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SARS-CoV-2 Protease Inhibitors: An Attractive Approach for Treating COVID-19

PerkinElmer

JUNE 3, 2022

Inhibiting SARS-CoV-2 Proteases Currently, limited therapeutic options are available to those who are infected with SARS-CoV-2 and attempts to repurpose approved drugs have shown minimal success so far. The second virtual screen focused on optimization of a hit from a previous crystallographic fragment screen.

Fragment Screening 52
Fragment Screening Clinical Trials Vaccine Pharmacokinetics 52
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SARS-CoV-2 main protease. Crowdsourcing, peptidomimetics and fragments

Molecular Design

JULY 18, 2020

Satchel Paige (1906-1982) The COVID Moonshot and OSC19 are examples of what are sometimes called crowdsourced or open source approaches to drug discovery. Open source drug discovery originated with OSDD in India and it should be noted that the approach has also been pioneered for malaria by OSM.

Biochemical Assays 52
Biochemical Assays Fragment Screening Pharmacokinetics Drugs 52
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