Drug Discovery World

APRIL 17, 2024

Increasing gene expression via protein replacement or gene therapy has been shown to have limitations and drawbacks. CAMP4 is the only company modulating gene expression at the transcriptional level to increase mRNA production and thereby increase healthy protein production.

Science 148

Science RNA Disease Protein Expression 148

Drug Discovery World

APRIL 30, 2024

Reece Armstrong explores the potential and future opportunities for mRNA-based therapies. For instance, consider how at the end of 2018, the mRNA therapies market was valued at $3.43 mRNA-based approaches can produce proteins / peptides by using protein synthesis which is processed in a transfected cell 1.

Therapies 130

Therapies RNA Vaccine Small Molecule 130

Drug Discovery World

NOVEMBER 9, 2023

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. These include: Samantha Bailey-Bucktrout, PhD, Senior Vice President, Akamis Bio, on: ‘Tumour specific immunogene therapy to deliver protein therapeutics to solid tumour microenvironments’.

Engineering 130

Engineering Protein Production Therapies Science 130

Drug Discovery World

NOVEMBER 30, 2023

This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It It was by Nicholas Field, Principal Scientist, Purification Development, Lonza, titled: ‘Tailored CMC solutions to overcome the challenges in bispecific, Fab and Fc-fusion protein development programs’.

Protein Expression 148

Protein Expression Engineering DNA Therapies 148

Drug Discovery World

NOVEMBER 13, 2023

Christopher Rowley, PhD, Principal Research Scientist, Protein Science Pipeline, Immunocore, on: ‘ImmTAC: A high-affinity soluble TCR bispecific platform to target cancers’. Jürgen Kuball, PhD, Head, Hematology, University Medical Center Utrecht, on: ‘gdT cell inspired therapies’.

Engineering 148

Engineering Science Bioinformatics Vaccine 148