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Finding small molecule drugs is much harder than finding a needle in a haystack – discovering the right arrangement of atoms to bind precisely to a protein target to elicit a particular response is a problem of vast dimensionality. We already talked about choosing carefully a more limited set of compounds to make.
The project has helped the United States Pharmacopeia (USP) deal with the challenges caused by drug product recalls due to unsafe levels of nitrosamine impurities. After working for pharmacompanies for nearly 20 years, I decided to work with USP so that I could utilise my skills in the development of standards.
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