Drugs and Research - Drug Discovery Digest

Researchers make breakthrough in bioprinting functional human heart tissue

Science Daily: Pharmacology News

JANUARY 22, 2025

Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development.

Research

Research Science Disease Drugs

New research demonstrates potential for increasing effectiveness of popular diabetes, weight-loss drugs

Science Daily: Pharmacology News

JULY 15, 2024

A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of popular diabetes and weight-loss drugs, according to new research.

Research

Research Drugs

Vertex’s non-opioid pain drug gets FDA approval in milestone for company and research

BioPharma Drive: Drug Pricing

JANUARY 30, 2025

Despite high demand for an option like Journavx, doctors fear the drug’s price could be a major hangup for insurers, potentially limiting patients’ ability to access it.

FDA Approval

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Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Researchers create gel that can self-heal like human skin

Science Daily: Pharmacology News

MARCH 7, 2025

Now, a team of researchers has developed a hydrogel with a unique structure that overcomes earlier limitations, opening the door to applications such as drug delivery, wound healing, soft robotics sensors and artificial skin.

Research

Research Drugs

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. From Research to Real-World Care 🌎 Understand how AI-driven advancements are shaping personalized treatments and patient outcomes.

Clinical Trials

NIH funds research for three experimental ALS drugs

BioPharma Drive: Drug Pricing

OCTOBER 6, 2023

The funding, which is part of ACT for ALS, will support expanded access studies of drugs developed by Prilenia Therapeutics, Clene Nanomedicine and Rapa Therapeutics.

Research

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Researchers create artificial cells that act like living cells

Science Daily: Pharmacology News

APRIL 23, 2024

Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.

Research

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Early Research Points to Possible New Parkinson's Drug

Drugs.com

DECEMBER 19, 2024

Now, researchers say they are on the trail of a potential new therapy for the disabling neurological illness.It's early research. THURSDAY, Dec. 19, 2024 -- Parkinson's is a relentless disease for which few treatments, and no real cure, exists.

Research

Research Therapies Treatment Disease

Researchers discover how we perceive bitter taste

Science Daily: Pharmacology News

APRIL 10, 2024

In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

Research

Research Drugs

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management.

Clinical Trials

New research could ease concerns over suicide risk of obesity drugs

BioPharma Drive: Drug Pricing

SEPTEMBER 3, 2024

While results from two after-the-fact analyses were “reassuring,” outside experts urged “continued vigilance” to ensure GLP-1 drugs don’t worsen problems in people with preexisting mental health conditions.

Research

Research Drugs

As ALS research booms, one treatment center finds itself in the spotlight

BioPharma Drive: Drug Pricing

DECEMBER 20, 2023

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

Research

Research Doctors Treatment Drug Development

Upcoming Webinar: Interdisciplinary Pathways in Medicine- from Neurodegenerative to Oncology Disease Research and Drug Discovery

Collaborative Drug

FEBRUARY 7, 2024

Upcoming Webinar 3-21 24: Interdisciplinary Pathways in Medicine: Neurodegenerative Research and Drug Discovery

Research

Research Disease Drugs

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Science Daily: Pharmacology News

NOVEMBER 27, 2024

A tiny, four-fingered 'hand' folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, researchers report.

DNA

DNA Virus Treatment Research

AltruBio lands up to $225M after shift to immune drug research

BioPharma Drive: Drug Pricing

MAY 21, 2024

Since pivoting from oncology, the startup has raised close to $300 million and advanced an ulcerative colitis drug into mid-stage testing.

Drug Research

Drug Research Research Drugs

Diabetes Drug Protects Against Skin Cancer, New Research Says

Drugs.com

JANUARY 14, 2025

14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says.Metformin significantly reduces peoples risk of developing basal cell cancers or squamous cell cancers, the two most common skin c. TUESDAY, Jan.

Research

Research Drugs

Researchers map communities of single cells in metastatic breast cancers

Broad Institute

OCTOBER 30, 2024

Researchers map communities of single cells in metastatic breast cancers By Corie Lok October 30, 2024 Breadcrumb Home Researchers map communities of single cells in metastatic breast cancers The team compared different single-cell and spatial profiling methods to explore the diversity of cells in metastatic breast cancer biopsies.

Research

Research RNA Medical Schools Treatment

Eisai hunts for next Alzheimer’s drug with new research pact

BioPharma Drive: Drug Pricing

APRIL 22, 2024

A collaboration with BioArctic will focus on a technology designed to more effectively deliver drugs in the brain, following similar efforts by Roche.

Research

Research Drugs

Diabetes Drug, Metformin, Protects Against Skin Cancer, New Research Says

Drugs.com

JANUARY 14, 2025

14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says. TUESDAY, Jan. Metformin significantly reduces people’s risk of developing basal cell cancers or squamous cell cancers, the two most common skin.

Research

Research Drugs

Recorded Webinar: Interdisciplinary Pathways in Medicine- from Neurodegenerative to Oncology Disease Research and Drug Discovery

Collaborative Drug

MARCH 22, 2024

Recorded Webinar 3-21 24: Interdisciplinary Pathways in Medicine: Neurodegenerative Research and Drug Discovery

Research

Research Disease Drugs

Foundery, a new biotech venture firm, sets out to speed early immune drug research

BioPharma Drive: Drug Pricing

AUGUST 22, 2023

Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.

Research

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Researchers Explore New Nonaddictive Means of Fighting Pain

Drugs.com

AUGUST 3, 2023

3, 2023 -- New research shows that an experimental drug fine-tuned to a specific pain pathway can ease post-surgery aches, a finding that may eventually offer an alternative to highly addictive opioids. THURSDAY, Aug. The pill, known for now as.

Research

Research Drugs

Stomach Paralysis Risk May Rise in People Taking Ozempic and Similar Drugs

Drugs.com

MAY 20, 2024

MONDAY, May 20, 2024 -- New, real-world research confirms that the blockbuster weight-loss drugs that millions of Americans have been taking to shed pounds can trigger stomach paralysis in some patients.“Although Although these drugs do work and should be.

Drugs

Drugs Research

CDD Recognized in 2023 Gartner® Life Science Discovery Research

Collaborative Drug

AUGUST 15, 2023

Company Named as a Sample Vendor for SaaS Electronic Lab Notebook San Francisco, CA - August 15, 2023 - Collaborative Drug Discovery (CDD) is proud to announce its recent recognition as a Sample Vendor for Software-as-a-Service (SaaS) Electronic Laboratory Notebook (ELN) in the Gartner Hype Cycle for Life Science Discovery Research, 2023 report.

Science

Science Research Compliance International

Biogen, Ionis shelve ALS drug following study failure

BioPharma Drive: Drug Pricing

MAY 16, 2024

While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.

Drugs

Drugs Research

FTC, in unusual move, leads Sanofi to terminate a drug research deal

BioPharma Drive: Drug Pricing

DECEMBER 12, 2023

Just before clearing Pfizer’s buyout of Seagen, the regulator threatened to block Sanofi’s licensing deal with Maze Therapeutics, a challenge the biotech called ‘‘unprecedented.”

Drug Research

Drug Research Licensing Licensing Research

Bristol Myers’ neuroscience research head explains the big pharma’s return to brain drugs

BioPharma Drive: Drug Pricing

OCTOBER 27, 2023

In a wide-ranging interview, Bristol Myers’ Ken Rhodes talked biomarkers, diseases of interest and why the company is far from done with neuroscience-focused deals.

Research

Research Disease Drugs

Could Olumiant Be A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Drugs.com

DECEMBER 20, 2024

20, 2024 -- An existing drug might be able to treat an autoimmune disorder that causes dry eye, dry mouth, fatigue and muscle or joint pain. Baricitinib (Olumiant), a drug currently used to treat rheumatoid arthritis, appears to. FRIDAY, Dec.

Disease

Disease Research Drugs

Drug-resistant hookworms put pets and people at risk

Science Daily: Pharmacology News

JANUARY 6, 2025

Canine hookworms are becoming increasingly resistant to drugs across Australia, according to new research. Scientists have identified widespread resistance to benzimidazole-based dewormers which are commonly used to treat gastrointestinal parasites in dogs.

Drugs

Drugs Research

Stroke rehabilitation drug repairs brain damage

Science Daily: Pharmacology News

MARCH 18, 2025

A new study has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice, following from human studies.

Drugs

Drugs Research

Researchers map how the brain regulates emotions

Science Daily: Pharmacology News

APRIL 3, 2024

The findings provide new insights that could help inform therapeutic treatments regarding mental health and drug addiction. A new study is among the first of its kind to separate activity relating to emotion generation from emotion regulation in the human brain.

Regulations

Regulations Research Treatment Drugs

New paradigm of drug discovery with world's first atomic editing?

Science Daily: Pharmacology News

OCTOBER 11, 2024

Researchers have successfully develop single-atom editing technology that maximizes drug efficacy.

Drugs

Drugs Research

Synthesis and Investigation of Peptide–Drug Conjugates Comprising Camptothecin and a Human Protein‐Derived Cell‐Penetrating Peptide

Chemical Biology and Drug Design

JANUARY 20, 2025

ABSTRACT Drug targeting strategies, such as peptidedrug conjugates (PDCs), have arisen to combat the issue of off-target toxicity that is commonly associated with chemotherapeutic small molecule drugs. The PDCs crossed membranes and cleavable PDCs killed melanoma cells with nanomolar potency.

Small Molecule

Small Molecule Drugs International Therapies

Epilepsy drug prevents brain tumors in mice with NF1

Science Daily: Pharmacology News

APRIL 15, 2024

Researchers have discovered that an FDA-approved epilepsy drug can prevent or slow the growth of NF1-linked optic gliomas in mice, laying the groundwork for a clinical trial.

FDA Approval

FDA Approval Clinical Trials Drugs FDA

An innovative antibiotic for drug-resistant bacteria

Science Daily: Pharmacology News

NOVEMBER 20, 2024

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs -- so they don't work well, or even at all -- means new ones are urgently needed. Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium.

Drugs

Drugs Trials Treatment Research

Does Federally Funded Research Justify A Piece Of Pharma’s Profits?

Forbes: Drug Truths

MARCH 4, 2024

The thought that all drugs arise from government funded research is a fallacy.

Research

Research Government Drugs

NextCure to lay off 37% of staff, dial back research plans

BioPharma Drive: Drug Pricing

MARCH 21, 2024

The job cuts at the cancer drug developer will primarily impact manufacturing roles, but will touch on several other parts of the organization, the company said.

Research

Research Drug Development Drugs

CDD Recognized in 2023 Gartner® Hype Cycle™ for Life Science Discovery Research

Collaborative Drug

AUGUST 15, 2023

Company Named as a Sample Vendor for SaaS Electronic Lab Notebook San Francisco, CA - August 15, 2023 - Collaborative Drug Discovery (CDD) is proud to announce its recent recognition as a Sample Vendor for Software-as-a-Service (SaaS) Electronic Laboratory Notebook (ELN) in the Gartner Hype Cycle for Life Science Discovery Research, 2023 report.

Science

Science Research Compliance International

Human beliefs about drugs could have dose-dependent effects on the brain

Science Daily: Pharmacology News

JANUARY 3, 2024

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

Drugs

Drugs Research

Genesis raises $200 million for AI drug discovery research

BioPharma Drive: Drug Pricing

AUGUST 21, 2023

The Series B round brings the total funding for Genesis, a California startup backed by Andreessen Horowitz and Nvidia’s VC arm, to over $280 million.

Research

Research Drugs

A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Drugs.com

DECEMBER 20, 2024

20, 2024 -- An existing drug might be able to treat an autoimmune disorder that causes dry eye, dry mouth, fatigue and muscle or joint pain.Baricitinib (Olumiant), a drug currently used to treat rheumatoid arthritis, appears to. FRIDAY, Dec.

Disease

Disease Research Drugs

Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria

Science Daily: Pharmacology News

FEBRUARY 21, 2024

About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.

Research

Research Drugs

No Suicide Risk Associated With GLP-1 Drugs

Drugs.com

FEBRUARY 28, 2025

28, 2025 -- GLP-1 drugs like Ozempic/Wegovy dont increase a persons risk of suicidal actions or thoughts, a new study has concluded.Earlier research had potentially linked these drugs -- which are used to treat type 2 diabetes and obe. FRIDAY, Feb.

Drugs

Drugs Research

Could Drugs Used to Fight Cancer Also Slow Alzheimer's?

Drugs.com

AUGUST 23, 2024

23, 2024 -- A new type of cancer drug might help treat brain diseases like Alzheimer’s, mouse studies suggest.The drugs block an enzyme called indoleamine-2,3-dioxygenase 1 (IDO1), researchers reported.IDO1 inhibitors are being d. FRIDAY, Aug.

Drugs

Drugs Disease Research

Researchers make breakthrough in bioprinting functional human heart tissue

New research demonstrates potential for increasing effectiveness of popular diabetes, weight-loss drugs

Webinars

Trending Sources

Vertex’s non-opioid pain drug gets FDA approval in milestone for company and research

Webinars

Researchers create gel that can self-heal like human skin

Bridging Innovation & Patient Care: The Growing Role of AI

NIH funds research for three experimental ALS drugs

Researchers create artificial cells that act like living cells

Early Research Points to Possible New Parkinson's Drug

Researchers discover how we perceive bitter taste

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

New research could ease concerns over suicide risk of obesity drugs

As ALS research booms, one treatment center finds itself in the spotlight

Upcoming Webinar: Interdisciplinary Pathways in Medicine- from Neurodegenerative to Oncology Disease Research and Drug Discovery

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

AltruBio lands up to $225M after shift to immune drug research

Diabetes Drug Protects Against Skin Cancer, New Research Says

Researchers map communities of single cells in metastatic breast cancers

Eisai hunts for next Alzheimer’s drug with new research pact

Diabetes Drug, Metformin, Protects Against Skin Cancer, New Research Says

Recorded Webinar: Interdisciplinary Pathways in Medicine- from Neurodegenerative to Oncology Disease Research and Drug Discovery

Foundery, a new biotech venture firm, sets out to speed early immune drug research

Researchers Explore New Nonaddictive Means of Fighting Pain

Stomach Paralysis Risk May Rise in People Taking Ozempic and Similar Drugs

CDD Recognized in 2023 Gartner® Life Science Discovery Research

Biogen, Ionis shelve ALS drug following study failure

FTC, in unusual move, leads Sanofi to terminate a drug research deal

Bristol Myers’ neuroscience research head explains the big pharma’s return to brain drugs

Could Olumiant Be A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Drug-resistant hookworms put pets and people at risk

Stroke rehabilitation drug repairs brain damage

Researchers map how the brain regulates emotions

New paradigm of drug discovery with world's first atomic editing?

Synthesis and Investigation of Peptide–Drug Conjugates Comprising Camptothecin and a Human Protein‐Derived Cell‐Penetrating Peptide

Epilepsy drug prevents brain tumors in mice with NF1

An innovative antibiotic for drug-resistant bacteria

Does Federally Funded Research Justify A Piece Of Pharma’s Profits?

NextCure to lay off 37% of staff, dial back research plans

CDD Recognized in 2023 Gartner® Hype Cycle™ for Life Science Discovery Research

Human beliefs about drugs could have dose-dependent effects on the brain

Genesis raises $200 million for AI drug discovery research

A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful

Researchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria

No Suicide Risk Associated With GLP-1 Drugs

Could Drugs Used to Fight Cancer Also Slow Alzheimer's?

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