Drug Target Review
JULY 6, 2023
1 TPD is expected to challenge undruggable proteins, which are highly difficult to target by conventional small molecules. 1 The concept of TPD was first demonstrated with a heterobifunctional small molecule to degrader a protein of interest in the early 2000s. References: Békés M, Langley DR, Crews CM.
The Pharma Data
NOVEMBER 22, 2020
SAN DIEGO–( BUSINESS WIRE )– Vividion Therapeutics , a biotechnology company discovering and developing selective small molecule medicines that drug traditionally inaccessible targets, today announced that Jeffrey Hatfield has been appointed as the company’s chief executive officer. 23, 2020 13:30 UTC. About Vividion.
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Drug Target Review
MARCH 28, 2024
Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. She came to Bruker in 2021 from a faculty position in the Department of Chemistry at San Diego State University following a post-doctoral fellowship at The Scripps Research Institute in Gary Siuzdak’s group.
Elrig
APRIL 30, 2024
One aim of this work was to develop a set of tools to be later used in a high-throughput screen to identify small molecules for potential therapeutic uses as the current large molecule therapeutics do not show good selectivity. I had my first post-doctoral stay in the lab of Prof. In August 2017, I joined Prof.
Broad Institute
JUNE 21, 2023
The researchers also looked at the tool’s ability to detect changes in cell morphology after exposure to drugs and small molecule compounds. LipocyteProfiler also highlighted discrete cellular mechanisms and pathways when used to analyze metabolic traits associated with high polygenic risk scores.
KIF1A
MAY 27, 2023
After speaking at our 2019 conference and receiving her doctorate, Dr. Lessard joined KIF1A.ORG as its first staff scientist, bringing with her a wealth of expertise in KIF1A, both her own and that of her research colleagues. Lessard became part of the KIF1A.ORG community through her graduate research on the biomechanical properties of KIF1A.
KIF1A
JUNE 30, 2023
As families, scientists, doctors and our friends around the world navigated the challenges of 2022, the KIF1A.ORG community worked together to reach new heights. KAND Clinician Directory : Trying to find a doctor? This short, 4-minute video helps families, doctors, teachers, friends and others understand KAND in plain language.
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