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Molecular mechanisms of corona drug candidate Molnupiravir unraveled

The Pharma Data

The antiviral agent incorporates RNA-like building blocks into the RNA genome of the virus. If this genetic material is further replicated, defective RNA copies are produced and the pathogen can no longer spread. ” Mutations in the genome stop the virus.

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California, Iowa Toughen Restrictions as COVID Cases Climb

The Pharma Data

After getting the virus under control, California Gov. Until now, Reynolds had ignored infectious disease experts who say masks are one of the most effective tools to control the spread of the virus, the Post reported. Moderna’s COVID Vaccine Shows 94.5% effectiveness. In some good news, Moderna Inc. percent effective.

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FDA Approves First Rapid COVID Test for Home Use

The Pharma Data

Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus. ” COVID Vaccines Move Closer to Emergency Use Approval. announced earlier this week that early results show its coronavirus vaccine is 94.5

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Happy New Year … and a Look Back at a Memorable 2015

NIH Director's Blog: Drug Development

This gene-editing system consists of a short segment of RNA that is attached to an enzyme. The RNA is preprogrammed to find a distinct short sequence of DNA and deliver the enzyme, which acts like a scalpel to slice the sequence out of the genome. It’s fast and pretty precise. NIAID scientists, led by Drs. Protein Cell.

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Battling antibiotic resistance in the lab and the clinic

Broad Institute

He has also emerged in recent years as a skilled and relatable science communicator, renowned for his efforts at Broad and beyond during the COVID-19 pandemic to unpack the fast-moving research on the new virus in an accessible way and give practical advice about masking, vaccines, and other public health measures.

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Defense-Forward Biosecurity

Codon

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. While reading all the sequences present in a sample, researchers want to find any that are out of place, such as those that belong to a never-before-seen virus.

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New “dictionary” of immune responses reveals far more complexity in the immune system than previously thought

Broad Institute

Using single-cell RNA sequencing to analyze gene expression in individual cells, the researchers have found how 86 major cytokines affect 17 immune cell types in mice. I hope our approach helps scientists make sense of any immune process, vaccine, disease, or therapy response, so that one can infer which cytokines are contributing to it.