Drug Target Review

JANUARY 12, 2024

Today, diseases are only what we created as a way of naming disorders, a historic creation from doctors who studied patients that had common symptoms. RWD includes things that are captured in routine care, including diagnosis, the pills prescribed, and the length of hospital stay. AI could have a significant role in data harmonisation.

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Drug Discovery World

SEPTEMBER 5, 2022

The discovery was made by researchers at Washington University School of Medicine in St Louis, Grenoble Alpes University in Grenoble in France, and The University of Texas MD Anderson Cancer Center in Houston. Researchers have found that a chemotherapy drug plus blocking resistance makes the tumours virtually disappear (right).

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The Pharma Data

AUGUST 25, 2020

The model suggests that just 13% of full-time academics would have been available to carry out research during the height of the pandemic. At the peak of the COVID-19 pandemic, clinical research capacity may have been slashed by up to 87% in England, according to a new study led by UCL academics.

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The Pharma Data

SEPTEMBER 29, 2020

He also hears about a trial in the US to test whether prayer can help Covid patients in intensive care. The equipment was generously donated by a company called P4 Technology and the mosque will trial it for a year. He is writing this diary for BBC News and recording from the hospital wards for BBC Radio. Front line diary.

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Alta Sciences

JUNE 27, 2023

Cancer Treatments, Clinical Trials, and the Motivation to Innovate nbartlett Tue, 06/27/2023 - 20:58 Getting to the Heart of Science with Michelle Newby At the heart of science are stories—stories of courage, challenges, successes, lessons, and people. A: I went with the clinical trial. A: I wouldn’t be here without clinical trials.

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biobide

FEBRUARY 2, 2024

How can research boost the discovery of specific therapies for childhood and adolescent cancers? Zebrafish Pioneers Advance in Pediatric Cancer Research and Treatment Increasing the survival rate is the primary goal when screening for cancer drugs. This treatment was developed by performing a chemical screening on zebrafish.

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The Pharma Data

JANUARY 17, 2021

The treatment could be administered in primary care centers to people who test positive for COVID-19, avoiding hospitalization due to the progression of the disease and complementing the vaccine in the early phase after vaccination. BARCELONA, Spain , Jan. 18, 2021 /PRNewswire/ — Grifols (MCE: GRF, MCE: GRF.P,

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Drug Target Review

JANUARY 23, 2024

Cell-based therapies, such as tumour-infiltrating lymphocyte (TIL) therapy, have also drawn significant attention following promising results in a melanoma trial. Researchers have been characterising the tumour immune microenvironment (TIME) to better understand anti-cancer immunity and resistance to immunotherapy.

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The Pharma Data

DECEMBER 3, 2020

Another record-breaking day of COVID-19 hospitalizations and deaths underscored Redfield’s grim warning. The number of people hospitalized for COVID-19 on Wednesday passed 100,000, nearly double the highest point seen last spring. With hospitals filling up in multiple states, the days ahead do appear bleak.

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Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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Olympian Clinical Research

DECEMBER 1, 2022

To help relieve the itching and inflammation associated with plaque psoriasis, your doctor may prescribe a topical ointment or steroid. If you are experiencing generalized pustular psoriasis, contact your doctor immediately, as it may be severe and can lead to serious health complications. Nail Psoriasis. Erythrodermic Psoriasis.

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KIF1A

APRIL 25, 2024

However, we needed to wait for Susannah to finish her trial before we could submit to the FDA for Sloane’s ASO use. March 2024 – The FDA approved the IND, and the administering doctor (Dr. Because this is still very experimental we want to be close to the hospital and the administering physician should we need them.

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Codon

JANUARY 21, 2024

Human challenge trials were an indispensable part of the development of the malaria vaccine, R21/Matrix-M, endorsed by the World Health Organization last October. But for all of their benefits, human challenge trials have their drawbacks. Jake himself has participated in both Zika and Shigella challenge trials.

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Drug Discovery World

JUNE 20, 2024

Deepika Khedekar investigates the use of LLMs in clinical trials and how we can overcome the potential challenges to their wider application. Clinical trials make up a large part of this investment, and yet 95% of them fail 2. Hospitals alone are generating 50 petabytes of data every year 4. million data points 5.

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The Pharma Data

SEPTEMBER 2, 2020

The findings confirm the results of an earlier trial, which has already led to steroids being used widely for Covid patients in intensive care. The researchers said the findings were impressive, but stressed steroids were not a coronavirus cure. The studies were on only the sickest hospital patients. Follow James on Twitter.

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The Pharma Data

DECEMBER 17, 2020

COVID-19 vaccine developers are faced with an ethical quandary — whether to let phase 3 trial participants become “unblinded” and to receive authorized vaccines as they become available, which could hinder the collection of meaningful trial data. Pfizer, which has received emergency approvals in the U.S.

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The Pharma Data

AUGUST 3, 2021

A recent trial showed a significantly lower risk with empagliflozin of hospitalization for heart failure or cardiovascular death in adult patients with HFpEF. Progress in mental health pipeline Boehringer Ingelheim also made progress in the area of neuropsychiatric disorders, including two ongoing phase II trials.

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The Pharma Data

JANUARY 25, 2021

Researchers found that when people began using aspirin in their 50s or 60s, their risk of developing colon cancer after age 70 was trimmed by 20%. So the task force — a government-funded panel of medical experts — suggests people in their 60s talk to their doctor about the pros and cons. MONDAY, Jan. More Information.

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The Pharma Data

JULY 22, 2021

Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials. Continued approval for this indication may be contingent upon verification of clinical benefit in confirmatory trial(s). Biogen Inc.

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The Pharma Data

JANUARY 15, 2021

15, 2021 — An inhaled medication might make every day physical activity a bit easier for patients with serious scarring of the lungs, a new clinical trial finds. Right now, no medication is approved specifically for pulmonary hypertension caused by ILD, said Dr. Steven Nathan, senior researcher on the new trial.

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The Pharma Data

OCTOBER 14, 2020

14, 2020 — Older adults who aren’t interested or enthusiastic about their usual activities may have a higher risk of developing dementia , new research suggests. The researchers also had medical records, including medication use, hospitalizations and cognitive testing. WEDNESDAY, Oct. “Apathy is not subtle.

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Drug Discovery World

OCTOBER 18, 2022

Companies specialising in oncology R&D and therapeutics continue tospring up all around the globe, often spun out of universities working on the latest research. ETH Zurich is ranked in the world’s top 10 universities 1 and as such, receives substantial funding for research, which attracts some of the best minds from around the globe.

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The Pharma Data

DECEMBER 11, 2020

. “With the high efficacy and good safety profile shown for our vaccine, and the pandemic essentially out of control, vaccine introduction is an urgent need,” Kathrin Jansen, head of vaccine research and development at Pfizer, told the FDA advisory panel Thursday. Third of Americans live where hospitals are short on ICU beds.

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The Pharma Data

FEBRUARY 12, 2022

Doctors call this drug ‘bari,’ and receiving the pill once a day for up to 14 days yielded one of the largest a survival advantages seen yet in the COVID pandemic, according to a study published in The Lancet Respiratory Medicine. . “At 60 days, 62% of patients given placebo had died versus only 45% of those receiving bari.

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The Pharma Data

NOVEMBER 17, 2020

17, 2020 — A procedure that freezes bits of heart tissue may be a better option than medication for people with atrial fibrillation (a-fib, or AF), two clinical trials have found. Right now, the standard first-line treatment is medication, said Dr. Jason Andrade, lead researcher on one of the new studies. TUESDAY, Nov.

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The Pharma Data

JANUARY 20, 2021

The approval of Verquvo by the FDA, which is the first treatment for chronic heart failure approved specifically for patients following a hospitalization for heart failure or need for outpatient IV diuretics, is based on the results of the pivotal Phase 3 VICTORIA trial and follows a priority regulatory review. 0.98; p=0.019).

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The Pharma Data

AUGUST 20, 2020

Poor regulation of antibodies tests – that could indicate if someone has had coronavirus – could be putting the public at risk, doctors have warned. “For drug licensing the onus is on the companies to go through clinical trials. “For drug licensing the onus is on the companies to go through clinical trials.

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The Pharma Data

JANUARY 21, 2021

Italian researchers found that among 210 multiple sclerosis (MS) patients who received a stem cell transplant — with cells from their own blood — two-thirds saw no worsening in their disability 10 years out. It requires a long hospital stay, plus a period of months when patients are severely immunocompromised, Bebo said.

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The Pharma Data

OCTOBER 19, 2020

There has been some discussion of running challenge trials for COVID-19 vaccines. In a challenge trial, people are given a vaccine then intentionally dosed with the virus or bacteria that causes the disease. Army Medical Research and Development (USAMRDC ) initiated a Phase I clinical trial of its novel vaccine against COVID-19.

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The Pharma Data

DECEMBER 31, 2020

Doctors on the pandemic’s front line say people shouldn’t panic, but should definitely adhere even more closely to proven infection control measures, like mask wearing and social distancing. and abroad,” said Dr. He’s an emergency medicine physician at Lenox Hill Hospital in New York City. THURSDAY, Dec.

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The Pharma Data

SEPTEMBER 1, 2021

1 Relapse was defined as psychiatric hospitalization, increase in Positive and Negative Syndrome Scale [PANSS] total score, increase in individual PANSS item scores, self-injury, violent behavior, or suicidal/homicidal ideation. DFAPA, Medical Director at ATP Clinical Research and 6-month paliperidone palmitate clinical trial investigator.

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The Pharma Data

DECEMBER 4, 2020

That response is facing its toughest challenge so far, as daily case counts, hospitalizations and deaths continue to set records on a daily basis. “If we don’t act now our hospital system will be overwhelmed,” Gov. Doctors say this reflects India’s younger and leaner population. Gavin Newsom said.

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The Pharma Data

MAY 15, 2021

If You or Someone You Love is Suffering From Chronic Fatigue Syndrome, Then This Will Be the Most Important Letter You Will Ever Read… “Doctors Told Me There Was No Cure For Chronic Fatigue Syndrome…But Contrary To Their Prediction, I Got My Life Back From My CFS…100% Naturally! Description: ATTENTION!

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The Pharma Data

JANUARY 6, 2021

None of the cases required an EpiPen injection or hospitalization. We have heard about three incidences that occurred in the Moderna Phase III trial that involved 30,000 patients … so the incidence is very rare,” said Herluf Lund, a cosmetic surgeon in St. None were considered life-threatening. “We It’s a 1 in 10,000 incidence.”.

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The Pharma Data

DECEMBER 2, 2020

Around the world, researchers are testing 57 vaccines in clinical trials, and nearly 100 others are being tested in animals or cells. China and Russia have both approved vaccines without waiting for the results of late-stage trials, which experts say raises safety concerns. Hospitalizations reach record high.

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The Pharma Data

JULY 21, 2021

to reduce the risk of cardiovascular death and heart failure hospitalization following a hospitalization for heart failure or need for outpatient IV diuretics in adults with symptomatic chronic heart failure and ejection fraction less than 45%. In January of this year, the U.S. In the U.S., mg, 5 mg and 10 mg).

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The Pharma Data

NOVEMBER 17, 2020

Coronavirus infections in the state have doubled over the past month, and the number of hospitalized patients reached a new high on Monday. The researchers behind the vaccine said the results were better than they had dared to imagine, though it will probably not be available until spring, the Times reported. effectiveness.

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