Drug Discovery World

JULY 29, 2022

Isselbacher Professor of Medicine in the Field of Gastroenterology at Harvard Medical School and Massachusetts General Hospital, a core institute member at the Broad Institute of MIT and Harvard, and co-director of the Center for Microbiome Informatics and Therapeutics at MIT. Study after study had suggested that A. Funding and authorship.

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KIF1A

AUGUST 20, 2024

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. One day later, we arrived at the hospital. A cheek swab DNA test was performed at the hospital, which also resulted as normal. Pauline born weighing 2.645 kg and measuring 45 cm.

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Broad Institute

OCTOBER 3, 2024

The findings point to factors involved in how neurons communicate and fire, suggesting potential targets for new therapies. In the future, the results could also help doctors tailor treatments to a patient’s genome. Epilepsy is one of the most common neurological disorders.

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Drug Target Review

JANUARY 12, 2024

This one size fits all approach to drug prescribing still pervades in mostly all therapy areas except oncology. Therefore, having biomarker information is useful for separating individuals and ensuring that you treat an individual as an individual and can tailor their therapy. Most drugs do not work in all people.

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The Pharma Data

OCTOBER 22, 2020

22, 2020 — Kids with autism or attention-deficit hyperactivity disorder ( ADHD ) go to the hospital more in their first year of life than children without these conditions, according to a new study. ” For the study, the researchers examined 10 years of data from electronic health records of nearly 30,000 children.

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biobide

FEBRUARY 2, 2024

Children and adolescents lack robust preclinical models to replicate the pathologies and provide precise and targeted therapies. This is why not many Pharma companies specifically specialize in discovering and developing pediatric cancer treatments; a great example of advancing new therapies for childhood cancer is the biotech Oncoheroes.

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Drug Target Review

JANUARY 23, 2024

Cell-based therapies, such as tumour-infiltrating lymphocyte (TIL) therapy, have also drawn significant attention following promising results in a melanoma trial. Researchers have been characterising the tumour immune microenvironment (TIME) to better understand anti-cancer immunity and resistance to immunotherapy.

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PLOS: DNA Science

OCTOBER 3, 2024

A research team led by Rita Fior at the Champalimaud Centre for the Unknown, Lisbon, Portugal, figured out how BCG decimates cancer cells. He and other doctors who used them reported excellent results, especially in bone and soft-tissue sarcomas. Because research is very active in this field, William B. The approach worked.

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The Pharma Data

NOVEMBER 20, 2020

20, 2020 — Hormone therapy can be a lifesaver for men with prostate cancer , but it also appears to put some at increased risk of heart problems, a new study reports. “Our data are not suggesting that androgen deprivation therapy definitely causes worse heart health,” said lead researcher Dr. . FRIDAY, Nov.

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The Pharma Data

JUNE 1, 2022

has been appointed Senior Vice President and Head of the Company’s Vaccine Research & Development (R&D) organization effective August 1, succeeding Kathrin U. Chief Scientific Officer and President, Worldwide Research, Development and Medical of Pfizer. “I (NYSE: PFE) today announced that Annaliesa Anderson, Ph.D.,

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Drug Target Review

DECEMBER 28, 2023

In most cancers, the tumour evolves by acquiring mutations that confer growth advantages or resistance to therapies. Involving more than 250 investigators based at 19 hospital sites across the UK, the study has analysed genetic signatures in lung tumours, tracking how they have evolved over the past nine years in more than 815 patients.

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Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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Drug Target Review

FEBRUARY 26, 2024

Regarding therapy resistant melanomas, why is the alteration of the epigenetic landscape considered significant, and what has been lacking in terms of validated targetable epigenetic mechanisms? What is remarkable here is that we show that the addition of corin to BRAFi-resistant tumour cells resensitises them to BRAFi therapies.

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Broad Institute

JULY 26, 2022

Researchers decipher how a gut bacterium influences immunity By Corie Lok July 26, 2022 Breadcrumb Home News Researchers decipher how a gut bacterium influences immunity Study finds a molecule made by the bacterium that helps moderate immune responses. Study after study had suggested that A. muciniphila ’s cell membrane.

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PPD

MAY 18, 2023

For neurodegenerative disease research, the care partner, or caregiver, is equally important as the person with dementia. The care partners are the decision-makers for their loved ones with neurodegenerative disorders, handling everything from daily routines and medication management to doctor visits.

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Olympian Clinical Research

OCTOBER 14, 2021

The more participants there are, the easier it will be for researchers and doctors to determine what works and what doesn’t work in real world conditions. When you join a clinical trial, you’ll be assigned to a team of doctors and researchers who will monitor your health very closely.

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The Pharma Data

AUGUST 3, 2021

A recent trial showed a significantly lower risk with empagliflozin of hospitalization for heart failure or cardiovascular death in adult patients with HFpEF. We see that in a lot of countries, people avoid seeing their doctors because of COVID-19, even if they are in urgent need of diagnosis and treatment.

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The Pharma Data

JANUARY 21, 2021

Italian researchers found that among 210 multiple sclerosis (MS) patients who received a stem cell transplant — with cells from their own blood — two-thirds saw no worsening in their disability 10 years out. It requires a long hospital stay, plus a period of months when patients are severely immunocompromised, Bebo said.

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Drug Discovery World

OCTOBER 18, 2022

Companies specialising in oncology R&D and therapeutics continue tospring up all around the globe, often spun out of universities working on the latest research. ETH Zurich is ranked in the world’s top 10 universities 1 and as such, receives substantial funding for research, which attracts some of the best minds from around the globe.

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Drug Target Review

JUNE 17, 2024

Could you share an example of a specific project or research that you have worked on and the impact it has had in your field? I was very pleased to be heavily involved with one of the very first radiopharmaceutical therapy programs for patients with neuroendocrine tumours (NETs) nearly two decades ago.

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Drug Discovery World

JUNE 5, 2023

Meet the biotech: Enhanc3D Genomics Enhanc3D Genomics was spun out from the laboratories of Dr Stefan Schoenfelder and Professor Peter Fraser, who pioneered research into the dynamic spatial organisation of the genome at the Babraham Institute in Cambridge, UK.

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FDA Law Blog: Biosimilars

OCTOBER 10, 2023

Dr. Beitz served in leadership positions in FDA’s Center for Drug Evaluation and Research for nearly three decades. Beitz earned a Bachelor of Arts (summa cum laude and honors in chemistry) from Barnard College, Columbia University, and a Doctor of Medicine from the College of Physicians and Surgeons, Columbia University.

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The Pharma Data

JANUARY 15, 2021

Right now, no medication is approved specifically for pulmonary hypertension caused by ILD, said Dr. Steven Nathan, senior researcher on the new trial. He’s director of the Advanced Lung Disease and Lung Transplant Program at Inova Fairfax Hospital in Falls Church, Va. He said the new findings should be enough for the U.S.

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The Pharma Data

JULY 22, 2021

We believe patients, family members and physicians deserve the facts about the therapy and the process by which it was approved so they may make informed decisions. The approval of ADUHELM by the U.S. Food and Drug Administration (FDA) came after an extensive development, testing and review process.

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The Pharma Data

FEBRUARY 1, 2021

1, 2021 — For some patients suffering from knee arthritis, a special procedure may reduce the need for a total knee replacement, Canadian researchers say. He also said that whether a patient is offered a high tibial osteotomy depends on the doctor the patient sees. MONDAY, Feb. So why bother?” ” Birmingham said.

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The Pharma Data

JANUARY 17, 2021

The treatment could be administered in primary care centers to people who test positive for COVID-19, avoiding hospitalization due to the progression of the disease and complementing the vaccine in the early phase after vaccination. BARCELONA, Spain , Jan. 18, 2021 /PRNewswire/ — Grifols (MCE: GRF, MCE: GRF.P,

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The Pharma Data

SEPTEMBER 1, 2021

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. The research team’s ultimate aim is to develop therapies for people coping with rheumatoid arthritis, a debilitating condition that affects about 1.3

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The Pharma Data

JANUARY 6, 2021

Two boys, a 23-month-old and a 6-year-old, developed lung cancers that proved an exact genetic match to cervical cancers within their mothers at the time of birth, Japanese researchers report. Ayumu Arakawa, a pediatric oncologist with the National Cancer Center Hospital in Tokyo. “I found it fascinating, personally. .

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The Pharma Data

NOVEMBER 3, 2020

3, 2020 — Nerve damage to vocal cords could be the reason why some people recovering from COVID-19 suffer mysterious bouts of shortness of breath for months after shaking off the coronavirus, researchers say. Previous research has shown that a vagus nerve injury can cause the vocal cords to fail to retract, impeding air flow.

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The Pharma Data

JANUARY 27, 2021

Researchers found that a three-month cardiac rehabilitation program improved fitness levels and muscle strength in 24 stroke survivors. While the study was small, the researchers said it offers evidence of what’s intuitive: People recovering from a stroke benefit from regular, structured exercise. WEDNESDAY, Jan.

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The Pharma Data

FEBRUARY 12, 2022

Researchers around ISTA professor Daria Siekhaus are now contributing to a better understanding of the process in certain types of cancer. Thus, the researchers performed a stress test on cancer cells with and without the protein. To optimize therapy for their patients, doctors are already analyzing the expression of certain genes.

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The Pharma Data

FEBRUARY 12, 2022

Doctors call this drug ‘bari,’ and receiving the pill once a day for up to 14 days yielded one of the largest a survival advantages seen yet in the COVID pandemic, according to a study published in The Lancet Respiratory Medicine. . “At 60 days, 62% of patients given placebo had died versus only 45% of those receiving bari.

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NIH Director's Blog: Drug Development

APRIL 2, 2020

After confirmation by further research, these maps may well provide a basis for the design and development of therapeutics that specifically target this critical interaction. This is of particular concern to doctors whose patients are already taking the medications to control hypertension. The team, led by Scott D.

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The Pharma Data

JANUARY 20, 2021

The approval of Verquvo by the FDA, which is the first treatment for chronic heart failure approved specifically for patients following a hospitalization for heart failure or need for outpatient IV diuretics, is based on the results of the pivotal Phase 3 VICTORIA trial and follows a priority regulatory review. Verquvo (vericiguat) 2.5

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The Pharma Data

NOVEMBER 17, 2020

Right now, the standard first-line treatment is medication, said Dr. Jason Andrade, lead researcher on one of the new studies. It’s a minimally invasive procedure in which doctors use heat or cold to destroy bits of heart tissue that are generating the faulty electrical signal causing the arrhythmia.

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The Pharma Data

MAY 15, 2021

If You or Someone You Love is Suffering From Chronic Fatigue Syndrome, Then This Will Be the Most Important Letter You Will Ever Read… “Doctors Told Me There Was No Cure For Chronic Fatigue Syndrome…But Contrary To Their Prediction, I Got My Life Back From My CFS…100% Naturally! Description: ATTENTION!

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The Pharma Data

OCTOBER 21, 2020

“I’m not surprised that they could see similar effects of therapy with patients using telemedicine as they would via in person,” said Dr. Andrew Southerland, an associate professor of neurology and public health sciences at University of Virginia Health, in Charlottesville, Va.

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