DNA, Protein Expression and Protein Production

Proteogenomics reveals markers of chemotherapy resistance and outcome in triple negative breast cancer

Broad Institute

AUGUST 24, 2022

Data from standard DNA and RNA sequencing approaches were integrated with mass spectrometry-based proteomics and phosphoproteomic analyses to derive more complete molecular portraits of treatment-responsive versus treatment-resistant tumors. These data suggest a multi-omics predictor for chemotherapy response is within reach.

DNA

DNA Protein Expression Treatment Protein Production

Key considerations before commencing cell line development

Drug Target Review

JULY 5, 2023

A good introduction to the use of CHO cells for biotherapeutics production can be found in an article commemorating the 20th anniversary of the approval of a product produced using CHO cells. These sites are typically in areas of open chromatin and associated with highly expressed genes. Biotechnol. 2022), 349: 53-64.

Engineering

Engineering DNA Laboratories Production

Drug Discovery Digest

Proteogenomics reveals markers of chemotherapy resistance and outcome in triple negative breast cancer

Key considerations before commencing cell line development

Webinars

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