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Re-Imagining Med Chem Strategies: the Tyranny of the n+1 Compound

DrugBaron

A lot of resources are therefore poured into synthetic chemistry, and if the compound family is at all synthetically challenging it can require dozens, even hundreds, of chemists to churn out every imaginable variant. Not just more data per week. Definitely not just more compounds per week. More answers.

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Synthetic Origins

Codon

in physics at Princeton University, he had a remarkable idea: What if it were possible to build a circuit out of DNA, rather than electronics, and use it to “program” a living cell? For the next three years, working with advisor Stanislas Leibler, Elowitz labored over this synthetic gene circuit and achieved precisely that.

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