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Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry

Drug Hunter

Macrocyclic molecules, containing 12 or more atoms in a ring system, are increasingly prevalent in drug discovery, with over 67 macrocyclic drugs approved so far and several notable examples of clinical success highlighted on Drug Hunter recently, including MK-0616 , repotrectinib , and pacritinib.

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Process Chemistry Unleashed: A 'Fit-for-Purpose' Approach to Accelerate IND Filing

Fierce BioTech

Process Chemistry Unleashed: A 'Fit-for-Purpose' Approach to Accelerate IND Filing pesurya Thu, 07/27/2023 - 11:27 Tue, 09/05/2023 - 10:00 Resource Type Webinar Qixuan Lu Duration 60 Minutes Process chemistry plays a pivotal role in various stages of the pharmaceutical R&D cycle. Click here to login.

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Form and Formulation

Sygnature Discovery

Here at Sygnature Discovery, we offer specialised expertise in early-stage drug formulation. These strategies are tailored to the unique characteristics of each individual Active Pharmaceutical Ingredient (API). These strategies are tailored to the unique characteristics of each individual Active Pharmaceutical Ingredient (API).

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Empowering women in STEM: Navigating CMC regulatory affairs

Drug Target Review

Dr Lopa Bakrania brings over 18 years of experience in pharmaceutical process chemistry and CMC regulatory affairs. In this Q&A, Bakrania reflects on her personal journey in STEM, shares insights into her work at Biohaven, and discusses the evolving landscape of drug discovery and regulatory practices.

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