Drugs and Treatment - Drug Discovery Digest

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Science Daily: Pharmacology News

NOVEMBER 27, 2024

Dubbed the NanoGripper, the nanorobotic hand also could be programmed to interact with other viruses or to recognize cell surface markers for targeted drug delivery, such as for cancer treatment.

DNA

DNA Virus Treatment Research

Americans Got Drug-Resistant Infections After Stem Cell Treatments in Mexico

Drugs.com

MAY 9, 2024

medical tourists" brought home after seeking out unapproved stem cell treatments in Mexico, according to a new report.The. THURSDAY, May 9, 2024 -- Antibiotic-resistant meningitis or severe, long-lasting joint infections: That's what three U.S.

Treatment

Treatment Drugs

Discovery of 'new rules of the immune system' could improve treatment of inflammatory diseases, say scientists

Science Daily: Pharmacology News

JUNE 18, 2024

Tests, in mice, of a drug developed by the researchers showed that regulatory T cells can be attracted to specific body parts, boosted in number, and activated to suppress immune response and rebuild tissue. Clinical trials in humans are now planned.

Treatment

Treatment Immune Response Disease Clinical Trials

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Bridging Innovation & Patient Care: The Growing Role of AI

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Narcolepsy Drug, Solriamfetol, Might Be New Treatment Option for ADHD

Drugs.com

OCTOBER 11, 2023

11, 2023 -- A medication already approved for excessive daytime sleepiness may help ease attention-deficit/hyperactivity disorder (ADHD) symptoms in adults who aren’t getting relief from available treatments, according to a. WEDNESDAY, Oct.

Treatment

Treatment Drugs

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. From Research to Real-World Care 🌎 Understand how AI-driven advancements are shaping personalized treatments and patient outcomes. But its impact goes far beyond research.

Clinical Trials

FDA Approves Symbravo for Acute Treatment of Migraine in Adults

Drugs.com

FEBRUARY 5, 2025

Food and Drug Administration has approved Symbravo (meloxicam and rizatriptan) for the acute treatment of migraine with or without aura in adults. WEDNESDAY, Feb. 5, 2025 -- The U.S. The approval was based on the results of three phase 3 trials of.

FDA Approval

FDA Approval Treatment FDA Trials

FDA Panel Says No to MDMA as Treatment for PTSD

Drugs.com

JUNE 5, 2024

Food and Drug Administration advisory panel on Tuesday voted against recommending the psychedelic MDMA for the treatment of post-traumatic stress disorder (PTSD).In WEDNESDAY, June 5, 2024 -- A U.S. In a 10-1 vote, the panel determined the evidence.

Treatment

Treatment FDA Drugs

Women with a common hormonal disorder have few good treatment options. Could GLP-1 drugs help?

BioPharma Drive: Drug Pricing

JUNE 26, 2024

Obesity drugs like Wegovy are proving useful in many other diseases. Polycystic ovary syndrome, a chronic condition that can cause infertility, may be one.

Treatment

Treatment Drugs Disease

About 6% of U.S. Adults Have ADHD, Drug Shortages Are Affecting Treatment

Drugs.com

OCTOBER 10, 2024

adults have been diagnosed with ADHD, and nearly three-quarters of those taking medication to treat it say drug shortages are hampering their ability to get help, a new report finds. THURSDAY, Oct. 10, 2024 -- More than 15.5 million U.S. According.

Treatment

Treatment Drugs

New drug shows promise in clearing HIV from brain

Science Daily: Pharmacology News

JULY 25, 2024

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.

Virus

Virus Drugs Treatment

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

Science Daily: Pharmacology News

FEBRUARY 17, 2025

The findings demonstrate the potential of this technology to pave the way for future treatments for a wide range of conditions such as Alzheimer's disease, amyotrophic lateral sclerosis, brain cancer, and drug addiction.

RNA

RNA Treatment Disease Drugs

FDA Asked to Consider Party Drug MDMA as Treatment for PTSD

Drugs.com

DECEMBER 13, 2023

Food and Drug Administration to approve MDMA, the active ingredient in party drugs like molly and ecstasy, as a treatment for post-traumatic stress disorder (PTSD).When WEDNESDAY, Dec. 13, 2023 -- A California company has asked the U.S. When announcing.

Treatment

Treatment FDA Drugs

Just 1 in 20 Animal Studies Yield Treatments That Make it to Humans

Drugs.com

JUNE 14, 2024

FRIDAY, June 14, 2024 -- Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies. Only 5% of therapies tested.

Treatment

Treatment Therapies Disease Drugs

New Type of Treatment Tackles Tough-to-Treat Prostate Cancer

Drugs.com

JULY 13, 2023

THURSDAY, July 13, 2023 -- A preclinical study offers a potential new therapy for treatment-resistant prostate cancer, offering new hope for men with the disease. The study used the chemotherapy drug cisplatin, administered orally, to disrupt the.

Treatment

Treatment Therapies Disease Drugs

Any Kind of Drug Abuse Treatment Can Help Gay Men Kick Meth Habit

Drugs.com

DECEMBER 5, 2023

5, 2023 -- Methamphetamine abuse has long plagued the gay community, but a new study finds that any form of substance abuse treatment can help users quit. TUESDAY, Dec. In a news release, University of California, Los Angeles researchers explained.

Treatment

Treatment Drugs Research

As ALS research booms, one treatment center finds itself in the spotlight

BioPharma Drive: Drug Pricing

DECEMBER 20, 2023

Still, the complexities of the disease and of drug development have brought hard-felt losses. The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists.

Research

Research Doctors Treatment Drug Development

Golgi Neurosciences Partners with CDD Vault to Drive Innovation in Neurodegenerative Disease Treatment

Collaborative Drug

AUGUST 29, 2023

a new Italian incubator dedicated to the discovery and development of small molecule-based treatments for neurodegenerative diseases, announced today that it has adopted Collaborative Drug Discovery’s CDD Vault as its platform of choice for managing drug discovery data.

Small Molecule

Small Molecule Treatment Disease Research

FDA Expands Use of Breast Cancer Drug Kisqali

Drugs.com

SEPTEMBER 18, 2024

Food and Drug Administration's expanded approval of the treatment, drug maker Novartis. WEDNESDAY, Sept. 18, 2024 -- Women with early stage breast cancer may now take Kisquali, a medication already approved for advanced disease, following the U.S.

FDA

FDA Drugs Treatment Disease

GSK builds case for return of multiple myeloma drug Blenrep

BioPharma Drive: Drug Pricing

JUNE 2, 2024

Study results showed the antibody-drug conjugate helped stave off disease progression better than a standard treatment. But eye-related side effects remained common.

Drugs

Drugs Treatment Disease

FDA Approves Spravato Nasal Spray for Treatment-Resistant Depression

Drugs.com

JANUARY 22, 2025

Food and Drug Administration has approved Spravato (esketamine) CIII nasal spray for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants. WEDNESDAY, Jan. 22, 2025 -- The U.S.

FDA Approval

FDA Approval Treatment FDA Drugs

Reviewing the IDH1 Mutation‐Mediated Mechanism of Drug Resistance and Revisiting Its Overcoming Strategies

Chemical Biology and Drug Design

APRIL 4, 2025

At present, there are few studies on the drug resistance of mIDH1 inhibitors. It is found that a significant cause for drug resistance is that IDH1 has mutation at the second site. Isocitrate dehydrogenase (IDH) is a key metabolic enzyme that catalyzes the conversion of isocitrate to -ketoglutaric acid (-KG).

Small Molecule

Small Molecule DNA Drugs Treatment

Versant startup sets out to make a new type of obesity drug

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2024

The startup, Pep2Tango, is combining four methods of accelerating weight loss into one medicine in the hopes of developing a treatment that can improve upon drugs like Wegovy and Zepbound.

Drugs

Drugs Treatment

Children surpass a year of HIV remission after treatment pause

Science Daily: Pharmacology News

MARCH 7, 2024

The children, who acquired HIV before birth, were enrolled in a clinical trial in which an ART regimen was started within 48 hours of birth and then closely monitored for drug safety and HIV viral suppression.

Treatment

Treatment Clinical Trials Therapies Trials

New postpartum depression drugs are here. Diagnosis, treatment hurdles still stand in the way.

BioPharma Drive: Drug Pricing

APRIL 10, 2024

The first medicine approved for PPD, Sage’s Zulresso, never gained traction. The company is in the midst of launching its second, but long-standing challenges could slow uptake.

Treatment

Treatment Drugs

Anti-amyloid drug shows signs of preventing Alzheimer's dementia

Science Daily: Pharmacology News

MARCH 19, 2025

An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study.

Clinical Trials

Clinical Trials Drugs Trials Treatment

Ipsen drug for rare liver disease approved by FDA

BioPharma Drive: Drug Pricing

JUNE 11, 2024

The medicine will join Intercept’s Ocaliva as a treatment option for primary biliary cholangitis. Another drug, from the now Gilead-owned CymaBay, could be cleared for the condition by August.

Disease

Disease FDA Drugs Treatment

New MS Drug Kesimpta May Help Keep Symptoms at Bay

Drugs.com

JULY 18, 2024

THURSDAY, July 18, 2024 -- A new monoclonal antibody treatment called Kesimpta (ofatumumab) appears to improve on an older drug in pushing multiple sclerosis (MS) into remission, a new trial shows.Funded by Kesimpta's maker, Novartis, the trial.

Drugs

Drugs Trials Treatment

ALS drug effectively treats Alzheimer's disease in new animal study

Science Daily: Pharmacology News

APRIL 8, 2025

Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves neuron health in animal models of Alzheimer's disease, according to a new study.

Small Molecule

Small Molecule Disease Clinical Trials Drugs

An innovative antibiotic for drug-resistant bacteria

Science Daily: Pharmacology News

NOVEMBER 20, 2024

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs -- so they don't work well, or even at all -- means new ones are urgently needed. Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium.

Drugs

Drugs Trials Treatment Research

Commonly Used Drug Amitriptyline Might Be New Treatment Option for IBS

Drugs.com

OCTOBER 18, 2023

WEDNESDAY, Oct. 18, 2023 -- An inexpensive medication long used for depression and migraines now has a clinical trial to back up its off-label use for another condition that lowers quality of life: irritable bowel syndrome (IBS). In the study,

Clinical Trials

Clinical Trials Treatment Trials Drugs

After surprise trial failure, ALS doctors brace for one less treatment option

BioPharma Drive: Drug Pricing

MARCH 12, 2024

Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.

Doctors

Doctors Treatment Trials Pharmaceuticals

Sarepta scraps a Duchenne drug as gene therapy sales rise

BioPharma Drive: Drug Pricing

NOVEMBER 7, 2024

Now, Sarepta is abandoning a successor to its drug Exondys 51, citing an “evolving" treatment landscape. Elevidys sales have increased since the FDA made a controversial choice to expand the therapy's use.

Therapies

Therapies Drugs FDA Treatment

Daiichi Sankyo, with new data, to seek FDA approval of lung cancer drug

BioPharma Drive: Drug Pricing

SEPTEMBER 11, 2023

The HER3-targeting treatment could become the next antibody-drug conjugate to emerge from Daiichi Sankyo’s laboratories, after the AstraZeneca-partnered Enhertu.

FDA Approval

FDA Approval Laboratories FDA Drugs

Lilly gene therapy finding puts focus on hearing loss treatment pipeline

BioPharma Drive: Drug Pricing

JANUARY 24, 2024

are taking aim at the same drug target. An 11-year-old boy born deaf can hear after receiving Lilly's genetic medicine. Others, including biotechs in China and Regeneron in the U.S.,

Therapies

Therapies Treatment Drugs

Injectable Drug, Xolair, Resolves Dangerous Food Allergies In One-Third Of Kids

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report. In all, 36% of children treated with.

Clinical Trials

Clinical Trials Drugs Trials Treatment

AI enabled soft robotic implant monitors scar tissue to self-adapt for personalized drug treatment

Science Daily: Pharmacology News

AUGUST 30, 2023

Research teams have detailed a pioneering breakthrough in medical device technology that could lead to intelligent, long-lasting, tailored treatment for patients, thanks to soft robotics and artificial intelligence.

Treatment

Treatment Research Drugs

In Small Study, Ozempic Helped People With Type 1 Diabetes Quit Insulin Treatments

Drugs.com

SEPTEMBER 7, 2023

7, 2023 -- The blockbuster drug Ozempic has become a household name for its ability to spur weight loss. Now an early study hints at an intriguing possibility: The drug might allow people newly diagnosed with type 1 diabetes to drop. THURSDAY, Sept.

Treatment

Treatment Drugs

Combo Drug, Kadcyla, Boosts Survival in Some Women With Early Breast Cancer

Drugs.com

JUNE 28, 2024

FRIDAY, June 28, 20204 (HealthDay news) -- An immunotherapy/chemotherapy combo drug can help early-stage breast cancer patients remain cancer-free following treatment, a new trial shows. The combo drug, Kadcyla, is already approved to treat.

Drugs

Drugs Trials Treatment

Hospital Drug Tests Far More Likely for Minority Teens

Drugs.com

OCTOBER 4, 2024

4, 2024 -- Teens from minority groups seeking treatment at pediatric trauma centers are more likely than their white counterparts to be tested for drugs and alcohol.That's the takeaway from a new study led by researchers at UCLA and. FRIDAY, Oct.

Hospitals

Hospitals Drugs Treatment Research

Upping Dose of Anti-Opioid Drug Might Work Better to Curb Addiction

Drugs.com

SEPTEMBER 27, 2024

FRIDAY, September 27, 2024 -- Patients with opioid use disorder who receive higher doses of a drug to treat their addiction are more likely to have positive results, a new study finds. Daily doses of the drug buprenorphine is a standard treatment.

Drugs

Drugs Treatment

FDA to Import Syphilis Drug, Extencilline, From France Amid Shortage

Drugs.com

JANUARY 11, 2024

11, 2024 -- Amid an ongoing shortage of the first-line treatment for syphilis in the United States, the U.S. Food and Drug Administration will allow the importation of a different syphilis drug from a French drugmaker. THURSDAY, Jan.

FDA

FDA Drugs Treatment

Novel drug delivery platform paves way to potential new treatments for Alzheimer's, other brain-related disorders

Science Daily: Pharmacology News

APRIL 9, 2025

Researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

Treatment

Treatment Therapies Disease Research

Study shows anti-clotting drug reduced bleeding events in patients with atrial fibrillation

Science Daily: Pharmacology News

JANUARY 22, 2025

Researchers evaluated a drug that represents a new class of anticoagulants known as Factor XI inhibitors for treating patients with atrial fibrillation as part of the AZALEA-TIMI 71 Study.

Drugs

Drugs Trials Treatment Research

Regulator and Funder? FDA’s Orphan Products Grants Program awards significant funding to help move promising treatments through clinical development

FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. The Natural History Studies Grants Program funds natural history studies that collect gather data on how rare diseases progress over time without treatment.

Clinical Development

Clinical Development Production Clinical Trials Treatment

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Americans Got Drug-Resistant Infections After Stem Cell Treatments in Mexico

Webinars

Trending Sources

Discovery of 'new rules of the immune system' could improve treatment of inflammatory diseases, say scientists

Webinars

Narcolepsy Drug, Solriamfetol, Might Be New Treatment Option for ADHD

Bridging Innovation & Patient Care: The Growing Role of AI

FDA Approves Symbravo for Acute Treatment of Migraine in Adults

FDA Panel Says No to MDMA as Treatment for PTSD

Women with a common hormonal disorder have few good treatment options. Could GLP-1 drugs help?

About 6% of U.S. Adults Have ADHD, Drug Shortages Are Affecting Treatment

New drug shows promise in clearing HIV from brain

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

FDA Asked to Consider Party Drug MDMA as Treatment for PTSD

Just 1 in 20 Animal Studies Yield Treatments That Make it to Humans

New Type of Treatment Tackles Tough-to-Treat Prostate Cancer

Any Kind of Drug Abuse Treatment Can Help Gay Men Kick Meth Habit

As ALS research booms, one treatment center finds itself in the spotlight

Golgi Neurosciences Partners with CDD Vault to Drive Innovation in Neurodegenerative Disease Treatment

FDA Expands Use of Breast Cancer Drug Kisqali

GSK builds case for return of multiple myeloma drug Blenrep

FDA Approves Spravato Nasal Spray for Treatment-Resistant Depression

Reviewing the IDH1 Mutation‐Mediated Mechanism of Drug Resistance and Revisiting Its Overcoming Strategies

Versant startup sets out to make a new type of obesity drug

Children surpass a year of HIV remission after treatment pause

New postpartum depression drugs are here. Diagnosis, treatment hurdles still stand in the way.

Anti-amyloid drug shows signs of preventing Alzheimer's dementia

Ipsen drug for rare liver disease approved by FDA

New MS Drug Kesimpta May Help Keep Symptoms at Bay

ALS drug effectively treats Alzheimer's disease in new animal study

An innovative antibiotic for drug-resistant bacteria

Commonly Used Drug Amitriptyline Might Be New Treatment Option for IBS

After surprise trial failure, ALS doctors brace for one less treatment option

Sarepta scraps a Duchenne drug as gene therapy sales rise

Daiichi Sankyo, with new data, to seek FDA approval of lung cancer drug

Lilly gene therapy finding puts focus on hearing loss treatment pipeline

Injectable Drug, Xolair, Resolves Dangerous Food Allergies In One-Third Of Kids

AI enabled soft robotic implant monitors scar tissue to self-adapt for personalized drug treatment

In Small Study, Ozempic Helped People With Type 1 Diabetes Quit Insulin Treatments

Combo Drug, Kadcyla, Boosts Survival in Some Women With Early Breast Cancer

Hospital Drug Tests Far More Likely for Minority Teens

Upping Dose of Anti-Opioid Drug Might Work Better to Curb Addiction

FDA to Import Syphilis Drug, Extencilline, From France Amid Shortage

Novel drug delivery platform paves way to potential new treatments for Alzheimer's, other brain-related disorders

Study shows anti-clotting drug reduced bleeding events in patients with atrial fibrillation

Regulator and Funder? FDA’s Orphan Products Grants Program awards significant funding to help move promising treatments through clinical development

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