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Advanced 3D cell-based technologies

Drug Target Review

1,2 This miniature organ chip devices emulate 3D structures with tissue-specific cell types and recreating organ functional units in an in vitro setting to test the effects of drugs and detailed reviewed. Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity.

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An Evolving Regulatory Environment for Rare and Orphan Diseases

Advarra

The Orphan Drug Act of 1983 was instrumental in changing the number of orphan drugs approved in the U.S. The law established the Office of Orphan Products Development , providing financial incentives for pharmaceutical companies to develop orphan drugs and making it more viable to invest in orphan drug research and development.

Disease 52
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Women in Stem with Andrea Pfeifer

Drug Target Review

We are the only company in the world including this population in any Alzheimer’s drug trial, and we are very proud of this! People from different backgrounds bring different experiences and points of view, and it is this diversity of knowledge and opinion that can often make the difference in pharmaceutical development.

Disease 95
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Deliberate Dysentery

Codon

People are hesitant to do this because it's not a particularly flashy disease to research, nor is this population the focus of major pharmaceutical companies. There have been deaths in phase 1 medical and drug research among healthy participants. AP: Who would you encourage to participate in human challenge trials?

Vaccine 128