Drug Discovery World

NOVEMBER 27, 2023

For instance, the engineering of CHO cells, widely used protein expression system, for various metabolic pathways has resulted in improved expression levels of large molecule drugs and product quality 1,2. After engineering, stable clones are screened, identified, and characterised. Biotechnol Bioeng 2012;118:2326.

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Production Engineering Molecular Biology Drug Development 147

Drug Target Review

MARCH 15, 2024

As discussed above, recent advances in gene editing tools and transposon-based vectors have facilitated targeted and consistent cell line engineering for the development of protein expressing CHO cell lines. Anis also serves on the scientific and editorial advisory board of Genetic Engineering News at Mary Ann Liebert, Inc.

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Engineering Molecular Biology Protein Expression Medical Schools 104

Drug Discovery World

NOVEMBER 9, 2023

These include: Samantha Bailey-Bucktrout, PhD, Senior Vice President, Akamis Bio, on: ‘Tumour specific immunogene therapy to deliver protein therapeutics to solid tumour microenvironments’. Jonathan Fisher, PhD, Group Leader, University College London, on: ‘Local secretion of immune active proteins for direct and bystander tumour killing’.

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Engineering Protein Production Therapies Science 130

Drug Discovery World

NOVEMBER 13, 2023

Yuchih Lin, Doctor, Sino Biological Europe, on: ‘Accelerating drug discovery using advanced antibody development platforms’. Sandeep Talapatra, PhD, Leader Protein Science, Protein Cell & Structural Sciences, GSK, on: ‘Enhancing success rates and throughput of protein purification for drug discovery: A medium-scale approach’.

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Engineering Science Bioinformatics Vaccine 147

The Pharma Data

DECEMBER 3, 2020

protein expression by leveraging the non-mutant (wild-type) copy of the SCN1A gene to restore physiological Na V 1.1 Participants continue to receive their usual care, and will be observed by a team of doctors and nurses over time for up to two years. .–( BUSINESS WIRE )– Stoke Therapeutics , Inc.

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Protein Expression Clinical Trials Pharmacokinetics Trials 52