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Women in Stem with Dr Beate Mueller-Tiemann

Drug Target Review

I always found science fascinating, but I really fell in love with it in high school when I was introduced to biochemistry and molecular biology. It was then that I knew I wanted to dedicate my career to science. Biochemistry and molecular biology fascinated me in school. BECOME A ROLE MODEL!

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Optimizing your ELISA Assays | BMG LABTECH

BMG Labtech

Enzyme-Linked Immunosorbent Assays (ELISAs) are an essential technique in today’s laboratory with many applications in the life sciences. They are often the method of choice to detect or measure specific biological molecules (analytes) for diagnostics, drug discovery or fundamental research.

Vaccine 98
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How organoids can redefine pre-clinical research

Drug Target Review

5 Organoids are recognised as New Alternative Methods (NAMs) in drug development. This recognition was codified by the United States Food and Drug Administration (FDA) in 2022 with the signing of the FDA Modernisation Act 2.0 This can aid in the development of safer, more effective therapeutic strategies.

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Medicinal Chemistry In The Age Of Artificial Intelligence

LifeSciVC

We are constantly reminded how we are in the midst of an artificial intelligence revolution of the drug development process which promises to completely transform how we develop drugs with increases in productivity of an order of magnitude or more. One final parallel to 2001.

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De-risking drug discovery with predictive AI

Broad Institute

Together, the tools estimate how a drug may impact diverse outcomes of interest to drug developers: general cellular health, pharmacokinetics, and heart and liver function. Drug developers also assess pharmacokinetic effects, or how an organism absorbs, distributes, metabolizes, and clears a drug.

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Driving efficiency across upstream bioprocess workflow

Drug Target Review

Transposon technologies are gaining traction due to their accuracy in integrating the gene of interest into the host genome, making them an important tool for accelerating large molecule drug development. Anis works within the strategy group in Life Sciences at Revvity, Inc. Disclaimer: For research use only.

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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

This method was more about serendipity than science. But as molecular biology has advanced, so too has our approach to finding new drugs. Its structure makes it incredibly difficult for drugs to bind effectively, which has stymied drug development for decades.