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Lessons from Monte Carlo Models: Why Drug Development is Hard

DrugBaron

But not everyone in drug development is playing this game. No wonder investing in drug development is so hard! The single most important skill for investing in drug development, or managing a portfolio of assets in a company, is recognizing when the “switch point” comes for each asset. And that is easier said than done.

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Insurers Should Start Paying For Life-Changing Weight Loss Drugs

Forbes: Drug Truths

Ultimately, these drugs will also lower the nation’s healthcare bill. They should be made available to all who need them. Insurance companies need to make this happen as soon as possible.

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Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry

Drug Hunter

Macrocyclic molecules, containing 12 or more atoms in a ring system, are increasingly prevalent in drug discovery, with over 67 macrocyclic drugs approved so far and several notable examples of clinical success highlighted on Drug Hunter recently, including MK-0616 , repotrectinib , and pacritinib.

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Early Impact Of The Inflation Reduction Act On Drug Discovery

Forbes: Drug Truths

There is another aspect of this provision of the IRA that is starting to be felt – "the small molecule penalty"

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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New drug triggers rapid cell death in cancer models

Broad Institute

New drug triggers rapid cell death in cancer models By Karen Zusi-Tran October 29, 2024 Breadcrumb Home New drug triggers rapid cell death in cancer models BRD-810 inhibits the MCL1 protein and reactivates apoptosis in tumor cells, displaying therapeutic potential in animal models. The result was the compound named BRD-810.

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AI Uses Zero-Shot Learning to Find Existing Drugs for Treating Rare Diseases

Nvidia Developer: Drug Discovery

A groundbreaking drug-repurposing AI model could bring new hope to doctors and patients trying to treat diseases with limited or no existing treatment options. A groundbreaking drug-repurposing AI model could bring new hope to doctors and patients trying to treat diseases with limited or no existing treatment options.

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