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Together, the tools estimate how a drug may impact diverse outcomes of interest to drugdevelopers: general cellular health, pharmacokinetics, and heart and liver function. Drugdevelopers also assess pharmacokinetic effects, or how an organism absorbs, distributes, metabolizes, and clears a drug.
This is reflected in scientific discoveries across many research disciplines including immunology , molecularbiology , medicine, and diagnostics. Specific areas where they have had a wide impact include virology , bacteriology, biotechnology , fungal biology, cancer and oncology (e.g.
In 2024 alone, almost 50 antibody drug candidates are anticipated to enter regulatory review, the majority of which are mAbs. Aside from the advent of complex antibody-based drugs, the industry is facing some additional changes which are shaping drugdevelopment. Methods in MolecularBiology. 2021;291–306.
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