x less reagents, and base editors get even smaller. An engineered version of this protein can convert DNA bases with efficiencies up to 92%. so this Digest will be published more irregularly.

DNA 52
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Codon Digest: Moore's Law

Codon

Link Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Link U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes. Link A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth. Link Probing metabolism in an E. Mimoso C.A.

DNA 52
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Codon Digest: GPT-4 Controls a Robot

Codon

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? coli DNA using a Retro-Cascorder.