BioPharma Drive: Drug Pricing

MARCH 12, 2024

Allogene’s partnership with Arbor is designed to help the company stand out in what’s quickly become one of the industry’s hottest areas of drug research.

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Drug Discovery World

JULY 26, 2024

‘Encouraging’ results for potential disease-modifying ALS drug New clinical data have shown that TikoMed’s low molecular weight dextran sulfate compound ILB is safe and well tolerated in patients with amyotrophic lateral sclerosis (ALS). Fox Foundation for Parkinson’s Research (MJFF).

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Drug Discovery World

MAY 28, 2024

The growth will in part by driven by an increase in the use of imaging modalities in drug research and development. Download this exclusive eBook to learn more about: How new imaging modalities are supporting the development of new therapies for cancer and neurodegenerative diseases. billion in 2023 and is poised to reach $15.58

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DrugBank

AUGUST 20, 2024

You’ll discover real-world examples, such as the transformation of KRAS from an undruggable target to a success story in targeted therapy. The Power of Drug Repurposing Explore the immense potential of drug repurposing as a strategy for targeting undruggable targets.

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Drug Target Review

OCTOBER 26, 2023

Genome engineering and gene therapies that manipulate DNA sequences in cells have driven a biotechnological revolution over the past decade. Consequently, an increasing number of academic researchers and companies are entering this field. Molecular Therapy 20 , 1831-1832 (2012). Nature 578 , 229-236 (2020). Ylä-Herttuala S.

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Drug Discovery World

AUGUST 28, 2023

And we’ve shown that, at least in animal models of these diseases, our drug molecules work really well. DS: Your research has so far focused on Parkinson’s disease and Amyotrophic Lateral Sclerosis (ALS). What is the potential for this type of therapy in treating other neurodegenerative disorders?

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Drug Discovery World

MARCH 22, 2023

It will combine the use of novel Huntington’s disease drug targets from Aitia’s Gemini Digital Twins with UCB’s expertise in drug research and preclinical model systems in neurodegeneration, with the aim to accelerate the discovery of new therapies for people living with Huntington’s disease.

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Drug Discovery World

JUNE 14, 2023

Nearly three-fourths of life sciences organisations surveyed have invested in digital pathology to advance drug research and development (R&D), according to new research commissioned by Proscia. To read all of the findings, access the full report here.

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Drug Discovery World

MARCH 13, 2023

The cell and gene therapy (CGT) landscape has grown significantly in the past year. Between the 24 therapies already approved by the FDA 1 and a marked increase in clinical trials, widespread accessibility to precision medicine feels within reach. One example: Zynteglo, a newly approved gene therapy priced at a record-breaking $2.8M

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Vial

MAY 20, 2024

In this article, we will define preclinical and clinical CROs, as well as highlight the unique needs and challenges of these organizations in their respective stages of drug research. What is a Pre-Clinical CRO? The global preclinical CRO market was estimated to be valued at US$5.7 billion in 2022 and is projected to reach US$10.2

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Crown Bioscience

AUGUST 2, 2021

Interest in IMIDs has grown rapidly in recent years, largely fueled by the view that IMIDs share common inflammatory pathways, and therefore, there is the possibility that novel therapies that work in one IMID may work in other IMIDs.

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DrugBank

MAY 15, 2024

The binding pockets on KRAS are shallow and polar , not ideal for the kinds of interactions needed for strong, effective drug binding. In fact, it's one of the most exciting areas in drug research today. One approach is to look beyond the traditional drug molecule.

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Advarra

AUGUST 16, 2022

The law established the Office of Orphan Products Development , providing financial incentives for pharmaceutical companies to develop orphan drugs and making it more viable to invest in orphan drug research and development. The impact was clear: Between 1983 and 2020, FDA approved 599 orphan drugs. A Lasting Impact.

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NIH Director's Blog: Drug Development

FEBRUARY 16, 2021

This improvement stems from several factors, including the FDA’s emergency use authorization (EUA) of a number of therapies found to be safe and effective for COVID-19. ACTIV was founded last April to accelerate drug research that typically requires more than a decade of clinical ups and downs to develop a safe, effective therapy.

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Drug Discovery World

NOVEMBER 16, 2022

Current research . With 3D biology offering potentially more benefits to drug researchers compared to 2D biology, the question arises just what areas of disease are currently being driven by the likes of organoids. “We’ve identified four 3D organoid models that we feel encompass 80% of what everyone is doing.

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Drug Discovery World

JULY 22, 2022

But while psychedelic drug research has witnessed a relative roller-coaster ride of effort since the mid-20th century, more recent interest in the use of psychedelics for treating mental health and psychiatric disorders has spurred a raft of clinical trials 1.

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Drug Discovery World

FEBRUARY 9, 2023

The first is that in-roads made in decoding the complexity of human disease will make drug discovery more difficult and costly, limiting the potential to develop new life-saving therapies. I believe this is where the future of drug research and development hinges.

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Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

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Drug Discovery World

AUGUST 8, 2023

Outside of academia, there are institutions such as the CSIR- Central Drug Research Institute (CDRI), a multidisciplinary research laboratory in Lucknow 11. The growth and potential in Genome Valley are expressed in the continuous investment in the hub. million) at the city’s life sciences hub 14.

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The Pharma Data

JANUARY 26, 2021

percent) in patients taking therapy and 36 events (7.0 Bamlanivimab and etesevimab together also demonstrated statistically significant improvements on all key secondary endpoints, providing strong evidence that the therapy reduced viral load and accelerated symptom resolution. who require oxygen therapy due to COVID-19, OR.

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Codon

JANUARY 21, 2024

You can do a challenge trial with deadly diseases, but you need a “rescue therapy.” There have been deaths in phase 1 medical and drug research among healthy participants. We wouldn't do a challenge trial for Ebola, because the disease is extremely severe, and there are currently no licensed treatments or vaccines.

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The Pharma Data

APRIL 24, 2021

In 1999, Novartis launched the first fixed-dose Artemisinin-based Combination Therapy (ACT) and in 2009, the first dispersible pediatric ACT developed in partnership with Medicines for Malaria Venture (MMV). Follow us on social media at #MalariaFuture. The EDCTP grant of EUR 21.9

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Agency IQ

JUNE 9, 2023

The problems: Although the current regulation stimulated orphan drug research, it didn’t do enough The regulation fostered development of medicines for rare diseases since implementation, but not enough. High-priced cell and gene therapies are being increasingly developed for rare diseases.

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Drug Discovery World

OCTOBER 17, 2022

The ability to do this is essential at each of the three steps in the drug discovery process – create, test, and choose. Harnessing the full potential of data produced in a drug research lab depends on many factors, including the way research is done.

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Drug Discovery World

JULY 3, 2024

The AI revolution Artificial intelligence (AI) is becoming an integral tool in drug discovery, and Swiss researchers have been some of the first to capitalise on and progress this new resource. Swiss companies are also applying AI beyond preclinical drug discovery, to clinical trials and upskilling staff.

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Codon

JUNE 2, 2024

Without mouse models, we may never have developed polio and meningitis vaccines, organ transplants, GLP-1 drugs, gene therapies , or any other number of transformative treatments. Today, somewhere on the order of 30 million rodents are used yearly in biomedical research in the U.S.

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