article thumbnail

Turning science into business: An optimised alternative to antibodies

Drug Discovery World

DS: What motivated you and Dr David Bunka, CTO, to create Aptamer and did you imagine you would one day be operating on such a global scale?    AT : We initially met at the University of Leeds, where David was a post-doctoral researcher studying aptamers, and I was completing my PhD.

Science 130
article thumbnail

The democratisation of cell and gene therapy

Drug Discovery World

DNA purification “Plasmid DNA is an incredibly important part of molecular biology”, says Hummersone. He says: “What we are seeing from a molecular biology perspective is that the genetic material that we want to pack into viral vectors is becoming increasingly complicated. Firstly, AAV is a delicate vector.

Therapies 273
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Battling antibiotic resistance in the lab and the clinic

Broad Institute

He has also emerged in recent years as a skilled and relatable science communicator, renowned for his efforts at Broad and beyond during the COVID-19 pandemic to unpack the fast-moving research on the new virus in an accessible way and give practical advice about masking, vaccines, and other public health measures.

Hospitals 137
article thumbnail

Scaling Phage Therapy

Codon

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 138
article thumbnail

What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Alessa Schaffrath, Doctoral Student, UKE Hamburg, on: ‘Transgenic llama mice – a fast and flexible single domain discovery tool’. Phil Leighton, PhD, Senior Director, Molecular Biology, OmniAb, on: ‘Heavy chain-only transgenic chickens produce human antibodies with robust immune repertoires and high-affinity binding’.

article thumbnail

Breaking the Speed Limit on Cell Division

Codon

During my doctoral training, I split my work between wet lab research and programming, two streams that differed radically in terms of productivity. The researchers chose to discard genes that encode virus-sensing machinery because the cells would be grown in a sterile laboratory environment. The resulting strain of V.

DNA 97
article thumbnail

FAIR Game: making data work harder in the race to market 

Drug Discovery World

Christof Gänzler gained his doctorate in molecular biology from the German Cancer Center (dkfz) in Heidelberg/Germany working on Human Papilloma Virus vaccines. Volume 23 – Issue 4, Fall 2022 . Reference: . About the author .

Marketing 130