Drug Development Engineering Immune Response 
DrugBank
FEBRUARY 12, 2025
The pharmaceutical industry grapples with the persistent challenge of high attrition rates and escalating costs inherent in drug development. This necessitates exploring alternative strategies to expedite drug discovery and optimize resource allocation.
Drug Target Review
DECEMBER 5, 2024
2,3 Engineering both the capsid and DNA cargo improves the safety and efficacy of rAAV vectors and expands their clinical applications. Therefore, vectors based on these serotypes may enable targeted gene delivery and optimal transduction efficiency.
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The Pharma Data
JANUARY 4, 2021
Chimeric PD-1 T-cells also release cytokines to further initiate immune responses to eradicate the tumor cells. The pipeline development is leveraged through the Company’s proprietary target discovery engine called “DIAMOND.” The Company maintains offices in Houston, Texas.
Agency IQ
APRIL 12, 2024
In drug development, biochemical assays might be used to determine a product’s binding affinity to a target receptor of interest, along with the strength, stability and duration of the target-ligand complex after the product binds to the receptor. The new draft guidance can be broken into three main parts.
Broad Institute
OCTOBER 11, 2023
The drugs work by blocking a protein, PD-1 — which helps keep immune responses in check — and stimulating the immune system to attack tumors. We wanted to see whether there were as yet undiscovered drug targets that would lead to amazing cancer immunotherapies,” Manguso said.
Drug Target Review
JANUARY 15, 2024
To be therapeutically useful, antigenic peptides must be presented in a way that allows immune responses to destroy cancer cells without causing unacceptable damage to healthy tissue. With convergent technology, it is possible to engineer monoclonal antibodies that mimic the specificity of TCRs for tumour‑specific pHLA targets.
Codon
FEBRUARY 13, 2024
Such contaminants could have the same toxic effects as the bacterial infection, or provoke a severe immune response in the patient, and therefore the phage mixtures must go through extensive purification and testing procedures. Locus has products in development targeting four common sources of bacterial infections: E.
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