Remove DNA Remove Small Molecule Remove Targeted Protein Degradation
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Antibody-drug conjugates payloads: then, now and next

Drug Target Review

2 In response, DNA-damaging agents that could target the entire cell cycle received renewed attention as ADC payloads. Groundbreaking strategies like proteolysis-targeting chimeric molecules (PROTACs) are also being explored. DNA damaging agent-based antibody-drug conjugates for cancer therapy. Chang, P. &