Drug Discovery World

NOVEMBER 29, 2023

Researchers have created a mathematical model that can accurately depict Alzheimer’s disease progression in individual patients, paving the way for personalised treatment and faster development of therapies. The researchers expect their model will be ready for use in a clinical setting within five years.

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Drug Discovery World

APRIL 20, 2023

Dr Paula Moran, Dr Kiri Granger, Dr J Mark Treherne , and Dr Jenny Barnett explore the effects of long Covid-19 symptoms and what the opportunities are for drug developers working to treat post-Covid-19 cognitive impairment. These may provide an opportunity for treatment for post-Covid-19 cognitive impairment.

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Drug Discovery World

JUNE 5, 2024

The new partnership, which will involve scientists from both organisations working closely together, is part of LifeArc’s MND Translational Challenge, aimed at discovering innovative and potentially disease-modifying treatments for MND, a key component of the new UK MND Research Institute.

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Drug Discovery World

JUNE 14, 2024

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. Charlotte Allerton, Head of Discovery and Early Development, Pfizer, said: “With obesity expected to impact 1.9

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Drug Discovery World

MARCH 10, 2023

Cancer Research UK and UCB have agreed a clinical development collaboration to advance two of UCB’s investigational oncology antibody candidates through clinical trials. If successful in clinical trials the investigational candidates may have the potential to offer cancer patients access to new targeted treatment options.

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DrugBank

AUGUST 15, 2024

Drug development is challenging, including not only the complexities of biomolecular drug mechanisms but also the convolutions of regulatory pathways and commercialization strategies. This includes funding large-scale clinical trials and establishing robust manufacturing/distribution networks.

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Drug Discovery World

AUGUST 25, 2023

DDW’s Megan Thomas looks at a day in the life of Giusy Di Conza , Head of Research at iOnctura. GDC : I’m Head of Research for a young, dynamic biotech called iOnctura. We are pioneering research into new biological mechanisms for established drug targets. It’s a really exciting time for oncology drug development.

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BioPharma Drive: Drug Pricing

DECEMBER 20, 2023

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

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Drug Discovery World

OCTOBER 10, 2023

The National Institutes of Health has awarded the first phase of a roughly $40m grant to Yale University to advance a novel CRISPR-based gene-editing delivery platform for the targeted treatment of neurogenetic diseases. The post NIH awards ‘bench-to-bedside’ grant for CRISPR drug development appeared first on Drug Discovery World (DDW).

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Drug Discovery World

OCTOBER 31, 2023

Professor Andy Whiting and Dr Tony Lockett discuss how specific levels of a protein could be used to advance drug development in neurodegenerative diseases. However, the treatment was successful in reducing the SOD1 associated gene product and NfL.

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Drug Discovery World

APRIL 29, 2024

Dr Currien MacDonald, Medical Chair Director at WCG, discusses the challenges and opportunities presented by cannabis research. Research support Support for researching cannabidiol is expanding. More importantly, cannabis research received additional governmental support for continued investigation at the end of 2022 with H.R.8454,

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Drug Discovery World

SEPTEMBER 1, 2022

These sequence-defined, recombinant antibodies are suitable for developing highly selective and sensitive pharmacokinetic (PK) and anti-drug antibody (ADA) assays for evolocumab and its biosimilars. Evolocumab is a monoclonal antibody used for the treatment of hyperlipidemia, or elevated levels of cholesterol and other lipoproteins.

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Drug Discovery World

OCTOBER 9, 2023

Despite the size of the market and the global impact, there are currently no effective treatments. DS: As new variants begin circulating, what impact could this finding have on our understanding and the potential treatment of long Covid? DS: Why do you think we are no closer to treatments for long Covid?

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Drug Discovery World

MAY 9, 2023

Jantzen Sperry , PhD, Director of Scientific Operations at Certis Oncology looks at how the adoption of orthotopic PDX models can elevate the impact of cancer research and improve translation in oncology drug development. Fewer than 5% of oncology drugs that enter clinical trials in the US receive US FDA approval.

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Drug Discovery World

MAY 13, 2024

The University of Texas MD Anderson Cancer Center has been awarded $20 million to strengthen neurodegeneration research. The BNDC is a core component of MD Anderson’s Therapeutics Discovery division, which unites scientists, clinicians and drug development experts to eliminate the bottlenecks stifling traditional drug discovery.

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Drug Discovery World

DECEMBER 28, 2023

Paediatric oncologist Gauri Sunkersett shares her unique background and research approach at AbbVie to help find answers for the youngest blood cancer patients. When I was a second-year resident training as a paediatric oncologist at Nicklaus Children’s Hospital, I met a teenage boy diagnosed with Hodgkin’s Lymphoma.

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Drug Discovery World

MARCH 2, 2023

This has left many living with rare diseases without available or approved treatments and support for their conditions. AI is revolutionising clinical trials and drug developments just as it is transforming other sectors, but in order for AI to make progress in rare diseases, the UK needs further investment to increase uptake and use.

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Drug Discovery World

JULY 5, 2023

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. RA: What is the current state of the cancer research industry? Mark Garner, PhD., MG: I am responsible for Agilent’s cancer segment.

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Drug Discovery World

JULY 25, 2023

Justin Hay , Senior Director, Amy Cheung Senior Director of Integrated Drug Development, and Patrick Loebs Director, at Certara, examine recent changes in paediatric guidelines and how they affect drug development projects. The guidance mentions PBPK four times regarding renal function and DDIs.

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Drug Discovery World

DECEMBER 5, 2022

AI-driven genomics company Genomenon will partner with COMBINEDBrain, SynGAP Research Fund, and SLC-6A1 Connect and their pharma partners to deliver genomic data on their diseases of focus. . Mike Graglia founded the SynGAP Research Fund when his son was diagnosed with SYNGAP1 in 2018.

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Drug Discovery World

OCTOBER 27, 2023

Organ-chips combine cell culture with microfluidics to emulate the biological forces of different organ tissues and/or disease states, allowing pharmaceutical researchers to determine a drug candidates’ efficacy and toxicity ahead of clinical trials. Could organ-chips replace other research methods? Not yet, according to Ewart.

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Drug Discovery World

JULY 15, 2024

From 5-10 April 2024 in San Diego, the cancer research community gathered for the annual meeting of the American Association for Cancer Research (AACR). DDW’s Megan Thomas spoke with biotech and pharma leaders to understand more about the cancer research landscape.

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PPD

SEPTEMBER 25, 2023

As the clinical trial landscape evolves, drug developers are faced with novel challenges and changes in study recruitment, trial size and structure, and more. The adoption of new innovations, strategies and technologies offers opportunities to address persistent challenges and develop suitable approaches for the future.

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Drug Discovery World

NOVEMBER 23, 2022

The CoE aims to develop best practices and guidelines to use social media analysis as RWD for patient-focused drug development. While there is a concise regulatory framework on many sources of RWE for drug approval and Health Technology Assessments (HTA), this guidance is lacking for social media. .

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Drug Discovery World

JUNE 29, 2023

Cancer Research UK has joined the PRIME-ROSE project, a Europe-wide effort to boost patient access to precision cancer medicine (PCM). Approved by the European Commission, PRIME-ROSE aims to bring together a network of similar clinical trials which are being implemented to broaden patient access to a wider range of innovative PCM treatments.

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Drug Discovery World

JANUARY 24, 2023

There are currently no cures for either disease, but researchers hope that these results will significantly speed up the search for new treatments. Tracking the progression of FA and DMD is normally done through intensive testing in a clinical setting. Image shows: Luchen Li, wearing the sensor suit, and Professor Aldo Faisal.

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Drug Discovery World

NOVEMBER 29, 2023

DDW’s Megan Thomas speaks to Jennifer Cann, Director of Pathology at Virscio, a company solving human health challenges through biomedical research. MT: Can you provide a top line summary of your research? The post Meet the Researcher: Jennifer Cann, Director of Pathology, Virscio appeared first on Drug Discovery World (DDW).

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Drug Discovery World

MARCH 16, 2023

2 EP0042’s ongoing clinical-stage study follows earlier drug discovery and development work led by The Institute of Cancer Research, London, which was funded by organisations including The Institute of Cancer Research, Breast Cancer Now and Cancer Research UK. and Leung, A. and Wang, H-G.

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Drug Discovery World

JANUARY 30, 2023

As research progresses it is hoped that cell and gene therapies will offer innovation for the future. The event will cover aspects affecting growth of the CGT market, including how manufacturing technologies are enabling drug development, what these therapies mean for the healthcare market, and the opportunities for developers.

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Drug Discovery World

FEBRUARY 9, 2023

Launched in 2020, the Oxford-based business hopes the designation will “open regulatory discussions, supplement funding, increase the viability of drug development and enable quick access to market a treatment.” SynaptixBio CEO and co-founder Dr Dan Williams said the designation was a “monumental step forward” in its bid to treat the disease.

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Alta Sciences

AUGUST 29, 2024

Engaging at the outset with a fully integrated and experienced drug development partner can ensure safety, with timely data sharing at every step of the drug development plan, and facilitate agile, flexible decision-making and planning. billion USD in 2023 to $166.53 billion USD by 2028. WHAT IS THE ALTASCIENTIST ?

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Drug Discovery World

JUNE 2, 2023

Health data generated by hospitals, healthcare providers, research organisations and clinical trials hold the potential to advance research and innovation, improve patient care and accelerate drug development. Lifebit’s Trusted Research Environment technology provides real-world data on cancer patients.

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PPD

JULY 29, 2024

In today’s data-driven world, AI has become valuable and indispensable, enabling organizations to extract valuable insights from vast amounts of data, make informed decisions and drive innovation across different sectors — including drug development.

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Drug Discovery World

FEBRUARY 16, 2024

DDW recently hosted an online event, sponsored by Taconic Biosciences, which outlined areas of advancement and opportunity in the cancer research market. New drug discovery and development concepts The event started with a panel discussion on new drug discovery and development concepts and tools in cancer research.

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Drug Target Review

AUGUST 7, 2024

The pharmaceutical industry is undergoing a major shift towards the development of breakthrough medicines and advanced therapies. This continued innovation highlights the complexity of the drug development process, particularly as the field is highly regulated by health authorities around the world.

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Drug Discovery World

JANUARY 17, 2023

Genoscience Pharma, a clinical-stage biotech company developing lysosomotropic drug candidates for the treatment of cancer, fibrosis and auto-immune diseases through autophagy modulation has launched the ABE-LIVER study, along with trial sponsor Grenoble University Hospital. . The trial . The primary criteria is PFS.

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Drug Discovery World

DECEMBER 5, 2023

Cancer Research UK (CRUK), Cancer Research Horizons, and precision oncology company Guardant Health have launched a collaboration to advance cancer treatment. This includes the DETERMINE trial – the first UK national precision medicine trial in rare cancers, and other CRUK and Cancer Research Horizons research collaborations.

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