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Researchers design genetic therapy to prevent brain deterioration

Drug Discovery World

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified potential treatments for children with rare genetic conditions. The researchers have shown that problems with calcium underlie these progressive diseases.

Therapies 147
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Immuno-oncology innovations redefining cancer treatment in 2024

Drug Target Review

What innovative approaches and technologies are anticipated to reshape immuno-oncology treatments in 2024? Immuno-oncology, notably through checkpoint inhibitors, has significantly reshaped cancer treatment over the past decade.

Treatment 122
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Researchers uncover genetic factors for severe Lassa fever

Broad Institute

Researchers uncover genetic factors for severe Lassa fever By Allessandra DiCorato February 8, 2024 Breadcrumb Home Researchers uncover genetic factors for severe Lassa fever New findings from an international collaboration pave the way for studies of highly infectious diseases in Africa such as Ebola.

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With retinal images and genetic data, researchers predict cardiovascular, metabolic, and other disease risks

Broad Institute

This could potentially help with disease prevention — if we know from someone’s retinal image that they are at high risk of developing glaucoma or cardiovascular disease in the future, we could refer them for follow-up screening or preventative treatment.”

Disease 124
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Largest-ever genetic study of epilepsy finds possible therapeutic targets

Broad Institute

Largest-ever genetic study of epilepsy finds possible therapeutic targets By Ari Navetta October 3, 2024 Breadcrumb Home Largest-ever genetic study of epilepsy finds possible therapeutic targets Scientists have uncovered new genetic links to different types of epilepsy, which could lead to more tailored treatments.

DNA 72
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Pauline’s Superhero Story

KIF1A

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. One day later, we arrived at the hospital. A cheek swab DNA test was performed at the hospital, which also resulted as normal. Treatment is within reach, but there are two obstacles in our way: time and money. You can help.

Doctors 52
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Australian discovery boosts hopes of preventing Type 1 diabetes

Drug Discovery World

Australian researchers based may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold. The findings have been replicated by an independent research group at Novo Nordisk in the United States.

Doctors 130