Drug Target Review

JULY 4, 2023

Antibody drug conjugated with cytotoxic payload. antibody linked to a biologically active cytotoxic (anticancer) payload or drug 3d rendering. With the ultimate long-term goal of optimum dosing being determined before Phase 3 registration trials and before a drug is marketed. Cancer Cell [Internet].

Small Molecule 145

Small Molecule Drugs Clinical Pharmacology Trials 145

Drug Target Review

MARCH 15, 2024

About the author Dr Petra Dieterich, Senior Vice President at Abzena Petra has 30 years experience of in drug development in the pharmaceutical industry with a focus on supporting CMC activities. She has held leadership positions in Project Management, Technical Operations, and Business Development.

Organic Chemistry 59

Organic Chemistry Pharma Companies Clinical Trials Pharmaceuticals 59

Drug Target Review

MAY 1, 2024

Jamie Rich, PhD is Senior Director of Technology, ADC Therapeutic Development at Zymeworks Inc. He has more than 17 years of experience in ADC and protein chemistry research and drug development. Dr Rich received a PhD in organic chemistry from the University of Alberta.

Drugs 69

Drugs FDA Approval Organic Chemistry Small Molecule 69

NIH Director's Blog: Drug Development

OCTOBER 30, 2018

Now comes word of another absolutely incredible use of cryo-EM: determining with great ease and exquisite precision the structure of the smaller organic chemical compounds, or “small molecules,” that play such key roles in biological exploration and drug development.

Small Molecule 52

Small Molecule Science Drug Development Organic Chemistry 52

Elrig

APRIL 29, 2024

After graduating, Miles went on to work as a scientist on AstraZeneca’s Research and Development graduate programme, working on projects in biocatalysis, computational organic chemistry and machine learning for drug discovery.

Bioinformatics 59

Bioinformatics Drugs Molecular Biology Cell Based Assays 59

Drug Target Review

MARCH 8, 2025

After earning my undergraduate degree from Connecticut College, followed by a PhD in organic chemistry from the University of Michigan, I landed a position as a researcher at a large biopharmaceutical company. The future of CMC lies in embracing more agile, science-driven approaches to drug development and manufacturing.

Science 52

Science Organic Chemistry Process Chemistry Therapies 52