Drug Target Review

FEBRUARY 29, 2024

Through further research and work as a principal investigator on clinical studies for several central nervous system indications, I laid the groundwork for a career in gene therapy drug development. AskBio) I continue to work to bring innovative gene therapies to patients in need. In my current role at Asklepios BioPharmaceutical, Inc.

Therapies 111

Therapies Disease Clinical Trials Science 111

Broad Institute

JANUARY 25, 2024

“We’ve come to realize recently that there is a lot more information that we can get from our retina images than we thought was possible,” says senior author Nazlee Zebardast, director of glaucoma imaging at Mass Eye and Ear and an assistant professor of ophthalmology at Harvard Medical School.

Disease 124

Disease Research Science Medical Schools 124

Drug Target Review

MARCH 15, 2024

He has a post-doctorate in virology, viral pathogenesis, viral vector development, and vaccines evaluation from Harvard Medical School, and a PhD in virology/molecular biology. Cell Gene Therapy Insights 2017; 3(2), 131-158, 10.18609/cgti.2017.014. Biotechnol Prog. 2017 Nov;33(6):1468-1475. doi: 10.1002/btpr.2548.

Engineering 105

Engineering Molecular Biology Protein Expression Medical Schools 105

Broad Institute

JANUARY 30, 2024

Patients with possible undiagnosed infections kept him up at night as he ran through their medical histories, occupations, and personal life details in his mind, searching for clues to the identity of the microscopic invaders. I couldn’t fathom what it was going to be like,” he said.

Hospitals 137

Hospitals Medical Schools Virus Science 137

Broad Institute

OCTOBER 23, 2024

The work highlights the importance of examining the often-ignored noncoding parts of the genome when diagnosing rare genetic disorders, and also points to possible future genetic therapies that fine-tune CHASERR abundance as a means to treat CHASERR - and CHD2 -related disorders.

DNA 128

DNA RNA Disease Hospitals 128

Broad Institute

JULY 26, 2022

By Stephanie Dutchen, Harvard Medical School Office of Communications and External Relations July 26, 2022 Credit: Susanna Hamilton, Broad Communications From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease. Study after study had suggested that A.

Research 52

Research Immune Response Medical Schools Disease 52

The Pharma Data

JANUARY 27, 2021

Yet insurance does not cover the therapy for stroke patients. That’s partly because after a stroke, the emphasis is often on rehab for any disabilities a patient might have, said Elizabeth Regan, a clinical assistant professor of physical therapy at the University of South Carolina, in Columbia. 27, 2021, online.

Medical Schools 52

Medical Schools Therapies Hospitals Doctors 52

Broad Institute

JUNE 21, 2023

Typically, studying drug therapies is an expensive and time-consuming undertaking. By makenziekohler June 23, 2023 Related Claussnitzer Lab first paragraph The field of microscopy has grown immensely over the last fifty years in its ability to extract both quantitative and qualitative data from microscopic images.

Small Molecule 52

Small Molecule Cell Based Assays Medical Schools Disease 52

NIH Director's Blog: Drug Development

APRIL 2, 2020

This is of particular concern to doctors whose patients are already taking the medications to control hypertension. Since the COVID-19 outbreak, many people have wondered whether taking ACE inhibitors would be helpful or detrimental against coronavirus infection. The team, led by Scott D.

Drug Development 52

Drug Development Drugs Science Medical Schools 52

Broad Institute

MAY 2, 2024

In undergrad, I thought about going to medical school, but I didn’t want to work in a hospital. If you find a novel mutation that you target with a drug in a specific cancer type, you can help people in a really impactful way even though you’re not the doctor treating their disease. You think, “I’ve created something new.”

Science 124

Science Medical Schools Disease Hospitals 124

Broad Institute

DECEMBER 6, 2023

In the future, when doctors give patients cytokine therapies targeting the immune system, they could potentially look in the Immune Dictionary for expected cell-level immune responses. There are many open questions, and having this foundational reference can significantly improve our understanding of the immune system.

Immune Response 138

Immune Response RNA Disease Medical Schools 138

The Pharma Data

DECEMBER 3, 2020

An initial analysis of data from 17/22 patients who completed one of these assessments showed substantially decreased neurocognitive abilities compared to children of the same age level despite the use of multiple anti-epileptic therapies. No investigational medications or other treatments will be provided. Lori Isom, Ph.D.,

Clinical Trials 52

Clinical Trials Protein Expression Pharmacokinetics Trials 52