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Researchers teach AI to tailor artificial DNA for drug development

Drug Discovery World

Using artificial intelligence, researchers at Chalmers University of Technology, Sweden have succeeded in designing synthetic DNA that controls the cells’ protein production. . The technology can contribute to the development and production of vaccines and drugs for severe diseases much faster and at lower cost.

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SLAS2023: We have the building blocks, onto the building

Drug Discovery World

How can technology help drug discovery research get to market faster and at optimum efficiency? Using AI, researchers at Chalmers University of Technology, Sweden succeeded in designing synthetic DNA that controls the cells’ protein production.

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Cave Coronavirus in Wuhan Lab Seeded COVID – The Truth Has Always Been Out There, in the Genetics

PLOS: DNA Science

The virus SARS-CoV-2 emerged in Wuhan, home of a premiere research institute that focuses on viruses. A year before the initial outbreak, Wuhan researchers proposed nurturing a coronavirus with enhanced ability to attach onto, and enter, human cells. Her points: 1. Shortly thereafter, some workers became sick. Coincidence?

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Turning science into business: Amplifying mRNA by targeting regRNAs

Drug Discovery World

DS: CAMP4 leverages research from co-founder Richard Young on how regulatory RNA (regRNA) molecules control the expression of genes. JMB: Regulatory RNAs (or regRNAS) are molecules that directly control the expression of nearby protein-coding genes. DS: How easy was it to transfer theoretical research into a viable business?

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Proteogenomics reveals markers of chemotherapy resistance and outcome in triple negative breast cancer

Broad Institute

Credit: NCI ) Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard, and Washington University in St. The team then conducted analyses that triangulated treatment response, chromosomal deletion or gain, and concordant decreases or increases in mRNA and protein expression.

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Global advances in synthetic biology

Drug Discovery World

Applying the principles of engineering to biology – redesigning organisms and biological parts to create synthetic components with new abilities – fuels the progression of medicine and gives researchers additional ability to tackle scientific issues. . Brady and colleagues turned to algorithms.

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A Look Back

Dark Matter Blog

As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. Growing up in Shrewsbury, Massachusetts, it was natural for me to attempt to get a summer job up the road at the Worcester Foundation for Biomedical Research, where the first oral contraceptive was created. I wanted to use molecular biology to create drugs.