Drugs.com

DECEMBER 4, 2024

4, 2024 -- Zepbound, the new GLP-1 weight-loss drug from Eli Lilly & Co., has outperformed its main competitor, Wegovy, in a clinical trial funded by Lilly."Given WEDNESDAY, Dec. Given the increased interest around obesity medications, we conducted.

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Trials Clinical Trials Drugs 111

Antidote

NOVEMBER 9, 2023

Before any new treatment or therapy is able to be used by the patient population, it must go through the process of a clinical trial — this is the case for any new prescription drug, but also true for over-the-counter medications, medical devices, and more.

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Clinical Trials Trials Therapies Treatment 126

Drugs.com

NOVEMBER 3, 2023

3, 2023 -- The first new antibiotic for gonorrhea — the second most common sexually transmitted disease — has shown promise in a clinical trial. FRIDAY, Nov. That news should come as a relief to public health experts, because gonorrhea.

Trials 126

Trials Clinical Trials Disease Drugs 126

BioPharma Drive: Drug Pricing

JANUARY 30, 2024

The company plans to soon ask the FDA for approval of the drug, which it has pitched as a safer alternative to addictive opioid painkillers.

Trials 136

Trials FDA Drugs 136

Quanticate

SEPTEMBER 13, 2024

With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively.

Clinical Trials 95

Clinical Trials Trials Drug Development Treatment 95

BioPharma Drive: Drug Pricing

MARCH 29, 2024

Confirmatory results for Krazati, which Bristol Myers acquired via its buyout of Mirati, could help the drug win full approval while Amgen has been set back.

Trials 122

Trials Drugs 122

BioPharma Drive: Drug Pricing

AUGUST 1, 2024

The drug led to a 38% reduction in the risk of death or complications from a type of heart failure, a finding that compared favorably to available treatments.

Trials 124

Trials Drugs Treatment 124

BioPharma Drive: Drug Pricing

APRIL 8, 2024

Underrepresentation of women in clinical trials affects the resulting drugs that become available later. Even small changes could boost participation.

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Clinical Trials Trials Drugs 119

BioPharma Drive: Drug Pricing

AUGUST 29, 2024

The trial setbacks for Merck’s best-selling drug, which faces patent expiration in 2028, are a blow to the company’s plans for further indication expansion.

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Trials Drugs 111

BioPharma Drive: Drug Pricing

FEBRUARY 26, 2024

Zealand shares rose by more than one-third on the data, which provide further evidence so-called incretin drugs could help treat people with the liver disease.

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Trials Drugs Disease 119

Drugs.com

OCTOBER 1, 2024

1, 2024 -- Clinical trials sponsored by Big Pharma enrolled eight times as many patients as U.S.-government government trials did between 2018 and 2022, new research shows.The study -- conducted by researchers at Fred Hutch Cancer Center in. TUESDAY, Oct.

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Trials Clinical Trials Government Drugs 96

Drugs.com

DECEMBER 15, 2023

15, 2023 -- A new melanoma vaccine has shown its mettle in battling the deadly skin cancer in a new trial. People with advanced melanomas who received the vaccine plus Merck's cancer drug Keytruda were 49% less likely to die or have. FRIDAY, Dec.

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Vaccine Trials Treatment Drugs 116

Drug Hunter

JULY 21, 2023

With the popular success of diabetes and weight-loss peptide drugs from Novo (e.g. danuglipron – An oral GLP-1-RA full agonist in Phase IIb clinical trials for obesity and Phase II trials for type 2 diabetes mellitus, identified through sensitized cell high-throughput screening and optimization, originated from Pfizer.

Structure Based Drug Design (SBDD) 227

Structure Based Drug Design (SBDD) Targeted Protein Degradation Clinical Trials Trials 227

BioPharma Drive: Drug Pricing

JUNE 20, 2024

Interim study data suggest the Danish drugmaker can remain in the race to develop new kinds of weight loss drugs as doctors seek alternatives to the now dominant GLP-1s.

Trials 115

Trials Doctors Drugs 115

Forbes: Drug Truths

AUGUST 8, 2023

The SELECT trial is a game changer. But obesity patients with heart disease now have a major new drug to extend their lives – and that’s an even bigger win. Yes, Novo Nordisk achieved winning results.

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Drugs Trials Disease 171

BioPharma Drive: Drug Pricing

MARCH 5, 2024

The study results further validate Roche’s recent decision to acquire rights to the drug, which is being developed for people with a stubborn form of hypertension.

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Trials Drugs 122

Drugs.com

JUNE 24, 2024

MONDAY, June 24, 2024 -- Just two injections a year of a new HIV drug protected young women in Africa from infection with the sexually transmitted disease, new trial results show.In announcing the findings, Gilead Sciences Inc. said its HIV.

Trials 111

Trials Science Disease Drugs 111

BioPharma Drive: Drug Pricing

APRIL 10, 2024

The company said the pause is necessary to meet regulatory limits on nitrosamine, but added it will not affect commercial supply nor regulatory review of the drug in early breast cancer.

Trials 119

Trials Drugs 119

BioPharma Drive: Drug Pricing

DECEMBER 4, 2024

Results from the head-to-head study showed treatment with Zepbound resulted in 47% greater relative weight loss than Wegovy, a finding that could advantage Lilly in the companies’ market competition.

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Drug Trials Trials Treatment Marketing 126

Drug Hunter

AUGUST 15, 2023

LRRK2 has been a hotly pursued drug target for Parkinson’s Disease based on human genetics. Initial Detection of A Distinct Toxicity Related to LRRK2 Inhibition request a trial You don’t have time to read everything, but you can’t afford to fall behind. Get ahead now by requesting a trial. already a member?

Small Molecule 229

Small Molecule Trials Treatment Disease 229

PPD

JUNE 24, 2024

In the realm of vaccine development, mega trials — studies enrolling 5,000 subjects or more — have been instrumental in the fight against many pathogens, including influenza, rotavirus, malaria, RSV and most recently in the rapid development of vaccines against COVID-19.

Vaccine 97

Vaccine Trials Clinical Trials Laboratories 97

BioPharma Drive: Drug Pricing

NOVEMBER 27, 2023

drugmaker withdrew the multiple myeloma drug from the U.S. One year after the U.K. market because of negative data, new study results might crack open the door to a relaunch.

Trials 115

Trials Drugs Marketing 115

Drug Target Review

JULY 4, 2023

Over the last two decades, an increasing number of Antibody Drug Conjugate (ADC) therapeutics have been approved for oncology indications. These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. 3D rendering of Antibody Drug Conjugate Molecules.

Small Molecule 145

Small Molecule Drugs Clinical Pharmacology Trials 145

Conversations in Drug Development Trends

MAY 10, 2024

Over the past two decades, industry-sponsored clinical trials have targeted treatments for BPD, yielding some promising outcomes; however, broader psychiatric research often excludes BPD patients, a trend that extends to the emerging field of psychedelic studies.

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Clinical Trials Trials Treatment Drug Development 95

ASPET

DECEMBER 22, 2023

Canine cell lines and primary cells are sensitive to PTL and undergo dose-dependent apoptosis following exposure to drug. These data support further investigation of compounds that can antagonize canonical NF-kB pathway signaling in these cancers and pave the way for clinical trials of PTL in affected dogs.

Clinical Trials 189

Clinical Trials Disease Drugs Therapies 189

BioPharma Drive: Drug Pricing

FEBRUARY 15, 2024

Analysts pressed Alnylam executives on the reasons for the changes to HELIOS-B, a Phase 3 study in ATTR amyloidosis with cardiomyopathy that is important to the company’s future.

Drug Trials 130

Drug Trials Trials Drugs 130

BioPharma Drive: Drug Pricing

JUNE 26, 2024

The failure of a Phase 3 trial led the Wegovy maker to take an accounting charge that will hit its operating profit growth this year.

Trials 96

Trials Drugs 96

BioPharma Drive: Drug Pricing

MAY 16, 2024

Full study results disclosed ahead of a medical meeting showed elinzanetant consistently reduced the frequency and severity of hot flashes.

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Trials Drugs 122

Drug Hunter

MAY 31, 2023

Capacity Bio’s MAS Receptor Agonists with $35M Raised for FIH Clinical Trials MAS modulator from WO2022165189 example 107 New start-up Capacity Bio backed by RA Capital, Insight Partners, and Remiges Ventures with $35 million funding is working on taking first-in-class mitophagy agonists into clinical trials, which are expected to start in 2024.

Small Molecule 196

Small Molecule Clinical Trials Trials Drugs 196

Drug Hunter

SEPTEMBER 17, 2023

III clinical trials such as Vertex’s sodium channel inhibitor for acute pain and Denali Therapeutics’ CNS-penetrant eIF2B activator for ALS. selective inhibitor developed by Vertex Pharmaceuticals for acute pain in Phase III clinical trials. The post Molecules of the Month – August 2023 appeared first on Drug Hunter.

Clinical Trials 206

Clinical Trials Trials Therapies Pharmaceuticals 206

PPD

AUGUST 5, 2024

Historically, the available drugs and U.S. Food and Drug Administration (FDA)-approved therapies for treating PAH were primarily vasodilators, designed to overcome the imbalance between vasoactive and vasodilator mediators and to restore endothelial cell function.

Clinical Trials 98

Clinical Trials Trials Clinical Research Disease 98

Science Daily: Pharmacology News

APRIL 15, 2024

Researchers have discovered that an FDA-approved epilepsy drug can prevent or slow the growth of NF1-linked optic gliomas in mice, laying the groundwork for a clinical trial.

FDA Approval 133

FDA Approval Clinical Trials FDA Drugs 133

BioPharma Drive: Drug Pricing

FEBRUARY 27, 2024

The biotech’s drug led to significant weight loss in a Phase 2 trial, causing shares to double as analysts compared results to the marks set by drugs from Eli Lilly and Novo Nordisk.

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Drugs Trials 126

Drug Hunter

OCTOBER 5, 2023

With initial signs of efficacy and tolerability, Drug Hunter is launching into Phase III! At Drug Hunter, we love structures so much that we forgot to include basic things like headlines and abstracts. appeared first on Drug Hunter. In a few days, you’ll see the changeover to the new version go live. drughunter.com.

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Trials Drugs 247

BioPharma Drive: Drug Pricing

JULY 1, 2024

Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.

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Clinical Trials Trials Drugs 136

Drug Hunter

MAY 22, 2023

request a trial You don’t have time to read everything, but you can’t afford to fall behind. Drug Hunter Premium is drug discovery, distilled, so you can quickly catch up and make informed decisions based on industry examples. Get ahead now by requesting a trial. already a member?

Drugs 133

Drugs Trials Disease 133

Drug Patent Watch

OCTOBER 8, 2024

A recent study published in Drug Discovery Today highlights the potential of artificial intelligence (AI) in revolutionizing drug discovery and development processes[1].

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Clinical Trials Drugs Pharmaceuticals Trials 123