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HIGH SCHOOL SCIENTISTS AND ENGINEERS WIN NEARLY $9 MILLION AT THE REGENERON INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2023 Regeneron Pharmaceuticals, Inc. I am humbled by the creativity and determination demonstrated by these exceptional students and proud of all they have accomplished with their outstanding research abilities.
Genome engineering and gene therapies that manipulate DNA sequences in cells have driven a biotechnological revolution over the past decade. The limitations of natural AAV serotypes in meeting all clinical needs has spurred growing interest in AI-driven AAV engineering approaches. Nature reviews Drug discovery 18 , 358-378 (2019).
Sygnature Discovery is delighted to announce that its customer, River BioMedics , has raised an additional €2M in seed funding to continue its life-saving cardiovascular drugresearch. The biotech’s aim is to develop medicines that treat the underlying cause of heart failure rather than merely treating the symptoms.
As the powerful discovery engine of the company, Innovent Academy is committed to focusing on the first-in-class innovation with unmet medical need. In addition, in order to achieve next level strategic goal of developing global first-in-class product in 5-10 years, Innovent Academy has been established.
CMap utilizes gene expression profiles to connect drugs, genes, and diseases, enabling researchers to identify potential repurposing candidates based on their transcriptional signatures. DrugBank data is not only valuable for manual exploration but also serves as a powerful engine for computational drug repurposing.
While fundamental research is often productive in mice, translational drugresearch tends to be relatively intolerant to biological differences. This allowed researchers to easily engineer mice by editing the stem cells, and then injecting the edited cells into a mouse embryo.
New era in drugresearch: data access and NGS The 1990s and 2000s marked a turning point in the drug development landscape, facilitated by a combination of cultural and technological factors that enabled regulatory changes, technological innovations and methodological advances.
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