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Phase II trial investigates allogeneic CAR-T for large B-cell lymphoma

Drug Discovery World

Allogene Therapeutics and Foresight Diagnostics have announced the initiation of a Phase II trial evaluating the use of cemacabtagene ansegedleucel (cema-cel) as part of the first line treatment regimen for newly diagnosed large B-cell lymphoma (LBCL) patients who are likely to relapse.

Trials 147
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UK approval for CBD pain treatment

Drug Discovery World

The UK Medicines and Healthcare Products Regulatory Agency (MHRA) has approved a CBD/THC combination treatment under its Named Patient programme and other compassionate areas. NanaDol will be available to patients in the UK through doctor prescription only for pain (including cancer-related bone pain).

Treatment 246
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After surprise trial failure, ALS doctors brace for one less treatment option

BioPharma Drive: Drug Pricing

Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.

Doctors 124
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Patient Perspective: Jamie Troil Goldfarb shares her clinical trial experience [video]

Antidote

For individuals living with a condition like melanoma, volunteering to participate in a clinical trial can be a rewarding experience. Individuals with Jamie’s specific diagnosis are given a 14% 5-year survival rate — but through participating in an immunotherapy clinical trial, Jamie is living without evidence of the disease.

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Medicinal cannabis: Why more clinical trials and better access is needed

Drug Discovery World

Big pharma is helping to shape the focus The good news is that clinical trials are on the increase and market education is upping pace. Meanwhile, the Pfizer purchase of Arena Pharmaceuticals, highlights cannabinoid-based bowel disease treatments as a promising area.

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A combined PET-MRI scan could improve treatment for patients with early breast cancer

SCIENMAG: Medicine & Health

Milan, Italy: Using a combined scanning technique on patients with early-stage breast cancer improved treatment in almost three out of ten cases in a trial presented at the 14th European Breast Cancer Conference today (Thursday). [1]

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Researcher’s Perspectives: How a personal connection created a career in clinical trials

Antidote

Behind every new treatment is the incredible team of doctors, researchers, patients, and clinical trial specialists who worked on the research that made it possible.