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Simple test for flu could improve diagnosis and surveillance

Broad Institute

By Allessandra DiCorato June 18, 2024 Credit: Jon Arizti-Sanz SHINE, a rapid diagnostic test developed by Pardis Sabeti's lab in 2020, uses paper strips and CRISPR enzymes to identify specific sequences of viral RNA in samples. Then, in 2022, they began adapting the assay to detect other viruses they knew were always circulating: influenzas.

Virus 144
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A close research partnership with African scientists helps solve the mystery of malaria-like illnesses

Broad Institute

First author Zoë Levine is an MD-PhD candidate at Harvard Medical School and graduate student in the lab of Pardis Sabeti at the Broad. That’s interesting from a public health perspective because oftentimes in a clinical setting, if someone tests positive for malaria, the doctor will give them antimalarials and stop there.

Research 111
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Battling antibiotic resistance in the lab and the clinic

Broad Institute

Patients with possible undiagnosed infections kept him up at night as he ran through their medical histories, occupations, and personal life details in his mind, searching for clues to the identity of the microscopic invaders. I couldn’t fathom what it was going to be like,” he said.

Hospitals 137
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New “dictionary” of immune responses reveals far more complexity in the immune system than previously thought

Broad Institute

Using single-cell RNA sequencing to analyze gene expression in individual cells, the researchers have found how 86 major cytokines affect 17 immune cell types in mice. Tags: Cell Circuits Program Immunology RNA sequencing The reference, called the Immune Dictionary , appears today in Nature. Did any results surprise you?

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tk

Broad Institute

Cell Painting uses six fluorescent dyes to image eight different components of a cell: the nucleus, nucleoli, mitochondria, endoplasmic reticulum (ER), golgi apparatus, cytoplasmic RNA, f-actin cytoskeleton, and plasma membrane.

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#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Broad Institute

Today, she is a senior associate computational biologist in the Getz lab, where she applies computational techniques to DNA and RNA sequencing data to analyze rapid autopsy samples, taken from multiple sites throughout the body at the time of a cancer patient’s death. I love that in all forms of science, you solve problems.

Science 124
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Pfizer Nears Deal to Provide More COVID Vaccine to Americans

The Pharma Data

One person familiar with the list said it included the lipids that encase the RNA material in both the Moderna and Pfizer vaccines, the Times reported. is so sporadic,” Jeremy Luban, a virologist at the University of Massachusetts Medical School, told the Post. “It may very well be here. The sequencing in the U.S.

Vaccine 52